2022-03-01
|
R-HSA-9689680
|
IFNG dimer binds IFNG inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9691621
|
C5 binds C5 inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9724670
|
C-ter TLR7 dimer binds imiquimod
|
BibTex
|
2022-03-01
|
R-HSA-9692376
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BCL2 binds BCL2 antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9648949
|
HTR3A antagonists bind HTR3A pentamer
|
BibTex
|
2022-03-01
|
R-HSA-9691421
|
BTK binds BTK inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9725706
|
SLC12A3 binds SLC12A3 inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9734535
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SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA
|
BibTex
|
2022-03-01
|
R-HSA-9717841
|
holo-FDPS dimer binds NBPs
|
BibTex
|
2022-03-01
|
R-HSA-9705584
|
HMGCR dimer binds statins
|
BibTex
|
2022-03-01
|
R-HSA-9757010
|
SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol
|
BibTex
|
2022-03-01
|
R-HSA-9660192
|
VDR agonists bind VDR
|
BibTex
|
2022-03-01
|
R-HSA-9695917
|
SPHK2 binds SPHK2 inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9731931
|
EDNRA binds selective ERAs
|
BibTex
|
2022-03-01
|
R-HSA-9731393
|
EDNRA, EDNRB bind non-selective ERAs
|
BibTex
|
2022-03-01
|
R-HSA-9667619
|
AVPR1A,B,2 bind atosiban
|
BibTex
|
2022-03-01
|
R-HSA-9667569
|
AVPR1A,2 bind AVPR antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9667456
|
AVPR1A,B bind desmopressin
|
BibTex
|
2022-03-01
|
R-HSA-9667563
|
AVPR2 bind desmopressin
|
BibTex
|
2022-03-01
|
R-HSA-9696323
|
CNRs bind CNR agonists
|
BibTex
|
2022-03-01
|
R-HSA-9718360
|
GNRHR binds GNRHR peptide agonists
|
BibTex
|
2022-03-01
|
R-HSA-9718394
|
GNRHR binds GNRHR peptide antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9718379
|
GNRHR binds chemical antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9704151
|
CHRM1,3,5 bind CHRM1,3,5 antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9704248
|
CHRM4 binds CHRM4 antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9704297
|
CHRM2 binds CHRM2 antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9626914
|
?2-agonists bind ADRA2A,B,C
|
BibTex
|
2022-03-01
|
R-HSA-9611751
|
?1,2-agonists bind ADRB1,2
|
BibTex
|
2022-03-01
|
R-HSA-9617370
|
?1-antagonists bind ADRA1A,B,D
|
BibTex
|
2022-03-01
|
R-HSA-9623384
|
?1-agonists bind ADRA1A,B,D
|
BibTex
|
2022-03-01
|
R-HSA-9611721
|
?1-agonists bind ADRB1
|
BibTex
|
2022-03-01
|
R-HSA-9654054
|
DRD2 antagonist drugs bind to DRD2
|
BibTex
|
2022-03-01
|
R-HSA-9692867
|
HRH3 binds pitosilant
|
BibTex
|
2022-03-01
|
R-HSA-9692738
|
HRH2 binds HRH2 antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9692539
|
HRH1 binds HRH1 inverse agonists
|
BibTex
|
2022-03-01
|
R-HSA-9693478
|
HTR1A binds HTR1A agonists
|
BibTex
|
2022-03-01
|
R-HSA-9648268
|
HTR1A binds HTR1A antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9718020
|
PTGFR binds PTGFR agonists
|
BibTex
|
2022-03-01
|
R-HSA-9708275
|
PDE4A binds PDE4A inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9629679
|
PDE3A inhibitors bind PDE3A
|
BibTex
|
2022-03-01
|
R-HSA-9708759
|
DHODH:FMN binds DHODH inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9696179
|
IFNAR2:JAK1:STAT2 binds type 1 interferon analogs
|
BibTex
|
2022-03-01
|
R-HSA-9707827
|
