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James A Borowiec

 ORCID
Affiliation
NYU School of Medicine, Department of Biochemistry
Reviewed Reactions (294)
Date Identifier Reaction Reference
2015-06-12 R-HSA-5683735 CHEK2 is recruited to DNA DSBs BibTex
2015-06-12 R-HSA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM BibTex
2015-06-12 R-HSA-5683385 Formation of BRCA1-A complex at DNA DSBs BibTex
2015-06-12 R-HSA-5659781 BRCA1 forms a heterodimer with BARD1 BibTex
2015-06-12 R-HSA-5683384 UIMC1 and FAM175A bind DNA DSBs BibTex
2015-06-12 R-HSA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs BibTex
2015-06-12 R-HSA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs BibTex
2015-06-12 R-HSA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B BibTex
2015-06-12 R-HSA-5682858 RNF8 and RNF168 ubiquitinate H2AFX BibTex
2015-06-12 R-HSA-5682863 RNF168 binds DNA DSBs BibTex
2015-06-12 R-HSA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 BibTex
2015-06-12 R-HSA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs BibTex
2015-06-12 R-HSA-5682598 ATM phosphorylates HERC2 BibTex
2015-06-12 R-HSA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs BibTex
2015-06-12 R-HSA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs BibTex
2015-06-12 R-HSA-5682992 KDM4A,B bind H4K20Me2 BibTex
2015-06-12 R-HSA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs BibTex
2015-06-12 R-HSA-5682983 ATM phosphorylates WHSC1 BibTex
2015-06-12 R-HSA-5682967 WHSC1 binds DNA DSBs BibTex
2015-06-12 R-HSA-5693536 ATM phosphorylates MDC1 BibTex
2015-06-12 R-HSA-5693583 MDC1 associates with gamma-H2AFX at nuclear foci BibTex
2015-06-12 R-HSA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX BibTex
2015-06-12 R-HSA-5683964 ATM phosphorylates EYA1-4 BibTex
2015-06-12 R-HSA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs BibTex
2015-06-12 R-HSA-5693602 ATM recognizes H2AFX-Nucleosomes BibTex
2015-06-12 R-HSA-5683930 WICH phosphorylates H2AFX on Y142 BibTex
2015-06-12 R-HSA-5693598 ATM phosphorylates NBN BibTex
2013-09-03 R-HSA-5693540 MRN activates ATM BibTex
2015-06-12 R-HSA-5682044 KAT5 acetylates ATM at DNA DSBs BibTex
2013-09-03 R-HSA-5693612 MRN complex bound to DNA ends recruits ATM BibTex
2013-09-03 R-HSA-3785768 MRN complex binds DNA double strand breaks BibTex
2015-06-12 R-HSA-75174 Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction BibTex
2015-06-12 R-HSA-5684006 KPNA2 translocates NBN to the nucleus BibTex
2015-06-12 R-HSA-5684008 NBN binds KPNA2 BibTex
2015-06-12 R-HSA-75172 Formation of RAD50:MRE11 complex BibTex
2013-09-03 R-HSA-3785704 DSB inducing agents induce double strand DNA breaks BibTex
2015-06-12 R-HSA-69891 Phosphorylation and activation of CHEK2 by ATM BibTex
2008-05-07 R-HSA-5693609 ATM phosphorylates TP53 at S15 BibTex
2015-06-12 R-HSA-5685011 ATR activation at DNA DSBs BibTex
2015-06-12 R-HSA-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs BibTex
2015-06-12 R-HSA-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs BibTex
2015-06-12 R-HSA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 BibTex
2015-06-12 R-HSA-5693561 RAD51 binds BRCA2 at resected DNA DSBs BibTex
2015-06-12 R-HSA-5685230 CHEK1 phosphorylates RAD51 BibTex
2015-06-12 R-HSA-5684887 Activation of CHEK1 at resected DNA DSBs BibTex
