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Tao Huang

 ORCID
Affiliation
National Institutes of Health
Reviewed Reactions (101)
Date Identifier Reaction Reference
2006-04-18 R-HSA-173488 The SMAD2/3:SMAD4 complex transfers to the nucleus BibTex
2006-04-18 R-HSA-170847 Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 BibTex
2006-04-18 R-HSA-170850 Phosphorylated SMAD2/3 dissociates from TGFBR BibTex
2006-04-18 R-HSA-170868 Activated type I receptor phosphorylates SMAD2/3 directly BibTex
2006-04-18 R-HSA-170835 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 BibTex
2006-04-18 R-HSA-170843 TGFBR2 phosphorylates TGFBR1 BibTex
2006-04-18 R-HSA-170846 TGFBR2 recruits TGFBR1 BibTex
2006-04-18 R-HSA-170861 Dimeric TGF-beta-1 binds to the receptor BibTex
2006-04-18 R-HSA-177107 Secretion and activation of the latent large complex of TGF-beta-1 BibTex
2006-04-18 R-HSA-170844 Latent TGF-beta-1 is cleaved by furin BibTex
2012-05-14 R-HSA-1484099 MYC trancscription is negatively regulated by SMAD2/3:SMAD4:RBL1:E2F4/5:DP1/2 complex BibTex
2012-05-14 R-HSA-2127257 SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 BibTex
2012-05-14 R-HSA-2187303 SMAD2/3:SMAD4:SP1 complex stimulates transcription of CDKN2B BibTex
2012-05-14 R-HSA-2187309 SMAD2/3:SMAD4 heterotrimer binds SP1 BibTex
2012-05-14 R-HSA-870477 Ubiquitinated SMAD4 translocates from the nucleus to the cytosol BibTex
2012-05-14 R-HSA-870449 TRIM33 monoubiquitinates SMAD4 BibTex
2012-05-14 R-HSA-870538 TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus BibTex
2012-05-14 R-HSA-870479 USP9X (FAM) binds to ubiquitinated SMAD4 BibTex
2012-05-14 R-HSA-2187395 Dephosphorylated SMAD2/3 translocates to the cytosol BibTex
2012-05-14 R-HSA-209055 PPM1A dephosphorylates nuclear SMAD2/3 BibTex
2012-05-14 R-HSA-2187388 PPM1A protein phosphatase binds phosphorylated SMAD2/3 BibTex
2012-05-14 R-HSA-2187330 PARP1 binds SMAD2/3:SMAD4 heterotrimer BibTex
2012-05-14 R-HSA-870437 USP9X (FAM) deubiquitinates SMAD4 BibTex
2012-05-14 R-HSA-2176491 NEDD4L binds phosphorylated linker region of SMAD2/3 BibTex
2012-05-14 R-HSA-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 BibTex
2006-04-18 R-HSA-173481 SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling BibTex
2012-05-14 R-HSA-2179274 SMURF2 binds SMAD3 phosphorylated in the linker region BibTex
2006-04-18 R-HSA-173545 Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling BibTex
2012-05-14 R-HSA-2179276 SMURF2 monoubiquitinates SMAD3 BibTex
2012-05-14 R-HSA-2186767 Degradation of ubiquitinated SKI/SKIL BibTex
2012-05-14 R-HSA-2186747 Ubiquitination of SKI/SKIL by RNF111/SMURF2 BibTex
2012-05-14 R-NUL-2186755 Ubiquitination of SKI/SKIL by Rnf111 BibTex
2012-05-14 R-HSA-2186741 SMAD2/3 activation induces binding of RNF111/SMURF2 to SKI/SKIL BibTex
2012-05-14 R-NUL-2186736 Rnf111 binds SKI/SKIL in complex with SMAD2/3:SMAD4 upon TGF-beta stimulation BibTex
2012-05-14 R-HSA-2186607 TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer BibTex
2012-05-14 R-HSA-2176503 Degradation of SMAD2/3:SMAD4 complex BibTex
2012-05-14 R-HSA-2176502 NEDD4L ubiquitinates SMAD2/3 BibTex
2012-05-14 R-HSA-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 BibTex
2012-05-14 R-HSA-2186785 RNF111 ubiquitinates SMAD7 BibTex
2012-05-14 R-NUL-2186775 Rnf111 ubiquitinates Smad7 BibTex
2012-05-14 R-HSA-2186771 RNF111 binds SMAD7 BibTex
2012-05-14 R-HSA-2106591 WWTR1:SMAD stimulates transcription of SMAD7 BibTex
2012-05-14 R-HSA-2106579 WWTR1:SMAD translocates to the nucleus BibTex
2012-05-14 R-HSA-2031355 WWTR1 binds SMAD2/3:SMAD4 heterotrimer BibTex
2012-05-14 R-HSA-2186643 MEN1 binds SMAD2/3:SMAD4 heterotrimer BibTex
2012-05-14 R-HSA-2106586 WWTR1:SMAD stimulates transcription of SERPINE1 while TGIF:SMAD and SMAD7 inhibit it BibTex
2012-05-14 R-HSA-2187293 SMAD2/3:SMAD4 complex positively regulates JUNB transcription BibTex
2012-05-14 R-HSA-2186780 Degradation of Ub-SMAD7 BibTex