Spike binds Spike inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9707419
|
CA1:Zn2+,CA2:Zn2+ bind CA inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9728150
|
SLC5A2 binds gliflozins
|
BibTex
|
2022-03-01
|
R-HSA-9733403
|
PCSK9 binds PCSK9 inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9659611
|
ANO1 inhibitors bind ANO1
|
BibTex
|
2022-03-01
|
R-HSA-9701064
|
TRPV1 binds TRPV1 agonists
|
BibTex
|
2022-03-01
|
R-HSA-9701211
|
TRPA1 tetramer binds TRPA1 antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9701147
|
TRPV1 binds TRPV1 blockers
|
BibTex
|
2022-03-01
|
R-HSA-9649963
|
ASIC3 channel blockers bind ASIC3 trimer
|
BibTex
|
2022-03-01
|
R-HSA-9727188
|
ATP4A:ATP4B binds PPIs
|
BibTex
|
2022-03-01
|
R-HSA-9726580
|
PGR binds PGR agonists
|
BibTex
|
2022-03-01
|
R-HSA-9706837
|
AR binds AR antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9726621
|
PGR binds PGR antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9725855
|
NR3C2 binds NR3C2 antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9705926
|
AR binds AR agonists
|
BibTex
|
2022-03-01
|
R-HSA-9726509
|
NR3C2 binds fludrocortisone
|
BibTex
|
2022-03-01
|
R-HSA-9732629
|
PPARG binds PPARG agonists
|
BibTex
|
2022-03-01
|
R-HSA-9709109
|
DHFR dimer binds DHFR inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9705794
|
SRD5A2 binds SRD5A2 inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9707353
|
CYP19A1 binds Aromatase inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9677929
|
MAOB inhibitors bind MAOB:FAD
|
BibTex
|
2022-03-01
|
R-HSA-9677917
|
MAOA inhibitors bind MAOA:FAD
|
BibTex
|
2022-03-01
|
R-HSA-9680865
|
CYP3A4, CYP2B6 bind ritonavir
|
BibTex
|
2022-03-01
|
R-HSA-9678766
|
CYP3A4 binds CYP3A4 inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9700266
|
CFTR F508del binds CFTR correctors
|
BibTex
|
2022-03-01
|
R-HSA-9732527
|
FFAR1 binds rosiglitazone
|
BibTex
|
2022-03-01
|
R-HSA-9652580
|
SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer)
|
BibTex
|
2022-03-01
|
R-HSA-9728664
|
GLP1R binds GLP1R agonists
|
BibTex
|
2022-03-01
|
R-HSA-9650858
|
Meglitinides bind ABCC8
|
BibTex
|
2022-03-01
|
R-HSA-9714415
|
SLC6A4 binds TCAs and SSRIs
|
BibTex
|
2022-03-01
|
R-HSA-9714580
|
SLC6A3 binds DRIs
|
BibTex
|
2022-03-01
|
R-HSA-9677320
|
PTGS1 dimer binds PTGS1 Inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9756180
|
CYP3A4 monooxygenates ATVL to 4-OH-ATVL
|
BibTex
|
2022-03-01
|
R-HSA-9756156
|
UGT1A3 lactonizes ATV to ATVL
|
BibTex
|
2022-03-01
|
R-HSA-9756134
|
UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL
|
BibTex
|
2022-03-01
|
R-HSA-9756169
|
CYP3A4 monooxygenates ATV to 2-OH-ATV
|
BibTex
|
2022-03-01
|
R-HSA-9756150
|
PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV
|
BibTex
|
2022-03-01
|
R-HSA-9756183
|
UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL
|
BibTex
|
2022-03-01
|
R-HSA-9756162
|
CYP3A4 monooxygenates ATV to 4-OH-ATV
|
BibTex
|
2022-03-01
|
R-HSA-9756177
|
PON1,3 hydrolyse ATVL to ATV
|
BibTex
|
2022-03-01
|
R-HSA-9757139
|
ABCB1,ABCC2 transport ATVs from cytosol to extracellular region
|
BibTex
|
2022-03-01
|
R-HSA-9756136
|
PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV
|
BibTex
|
2022-03-01
|
R-HSA-9756138
|
CYP3A4 monooxygenates ATVL to 2-OH-ATVL
|
BibTex
|
2022-03-01
|
R-HSA-9708866
|
pro-F2R binds vorapaxar
|
BibTex