2015-06-12 R-HSA-5684882 CHEK1 is recruited to resected DNA DSBs BibTex
2015-06-12 R-HSA-5685156 ATR phosphorylates RPA2 BibTex
2015-06-12 R-HSA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 BibTex
2015-06-12 R-HSA-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment BibTex
2015-06-12 R-HSA-5693608 Initial resection of double-strand break ends BibTex
2015-06-12 R-HSA-5684108 BRCA1 binds phosphorylated RBBP8 BibTex
2015-06-12 R-HSA-5684140 ATM phosphorylates RBBP8 BibTex
2015-06-12 R-HSA-5684096 CDK2 phosphorylates RBBP8 BibTex
2015-06-12 R-HSA-5684081 MRN complex binds CDK2 and RBBP8 BibTex
2015-06-12 R-HSA-5685953 SIRT6 deacetylates RBBP8 BibTex
2015-06-12 R-HSA-5684071 RNF4 ubiquitinates MDC1 BibTex
2015-06-12 R-HSA-5684052 PIAS4 SUMOylates MDC1 BibTex
2015-06-12 R-HSA-5683801 CHEK2 phosphorylates BRCA1 BibTex
2015-06-12 R-HSA-5683792 p-T68-CHEK2 autophosphorylates BibTex
2015-06-12 R-HSA-5683774 p-T68-CHEK2 dimerizes BibTex
2015-06-12 R-HSA-5685242 CHEK1 phosphorylates BRCA2 BibTex
2015-06-12 R-HSA-5686578 Activated ATM phosphorylates ABL1 BibTex
2015-06-12 R-HSA-5683405 PPP5C dephosphorylates TP53BP1 BibTex
2015-06-12 R-HSA-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX BibTex
2015-06-12 R-HSA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ BibTex
2015-06-12 R-HSA-5687465 MRN complex binds RBBP8 BibTex
2015-06-12 R-HSA-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site BibTex
2015-06-12 R-HSA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate BibTex
2015-06-12 R-HSA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ BibTex
2015-06-12 R-HSA-5687675 LIG3 ligates remaining SSBs in MMEJ BibTex
2015-06-12 R-HSA-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites BibTex
2015-06-12 R-HSA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ BibTex
2015-06-12 R-HSA-5686900 TP53BP1 recruits DCLRE1C to ATM BibTex
2015-06-12 R-HSA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs BibTex
2015-06-12 R-HSA-5686704 Activated ATM phosphorylates DCLRE1C BibTex
2015-06-12 R-HSA-5693599 Association of Ku heterodimer with ends of DNA double-strand break BibTex
2015-06-12 R-HSA-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends BibTex
2015-06-12 R-HSA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs BibTex
2015-06-12 R-HSA-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs BibTex
2015-06-12 R-HSA-5693575 DNA-PKcs autophosphorylates BibTex
2015-06-12 R-HSA-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis BibTex
2015-06-12 R-HSA-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ BibTex
2015-06-12 R-HSA-5693578 TDP1 and TDP2 process unligatable DSB ends BibTex
2015-06-12 R-HSA-5693604 XRCC4:LIG4 ligates DNA DSB ends during NHEJ BibTex
2015-06-12 R-HSA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps BibTex
2015-06-12 R-HSA-5693558 Gap-filling DNA synthesis in SDSA BibTex
2015-06-12 R-HSA-5693589 D-loop dissociation and strand annealing BibTex
2015-06-12 R-HSA-5693593 D-loop extension by DNA polymerases BibTex
2015-06-12 R-HSA-5685838 CX3 complex binds D-loop structures BibTex
2015-06-12 R-HSA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 BibTex
2015-06-12 R-HSA-5685341 BCDX2 complex stabilizes RAD51 filament BibTex