2006-04-18 R-HSA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) BibTex
2012-05-14 R-HSA-2169046 Degradation of TGF-beta receptor complex BibTex
2012-05-14 R-HSA-2169050 SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 BibTex
2012-05-14 R-NUL-2176393 SMURF2 ubiquitinates Smad7 and phosphorylated TGFBR1 BibTex
2012-05-14 R-NUL-2176427 NEDD4L ubiquitinates Smad7 and TGFBR1 BibTex
2012-05-14 R-NUL-2176396 SMURF1 ubiquitinates Smad7 and phosphorylated TGFBR1 BibTex
2012-05-14 R-HSA-178218 SMAD7:SMURF complex binds to phosphorylated TGFBR1 BibTex
2012-05-14 R-NUL-2169043 Smad7:SMURF2 binds phosphorylated TGFBR1 BibTex
2012-05-14 R-NUL-2169036 Smad7:SMURF1 binds phosphorylated TGFBR1 BibTex
2012-05-14 R-NUL-2176431 Smad7 recruits NEDD4L to activated TGF-beta receptor complex BibTex
2012-05-14 R-HSA-2176417 SMAD7:NEDD4L complex translocates to the cytosol BibTex
2012-05-14 R-NUL-2176428 Translocation of Smad7:NEDD4L complex to the cytosol BibTex
2012-05-14 R-HSA-2176416 NEDD4L ubiquitin ligase binds SMAD7 BibTex
2012-05-14 R-NUL-2176430 NEDD4L binds Smad7 BibTex
2012-05-14 R-HSA-178215 SMAD7:SMURF1 complex is exported to the cytosol BibTex
2012-05-14 R-NUL-2169016 Smad7:SMURF1 complex translocates to the cytosol BibTex
2012-05-14 R-HSA-2167924 SMAD7:SMURF1 complex binds XPO1 (CRM1) BibTex
2012-05-14 R-NUL-2169012 Smad7:SMURF1 complex binds XPO1 (CRM1) BibTex
2012-05-14 R-HSA-2167917 SMAD7 binds to SMURF1 BibTex
2012-05-14 R-NUL-2169004 Smad7 binds SMURF1 BibTex
2012-05-14 R-HSA-2167876 SMAD7:SMURF2 complex translocates to the cytosol BibTex
2012-05-14 R-NUL-2167888 Smad7:SMURF2 complex translocates to the cytosol BibTex
2012-05-14 R-HSA-178208 SMAD7 binds to SMURF2 BibTex
2006-04-18 R-HSA-173542 SMURF2 ubiquitinates SMAD2 BibTex
2012-05-14 R-HSA-2176445 SMURF2 binds SMAD2 BibTex
2012-05-14 R-HSA-2187355 PMEPA1 sequesters phosphorylated SMAD2/3 BibTex
2012-05-14 R-HSA-2187401 MTMR4 dephosphorylates SMAD2/3 BibTex
2012-05-14 R-HSA-2187405 MTMR4 binds phosphorylated SMAD2/3 BibTex
2012-05-14 R-HSA-2176452 Degradation of ubiquitinated SMAD2 BibTex
2012-05-14 R-HSA-2128994 STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 BibTex
2012-05-14 R-HSA-2127562 STRAP binds phosphorylated TGF-beta receptor complex BibTex
2012-05-14 R-NUL-2128982 Strap binds phosphorylated TGF-beta receptor complex BibTex
2012-05-14 R-HSA-2187358 PMEPA1 sequesters unphosphorylated SMAD2/3 BibTex
2012-05-14 R-HSA-2187375 SMAD3 binds STUB1 (CHIP) BibTex
2012-05-14 R-HSA-2187382 Degradation of ubiquitinated SMAD3 BibTex
2012-05-14 R-HSA-2187368 STUB1 (CHIP) ubiquitinates SMAD3 BibTex
2012-05-14 R-HSA-178178 PP1 dephosphorylates TGFBR1 BibTex
2012-05-14 R-NUL-2167872 PP1CC dephosphorylates TGFBR1 BibTex
2012-05-14 R-HSA-178189 SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR BibTex
2012-05-14 R-NUL-2167890 Smad7 recruits GADD34:PP1CC to phosphorylated TGF-beta receptor complex BibTex
2012-05-14 R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 BibTex
2012-05-14 R-NUL-2179313 Uchl5 deubiquitinates TGFBR1 BibTex
2012-05-14 R-HSA-2179293 UCHL5 binds SMAD7 in complex with ubiquitinated TGFBR1 BibTex
2012-05-14 R-NUL-2179307 Uchl5 is recruited to TGF-beta receptor complex through Smad7 BibTex
2012-05-14 R-HSA-2160931 Disassembly of tight junctions BibTex
2012-05-14 R-HSA-2160935 SMURF1 ubiquitinates RHOA BibTex
2012-05-14 R-HSA-2160932 SMURF1 binds phosphorylated PARD6A BibTex
2012-05-14 R-HSA-2134532 TGFBR2 phosphorylates TGFBR1 and PARD6A BibTex
2012-05-14 R-NUL-2161165 TGFBR2 phosphorylates Pard6a BibTex
2012-05-14 R-HSA-2134519 TGFBR2 is recruited to tight junctions after TGF-beta stimulation BibTex
2012-05-14 R-NUL-2161160 TGFBR2 is recruited to tight junctions-associated, Pard6a-bound, TGFBR1 after TGF-beta stimulation BibTex
2012-05-14 R-HSA-2134506 TGFBR1 is recruited to tight junctions by PARD6A BibTex
2012-05-14 R-NUL-2161147 TGFBR1 is recruited to tight junction by binding Pard6a BibTex
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