|
2022-03-01
|
R-HSA-9724753
|
PLG(20-810) binds anti-fibrinolytics
|
BibTex
|
2022-03-01
|
R-HSA-9724745
|
PLG(20-810) binds aprotinin
|
BibTex
|
2022-03-01
|
R-HSA-9726949
|
PTGIR binds PTGIR agonists
|
BibTex
|
2022-03-01
|
R-HSA-9734475
|
PPARA binds fibrates
|
BibTex
|
2022-03-01
|
R-HSA-9707186
|
ALOX5 binds ALOX5 inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9709179
|
DPP4 binds DPP4 inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9621179
|
Cinaciguat binds sGC:NO
|
BibTex
|
2022-03-01
|
R-HSA-9700701
|
T-type VDCC bind T-type VDCC blockers
|
BibTex
|
2022-03-01
|
R-HSA-9620103
|
ALDH2 transforms GTN to NO
|
BibTex
|
2022-03-01
|
R-HSA-9620456
|
sGC stimulators bind sGC:NO
|
BibTex
|
2022-03-01
|
R-HSA-9708104
|
PDE5A dimer binds PDE5A inhibitors
|
BibTex
|
2022-03-01
|
R-HSA-9691566
|
KCNJ11:ABCC9 binds nicorandil
|
BibTex
|
2022-03-01
|
R-HSA-9613570
|
Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers
|
BibTex
|
2022-03-01
|
R-HSA-9613264
|
Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE
|
BibTex
|
2022-03-01
|
R-HSA-9614031
|
Class IV antihypertensives bind LTCC multimer
|
BibTex
|
2022-03-01
|
R-HSA-9727607
|
MME:Zn2+ binds sacubitrilat
|
BibTex
|
2022-03-01
|
R-HSA-9727567
|
CES1 hydrolyses sacubitril to sacubitrilat
|
BibTex
|
2022-03-01
|
R-HSA-9726875
|
HCNs:cAMP bind SNIs
|
BibTex
|
2022-03-01
|
R-HSA-9703895
|
CASR binds CASR agonists
|
BibTex
|
2022-03-01
|
R-HSA-9702849
|
CALCR binds gepants
|
BibTex
|
2022-03-01
|
R-HSA-9702354
|
CALCA(83-119) binds CALCA antibodies
|
BibTex
|
2022-03-01
|
R-HSA-9702818
|
CALCR binds erenumab
|
BibTex
|
2022-03-01
|
R-HSA-9733292
|
AMY1-3 bind pramlintide
|
BibTex
|
2022-03-01
|
R-HSA-9709454
|
EPOR binds EPOR agonists
|
BibTex
|
2022-03-01
|
R-HSA-9716913
|
ESR1 binds ESR1 antagonists
|
BibTex
|
2022-03-01
|
R-HSA-9716947
|
ESR1 binds ESR1 agonists
|
BibTex
|
2022-03-01
|
R-HSA-9009817
|
Acitretin binds to RAR:RXR
|
BibTex
|
2021-10-19
|
R-HSA-9748949
|
GUK1 phosphorylates 6TGMP to 6TGDP
|
BibTex
|
2021-10-19
|
R-HSA-9748957
|
GMPS dimer transforms 6TXMP to 6TGMP
|
BibTex
|
2021-10-19
|
R-HSA-9748945
|
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP
|
BibTex
|
2021-10-19
|
R-HSA-9748951
|
HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP
|
BibTex
|
2021-10-19
|
R-HSA-9748996
|
GST dimers cleave AZA to 6MP
|
BibTex
|
2021-10-19
|
R-HSA-9748983
|
TPMT transfers methyl group to 6MP, forming 6MeMP
|
BibTex
|
2021-10-19
|
R-HSA-9751024
|
SLC29A1,2 transport 6MP from extracellular region to cytosol
|
BibTex
|
2021-10-19
|
R-HSA-9751051
|
GSH cleaves AZA to 6MP
|
BibTex
|
2021-10-19
|
R-HSA-9751037
|
SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol
|
BibTex
|
2021-10-19
|
R-HSA-9750546
|
ABCC4 transports TPMP substrates from cytosol to extracellular region
|
BibTex
|
2021-10-19
|
R-HSA-9748979
|
TPMT transfers methyl group to 6TIMP, forming 6MeTIMP
|
BibTex
|
2021-10-19
|
R-HSA-9748991
|
XDH oxidises 6MP to 6TU
|
BibTex
|
2021-10-19
|
R-HSA-9750617
|
ABCC5 transports TPMP substrates from cytosol to extracellular region
|
BibTex
|
2021-10-19
|
R-HSA-9750555
|
NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP
|
BibTex
|
2021-10-19
|
R-HSA-9748969
|
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP
|
BibTex
|
2021-10-19
|
R-HSA-9748963
|
GUK1 phosphorylates 6TdGMP to 6TdGDP
|
BibTex
|