2015-06-12 R-HSA-5685318 BCDX2 complex formation BibTex
2015-06-12 R-HSA-5685319 CX3 complex formation BibTex
2015-06-12 R-HSA-5686469 Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 BibTex
2015-06-12 R-HSA-5686440 MUS81:EME1,EME2 cleaves D-loop BibTex
2015-06-12 R-HSA-5686430 MUS81 binds EME1, EME2 BibTex
2015-06-12 R-HSA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis BibTex
2015-06-12 R-HSA-5686483 Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) BibTex
2015-06-12 R-HSA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) BibTex
2015-06-12 R-HSA-5686475 SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) BibTex
2015-06-12 R-HSA-5686398 SPIDR binds BLM:TOP3A:RMI1:RMI2 BibTex
2015-06-12 R-HSA-5686410 BLM mediates dissolution of double Holliday junction BibTex
2015-06-12 R-HSA-5686663 Completion of SSA BibTex
2015-06-12 R-HSA-5686657 ERCC1:XPF cleaves flaps generated by SSA BibTex
2015-06-12 R-HSA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs BibTex
2015-06-12 R-HSA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends BibTex
2015-06-12 R-HSA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs BibTex
2015-06-12 R-HSA-5686587 ABL1 phosphorylates RAD52 BibTex
2015-06-12 R-HSA-75998 Formation of RAD52 heptameric ring structure complexes BibTex
2015-01-07 R-HSA-5655892 POLK incorporates dNMP opposite to damaged DNA base BibTex
2015-01-07 R-HSA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template BibTex
2015-01-07 R-HSA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA BibTex
2015-01-07 R-HSA-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA BibTex
2015-01-07 R-HSA-5651992 PCNA-containing replication complex binds damaged dsDNA BibTex
2015-01-07 R-HSA-5652137 Damaged dsDNA becomes damaged DNA template BibTex
2015-01-07 R-HSA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini BibTex
2015-01-07 R-HSA-5655142 RCHY1 binds POLH BibTex
2015-01-07 R-HSA-5655170 RCHY1 monoubiquitinates POLH BibTex
2015-01-07 R-HSA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA BibTex
2015-01-07 R-HSA-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH BibTex
2015-01-07 R-HSA-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH BibTex
2015-01-07 R-HSA-110319 Elongation by POLH BibTex
2015-01-07 R-HSA-110317 Insertion of correct bases opposite the lesion by POLH BibTex
2015-01-07 R-HSA-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template BibTex
2015-01-07 R-HSA-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template BibTex
2015-01-07 R-HSA-110308 REV1 inserts dCMP opposite to AP sites in DNA BibTex
2015-01-07 R-HSA-110307 REV1 binds AP-dsDNA BibTex
2015-01-07 R-HSA-110311 POLZ extends translesion synthesis BibTex
2015-01-07 R-HSA-5656148 POLI incorporates dNMP opposite to damaged DNA base BibTex
2015-01-07 R-HSA-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA BibTex
2015-01-07 R-HSA-5656158 POLZ elongates POLI-incorporated dNMP BibTex
2015-01-07 R-HSA-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA BibTex
2015-01-07 R-HSA-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA BibTex
2015-01-07 R-HSA-5653756 TRIM25 binds monoUb:164-PCNA BibTex
2015-01-07 R-HSA-5653780 USP43 binds ISG:K164,ISG:K168-PCNA BibTex
2015-01-07 R-HSA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA BibTex
