Sean Egan

 ORCID
Affiliation
The Hospital for Sick Children, University of Toronto, Department of Molecular Genetics
Authored Pathways (6/6)
Date Identifier Pathway Reference
2011-11-14 R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus BibTex
2011-11-14 R-HSA-1912408 Pre-NOTCH Transcription and Translation BibTex
2011-11-14 R-HSA-1912422 Pre-NOTCH Expression and Processing BibTex
2011-11-14 R-HSA-1912399 Pre-NOTCH Processing in the Endoplasmic Reticulum BibTex
2011-11-14 R-HSA-1980143 Signaling by NOTCH1 BibTex
2011-11-14 R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription BibTex
Authored Reactions (15/93)
Date Identifier Reaction Reference
2012-05-14 R-MMU-2247925 Notch1 gene transcription BibTex
2012-05-14 R-MMU-4395232 Ccnd1:Crebbp binds Notch1 promoter BibTex
2011-11-14 R-HSA-1980067 NOTCH1 stimulates MYC transcription BibTex
2011-11-14 R-HSA-4396371 NOTCH1 Coactivator Complex binds MYC promoter BibTex
2011-11-14 R-HSA-1912394 NICD1 in complex with RBPJ (CSL) recruits MAML BibTex
2011-11-14 R-HSA-1912388 NICD1 displaces co-repressor complex from RBPJ (CSL) BibTex
2011-11-14 R-NUL-2064264 NICD1 displaces NCOR co-repressor complex from CSL BibTex
2011-11-14 R-NUL-2063915 ADAM17 cleaves Notch1 at S2 BibTex
2011-11-14 R-HSA-1980074 Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 BibTex
2011-11-14 R-MMU-2032750 Sel1l negatively regulates Pre-Notch exit from endoplasmic reticulum BibTex
2011-11-14 R-DME-2032746 Rab6 positively regulates Notch trafficking through Golgi BibTex
2011-11-14 R-DME-1984022 Endoplasmic reticulum calcium ATPases positively regulate Notch precursor trafficking BibTex
2011-11-14 R-HSA-1912353 Glucosylation of Pre-NOTCH by POGLUT1 BibTex
2011-11-14 R-MMU-2023179 Glucosylation of Pre-Notch by Poglut1 BibTex
2011-11-14 R-HSA-1912349 Fucosylation of Pre-NOTCH by POFUT1 BibTex