2021-10-19
|
R-HSA-9748999
|
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP
|
BibTex
|
2021-10-19
|
R-HSA-9751201
|
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1
|
BibTex
|
2021-10-13
|
R-HSA-9749607
|
SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells
|
BibTex
|
2021-10-13
|
R-HSA-9757434
|
Acetylsalicylic acid dissolves
|
BibTex
|
2021-10-13
|
R-HSA-9749583
|
SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes
|
BibTex
|
2021-10-13
|
R-HSA-9757441
|
ASA- (GI) translocates from cytosol to extracellular region
|
BibTex
|
2021-10-13
|
R-HSA-9757445
|
ST translocates from ER lumen to cytosol of GI cells
|
BibTex
|
2021-10-13
|
R-HSA-9749647
|
CES2 hydrolyzes ASA-
|
BibTex
|
2021-10-13
|
R-HSA-9757438
|
ASA- translocates from cytosol to ER lumen of GI cells
|
BibTex
|
2021-10-13
|
R-HSA-9757448
|
ST translocates from cytosol to extracellular region
|
BibTex
|
2021-10-13
|
R-HSA-9749609
|
BCHE hydrolyzes ASA-
|
BibTex
|
2021-10-13
|
R-HSA-9757454
|
ST translocates from cytosol to mitochondrial matrix of hepatocytes
|
BibTex
|
2021-10-13
|
R-HSA-9757451
|
ASA-,ST translocate from cytosol to ER lumen of hepatocytes
|
BibTex
|
2021-10-13
|
R-HSA-9753944
|
ACY1:Zn2+ dimer deacetylates NAC to L-Cys
|
BibTex
|
2021-10-13
|
R-HSA-9749792
|
CES1,CES2 hydrolyze ASA- to ST
|
BibTex
|
2021-10-13
|
R-HSA-9753916
|
NAPQI binds proteins in hepatocytes
|
BibTex
|
2021-10-13
|
R-HSA-9753285
|
CYP2E1 monooxygenates APAP to NAPQI
|
BibTex
|
2021-10-13
|
R-HSA-9754180
|
APAP translocates from extracellular region to cytosol
|
BibTex
|
2021-10-13
|
R-HSA-9753277
|
SULT dimers sulfate APAP to APAP-SO3
|
BibTex
|
2021-10-13
|
R-HSA-9753278
|
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3
|
BibTex
|
2021-10-13
|
R-HSA-158546
|
UGTs glucuronate APAP to APAP-GlcA
|
BibTex
|
2021-10-13
|
R-HSA-9753284
|
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region
|
BibTex
|
2021-10-13
|
R-HSA-9753632
|
CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly
|
BibTex
|
2021-10-13
|
R-HSA-9753634
|
GGT dimers hydrolyse APAP-SG
|
BibTex
|
2021-10-13
|
R-HSA-9753280
|
GSTs transfer GSH to NAPQI to form APAP-SG
|
BibTex
|
2021-10-13
|
R-HSA-9753676
|
NAT1,2 acetylate APAP-Cys to APAP-Mer
|
BibTex
|
2021-10-13
|
R-HSA-9753283
|
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3
|
BibTex
|
2021-10-13
|
R-HSA-9749590
|
ASA- acetylates ALB
|
BibTex
|
2021-10-13
|
R-HSA-9757462
|
Hydroxyl radicals oxidize ST to 2,3-DHBA
|
BibTex
|
2021-10-13
|
R-HSA-9757456
|
2,5-DHBA translocates from ER lumen to mitochondrial matrix
|
BibTex
|
2021-10-13
|
R-HSA-9750016
|
CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA
|
BibTex
|
2021-10-13
|
R-HSA-9749971
|
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA
|
BibTex
|
2021-10-13
|
R-HSA-9750001
|
GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid
|
BibTex
|
2021-10-13
|
R-HSA-9757459
|
ST metabolites diffuse out of ER lumen
|
BibTex
|
2021-10-13
|
R-HSA-9749986
|
CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA
|
BibTex
|
2021-10-13
|
R-HSA-9749977
|
UGT1A6 glucuronates ST
|
BibTex
|
2021-10-13
|
R-HSA-9750660
|
Glycine conjugates translocates from mitochondrial matrix to cytosol
|
BibTex
|
2021-10-13
|
R-HSA-9750656
|
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells
|
BibTex
|
2021-10-13
|
R-HSA-9750666
|
ALB binds ST
|
BibTex
|