2015-01-07 R-HSA-5653840 POLD,POLE complete replication of damaged DNA after TLS BibTex
2015-01-07 R-HSA-5653838 POLD,POLE binds deISGylated PCNA after TLS BibTex
2015-01-07 R-HSA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA BibTex
2015-01-07 R-HSA-5655193 KIAA0101 double monoubiquitination BibTex
2015-01-07 R-HSA-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA BibTex
2015-01-07 R-HSA-5655481 USP1:WDR48 binds monoUb:K164-PCNA BibTex
2015-01-07 R-HSA-5655483 USP1 autocleavage BibTex
2014-12-22 R-HSA-110243 Cleavage of 8-oxoguanine by OGG1 glycosylase BibTex
2014-12-22 R-HSA-110235 OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine BibTex
2014-12-22 R-HSA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH BibTex
2014-12-22 R-HSA-110237 MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine BibTex
2014-12-22 R-HSA-110248 Cleavage of 3-methyladenine by MPG glycosylase BibTex
2014-12-22 R-HSA-110238 MPG glycosylase mediated recognition and binding of 3-methyladenine BibTex
2014-12-22 R-HSA-110251 Cleavage of hypoxanthine by MPG glycosylase BibTex
2014-12-22 R-HSA-110240 MPG glycosylase mediated recognition and binding of hypoxanthine BibTex
2014-12-22 R-HSA-110250 Cleavage of ethenoadenine by MPG glycosylase BibTex
2014-12-22 R-HSA-110239 MPG glycosylase mediated recognition and binding of ethenoadenine BibTex
2014-12-22 R-HSA-110244 Cleavage of formamidopyrimidine (FapyG) by OGG1 glycosylase BibTex
2014-12-22 R-HSA-110236 OGG1 glycosylase mediated recognition and binding of a formamidopyrimidine (FapyG) BibTex
2014-12-22 R-HSA-110215 Cleavage of uracil by UNG glycosylase BibTex
2014-12-22 R-HSA-110156 UNG glycosylase mediated recognition and binding of an uracil opposite to a guanine BibTex
2014-12-22 R-HSA-5649681 NEIL2 cleaves 5-OHU from damaged DNA BibTex
2014-12-22 R-HSA-5649686 NEIL2 recognizes and binds 5-OHU-dsDNA BibTex
2014-12-22 R-HSA-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase BibTex
2014-12-22 R-HSA-110157 UNG glycosylase mediated recognition and binding of a 5-hydroxyuracil opposite to a guanine BibTex
2014-12-22 R-HSA-110219 Cleavage of thymine by TDG glycosylase BibTex
2014-12-22 R-HSA-110158 TDG glycosylase mediated recognition and binding of a thymine opposite to a guanine BibTex
2014-12-22 R-HSA-110218 Cleavage of uracil by TDG glycosylase BibTex
2014-12-22 R-HSA-110159 TDG glycosylase mediated recognition and binding of an uracil opposite to a guanine BibTex
2014-12-22 R-HSA-110221 Cleavage of uracil by SMUG1 glycosylase BibTex
2014-12-22 R-HSA-110164 SMUG1 glycosylase mediated recognition and binding of uracil in DNA BibTex
2014-12-22 R-HSA-5649658 NEIL1 cleaves DHU from damaged DNA BibTex
2014-12-22 R-HSA-5649655 NEIL1 recognizes and binds DHU-dsDNA BibTex
2014-12-22 R-HSA-110224 Cleavage of thymine glycol by NTHL1 glycosylase BibTex
2014-12-22 R-HSA-110211 NTHL1 glycosylase mediated recognition and binding of thymine glycol BibTex
2014-12-22 R-HSA-110227 Cleavage of dihydrouracil by NTHL1 glycosylase BibTex
2014-12-22 R-HSA-110212 NTHL1 glycosylase mediated recognition and binding of dihydrouracil BibTex
2014-12-22 R-HSA-110226 Cleavage of cytosine glycol by NTHL1 glycosylase BibTex
2014-12-22 R-HSA-110208 NTHL1 glycosylase mediated recognition and binding of cytosine glycol BibTex
