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Roel Nusse

 ORCID
Reviewed Reactions (35)
Date Identifier Reaction Reference
2008-01-19 R-MMU-209096 Murine Axin1 is dephosphorylated by PP2A leading to reduced binding affinity with beta-catenin BibTex
2008-01-19 R-DME-209107 Further phosphorylation of APC by DCO BibTex
2008-01-19 R-NUL-209065 Human APC is further phosphorylated by Murine CKIepsilon BibTex
2008-01-19 R-DME-209049 Phosphorylation of AXN and APC by SGG BibTex
2008-01-19 R-NUL-209060 Human APC is further phosphorylated by Murine GSK3beta BibTex
2008-01-19 R-NUL-209146 Murine Axin1 is further phosphorylated by Human GSK3beta BibTex
2008-01-19 R-DME-209143 Phosphorylation of AXN and APC by DCO BibTex
2008-01-19 R-NUL-209132 Human APC is initially phosphorylated by Murine CKIepsilon BibTex
2008-01-19 R-DME-209133 Formation of the 'destruction complex' BibTex
2008-01-19 R-MMU-209059 Murine CKIepsilon binds to Murine Axin1 BibTex
2008-01-19 R-MMU-209148 Murine CKIalpha binds to Murine Axin1 BibTex
2008-01-19 R-DME-209081 Disassembly of the destabilised 'destruction complex' BibTex
2008-01-19 R-DME-209075 Destabilisation and degradation of AXN in the 'destruction complex' BibTex
2008-01-19 R-DME-209112 Inhibition of SGG results in the dephosphorylation of the 'destruction complex' by PP2A and release of ARM BibTex
2008-01-19 R-DME-209120 Membrane recruitment of DSH to FZ and AXN to phosphorylated ARR BibTex
2008-01-19 R-DME-209109 Further phosphorylation of ARM by SGG BibTex
2008-01-19 R-DME-209134 Phosphorylation of ARM by CKIalpha BibTex
2008-01-19 R-DME-209097 ARM binds to APC and AXN in the 'destruction complex' BibTex
2008-01-19 R-DME-209094 Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex' BibTex
2008-01-19 R-DME-209102 SLMB binds to phosphorylated ARM to form the 'destruction complex' BibTex
2008-01-19 R-DME-209082 Further phosphorylation of APC by SGG BibTex
2008-01-19 R-NUL-209144 Human APC is finally phosphorylated by Murine GSK3beta BibTex
2008-01-19 R-DME-209135 GISH further phosphorylates ARR in the receptor complex BibTex
2008-01-19 R-NUL-209104 Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex BibTex
2008-01-19 R-DME-209118 Membrane localised SGG phosphorylates ARR BibTex
2008-01-19 R-DME-209108 Membrane-bound GISH binds to ARR receptor complex BibTex
2008-01-19 R-DME-209074 WG, FZ and ARR bind to each other BibTex
2008-01-19 R-DME-209129 Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex BibTex
2008-01-19 R-DME-209322 In the absence of ARM, GRO binds to PAN and inhibits transcription BibTex
2008-01-19 R-DME-209303 LGS transports from the nucleus to the cytosol BibTex
2008-01-19 R-DME-209332 LGS dissociates from the PYGO complex BibTex
2008-01-19 R-DME-209371 LGS binds to ARM BibTex
2008-01-19 R-DME-209177 LGS:ARM complex transports from the cytosol to the nucleus BibTex
2008-01-19 R-DME-209297 PYGO binds to the LGS:ARM complex BibTex
2008-01-19 R-DME-209181 ARM displaces GRO and binds to PAN which activates transcription BibTex