2014-12-22 R-HSA-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase BibTex
2014-12-22 R-HSA-110213 NTHL1 glycosylase mediated recognition and binding of formamidopyrimidine (FapyA) BibTex
2014-12-22 R-HSA-110231 Cleavage of uracil by MBD4 glycosylase BibTex
2014-12-22 R-HSA-110171 MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences BibTex
2014-12-22 R-HSA-5649664 NEIL1 cleaves FapyG from damaged DNA BibTex
2014-12-22 R-HSA-5649657 NEIL1 recognizes and binds FapyG-dsDNA BibTex
2014-12-22 R-HSA-110232 Cleavage of thymine by MBD4 glycosylase BibTex
2014-12-22 R-HSA-110172 MBD4 glycosylase mediated recognition and binding of a thymine opposite to a guanine at CpG sequences BibTex
2014-12-22 R-HSA-110234 Cleavage of ethenocytosine by TDG glycosylase BibTex
2014-12-22 R-HSA-110210 TDG glycosylase mediated recognition and binding of an ethenocytosine BibTex
2014-12-22 R-HSA-5649673 NEIL1 cleaves FapyA from damaged DNA BibTex
2014-12-22 R-HSA-5649671 NEIL1 recognizes and binds FapyA-dsDNA BibTex
2014-12-22 R-HSA-5649734 LIG3 ligates NEIL1,NEIL2-generated single strand break BibTex
2014-12-22 R-HSA-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution BibTex
2014-12-22 R-HSA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) BibTex
2014-12-22 R-HSA-5649726 LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA BibTex
2014-12-22 R-HSA-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) BibTex
2014-12-22 R-HSA-5649708 NEIL1,NEIL2 recruits POLB to incised AP site BibTex
2014-12-22 R-HSA-5649711 NEIL1,NEIL2 incises DNA strand 5' to the AP site BibTex
2014-12-22 R-HSA-5649701 NEIL1,NEIL2 displace OGG1 from AP-dsDNA BibTex
2014-12-22 R-HSA-5649724 LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site BibTex
2014-12-22 R-HSA-110353 Displacement of MBD4 glycosylase by APEX1 at the AP site BibTex
2014-12-22 R-HSA-110352 Displacement of NTHL1 glycosylase by APEX1 at the AP site BibTex
2014-12-22 R-HSA-110355 Displacement of MUTYH glycosylase by APEX1 at the AP site BibTex
2014-12-22 R-HSA-110354 Displacement of OGG1 glycosylase by APEX1 at the AP site BibTex
2014-12-22 R-HSA-110356 Displacement of MPG glycosylase by APEX1 at the AP site BibTex
2014-12-22 R-HSA-110349 Displacement of UNG glycosylase by APEX1 at the AP site BibTex
2014-12-22 R-HSA-110351 Displacement of SMUG1 glycosylase by APEX1 at the AP site BibTex
2014-12-22 R-HSA-110350 Displacement of TDG glycosylase by APEX1 at the AP site BibTex
2014-12-22 R-HSA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site BibTex
2014-12-22 R-HSA-5649854 Recruitment of POLB to oxidatively damaged AP site BibTex
2014-12-22 R-HSA-5649856 Oxidative damage to the AP site BibTex
2014-12-22 R-HSA-110359 APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site BibTex
2014-12-22 R-HSA-5651782 FEN1 bound to POLB cleaves displaced DNA strand (flap) BibTex
2014-12-22 R-HSA-5651739 PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB BibTex
2014-12-22 R-HSA-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate BibTex
2014-12-22 R-HSA-5649883 POLB-mediated DNA strand displacement synthesis BibTex
2014-12-22 R-HSA-5649873 PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site BibTex
2014-12-22 R-HSA-5651828 PARG dePARylates PARP1,PARP2 BibTex
2014-12-22 R-HSA-5651792 LIG1 and POLB dissociate from repaired dsDNA BibTex
2014-12-22 R-HSA-5651789 LIG1 bound to POLB ligates SSB BibTex
2014-12-22 R-HSA-5651773 LIG1 binds POLB at long-patch BER site BibTex
2014-12-22 R-HSA-110368 POLD,POLE-mediated DNA strand displacement synthesis BibTex
2014-12-22 R-HSA-110364 PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 BibTex
2014-12-22 R-HSA-110371 LIG1 binds APEX1 and PCNA at SSB BibTex
2014-12-22 R-HSA-110363 FEN1 bound to PCNA and APEX1 cleaves flap ssDNA BibTex
2014-12-22 R-HSA-5651809 LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA BibTex
2014-12-22 R-HSA-5651805 LIG1 bound to APEX1 and PCNA ligates SSB BibTex
2014-12-22 R-HSA-110376 Recruitment of LIG3:XRCC1 complex to the site of repair by POLB BibTex
2014-12-22 R-HSA-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break BibTex
2014-12-22 R-HSA-110360 Recruitment of POLB to the AP site BibTex
2014-12-22 R-HSA-73931 LIG3-mediated DNA ligation via the single-nucleotide replacement pathway BibTex
2014-12-22 R-HSA-73932 Resynthesis of excised residue by POLB BibTex
2014-12-22 R-HSA-110380 Dissociation of LIG3:XRCC1 complex from the BER site BibTex
2009-04-23 R-GGA-351412 Association of MRE11 and NBS1 leads to nuclear localization of MRN complex BibTex
2009-04-23 R-GGA-351407 Association of MRE11 with RAD50 BibTex
2009-04-23 R-GGA-217209 Generation of a DNA double strand break BibTex
2009-04-23 R-GGA-217136 Phosphorylation of Chk1 by ATM upon DNA damage BibTex
2009-04-23 R-GGA-217204 Activation and association of ATM kinase at the DNA damage sites BibTex
2009-04-23 R-GGA-216941 Phosphorylation of Chk1 by ATR BibTex
2009-04-23 R-GGA-265858 Activation of ATR by interaction with RAD9-TopBP1 complex BibTex
2009-04-23 R-GGA-265823 Association between RAD9 and TopBP1 BibTex
2009-04-23 R-GGA-353300 MGMT mediated DNA Damage Reversal BibTex
2009-04-23 R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases BibTex
2009-04-23 R-GGA-353476 Recruitment of repair factors to form the preincision complex BibTex
2009-04-23 R-GGA-353526 Repair of ~27-30 bp long patch by DNA Pol Epsilon BibTex
2009-04-23 R-GGA-353524 XP-C binds to RAD23B forming a heterodimer BibTex
2009-04-23 R-GGA-353314 XP-C-RAD23B heterodimer binds to damaged DNA site with lesion BibTex
2009-04-23 R-GGA-353500 Nuclear focus formation by interaction of chSNM1A with PIAS1 upon DNA lesion BibTex
2009-04-23 R-GGA-353323 Ligation of newly synthesized repair patch to incised DNA in GG-NER BibTex
2009-04-23 R-GGA-353243 Monoubiquitunated PCNA mediates recruitment of the translesion polymerase to the DNA damaged site. BibTex
2009-04-23 R-GGA-216988 Monoubiquitination of PCNA BibTex
2009-04-23 R-GGA-353430 Binding of Pol eta to a DNA template containing a lesion BibTex
2009-04-23 R-GGA-353504 Insertion of correct bases opposite to the lesion by Pol eta BibTex
2009-04-23 R-GGA-353435 Elongation by Pol eta BibTex
2009-04-23 R-GGA-353268 Binding of Pol zeta complex to a DNA template containing lesions BibTex
2009-04-23 R-GGA-353434 Formation of Pol zeta complex BibTex
2009-04-23 R-GGA-353273 Elongation by Pol zeta complex BibTex
2009-04-23 R-GGA-353301 Binding of Pol kappa and REV1 complex to the lesion on the template DNA strand BibTex
2009-04-23 R-GGA-353460 REV1-Pol kappa complex formation BibTex
2009-04-23 R-GGA-353318 Insertion of correct bases opposite to the lesion by Pol kappa BibTex
2009-04-23 R-GGA-353494 Elongation by Pol kappa BibTex
2009-04-23 R-GGA-353444 Cleavage of thymine by TDG glycosylase BibTex
2009-04-23 R-GGA-353426 TDG glycosylase mediated recognition and binding of thymine opposite guanine BibTex
2009-04-23 R-GGA-353271 Cleavage of uracil by Uracil-glycosylase BibTex
2009-04-23 R-GGA-353484 Uracil glycosylase mediated recognition and binding of uracil opposite guanine BibTex
2009-04-23 R-GGA-353277 Cleavage of thymine by 5-methylcytosine G/T mismatch specific glycosylase BibTex
2009-04-23 R-GGA-353481 5-methylcytosine G/T mismatch specific DNA glycosylase mediated recognition and binding of thymine opposite guanine at CpG sequences BibTex
2009-04-23 R-GGA-353472 Displacement of DNA glycosylase and endonucleolytic cleavage by DNA-lyase BibTex
2009-04-23 R-GGA-353516 Ligation of DNA at sites of patch replacement BibTex
2009-04-23 R-GGA-265973 Monoubiquitination of FANCI BibTex
2009-04-23 R-GGA-265894 BRIP1 (FANCJ) helicase functions in direct unwinding of DNA BibTex
2009-04-23 R-GGA-217150 Monoubiquitination of FancD2 BibTex
2009-04-23 R-GGA-217017 Deubiquitination of FancD2 BibTex
2009-04-23 R-GGA-265951 Phosphorylation of FANCG at S7 BibTex
2009-04-23 R-GGA-351429 Association of 53BP1 with gamma H2AX at double strand break BibTex
2009-04-23 R-GGA-351434 Phosphorylation of H2AX at S139 by ATM at the site of DSB BibTex
2009-04-23 R-GGA-351478 Association of gamma-H2AX with MCPH1 BibTex
2009-04-23 R-GGA-351456 Association of gamma H2AX and NBS1 BibTex
2009-04-23 R-GGA-265940 Rad51 assembly at the DNA-damage sites on the chromatin BibTex
2009-04-23 R-GGA-217013 Phosphorylation of RAD51 by tyrosine kinase Abelson family protein members BibTex
2009-04-23 R-GGA-217147 Phosphorylation of c-Abl and Arg by ATM BibTex
2009-04-23 R-GGA-265959 Phosphorylation of Chk2 by ATM upon DNA damage BibTex
2009-04-23 R-GGA-265987 Phosphorylation of BRCA1 BibTex
2009-04-23 R-GGA-351455 Phosphorylation of NBS1 by ATM BibTex
2009-04-23 R-GGA-217152 Formation of a multi-protein complex, cohesin BibTex
2009-04-23 R-GGA-265887 Binding of RPA heterotrimer to 3' double stranded DNA break BibTex
2009-04-23 R-GGA-265867 Formation of RPA-heterotrimer BibTex
2009-04-23 R-GGA-265862 Association of RAD51 with BRCA2 BibTex
2009-04-23 R-GGA-265968 Association of RAD51 with BRCA1 BibTex
2009-04-23 R-GGA-265936 Phosphorylation of RPA2 by CDC2 kinase BibTex
2009-04-23 R-GGA-217097 Formation of the Rad17-RFC alternate clamp-loader complex BibTex
2009-04-23 R-GGA-353265 Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB BibTex
2009-04-23 R-GGA-353283 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks BibTex
2009-04-23 R-GGA-353455 Autophosphorylation of DNA-PKcs BibTex
2009-04-23 R-GGA-353226 Association of Ku heterodimer with ends of DNA double-strand breaks BibTex
2009-04-23 R-GGA-353313 Removal of 3'-phosphoglycolate (PG) moiety from DSB ends BibTex
2009-04-23 R-GGA-353475 Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex BibTex
2009-04-23 R-GGA-353298 Removal of repair proteins and ligation of the processed ends of the DNA double-strand break BibTex