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Yulu Cherry Liu

Reviewed Reactions (106)
Date Identifier Reaction Reference
2014-11-09 R-HSA-5635850 GLI1 binds HHIP gene, PTCH2 gene and BOC gene promoters BibTex
2014-11-09 R-HSA-5635848 GLI proteins bind PTCH1 gene BibTex
2014-11-09 R-HSA-5635868 ub-GLI is degraded by the proteasome BibTex
2014-11-09 R-HSA-5635864 NUMB:ITCH ubiquitinates GLI1 BibTex
2014-11-09 R-HSA-5635854 GLI2,3 are degraded by the proteasome BibTex
2014-11-09 R-HSA-445448 HHIP binds Hedgehog BibTex
2014-11-09 R-HSA-5632653 Hh-Npp binds BOC:PTCH1 BibTex
2014-11-09 R-MMU-5632654 Shh binds Boc:Ptch1 BibTex
2014-11-09 R-HSA-5632649 Hh-Npp binds GAS1 and PTCH BibTex
2014-11-09 R-HSA-5632652 Hh-Npp binds CDON and PTCH BibTex
2014-11-09 R-HSA-5635845 GLI proteins bind CDC73 BibTex
2014-11-09 R-HSA-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 BibTex
2014-11-09 R-HSA-5633051 EFCAB7:IQCE binds EVC2:EVC BibTex
2014-11-09 R-HSA-5632679 EVC2:EVC binds p-SMO BibTex
2014-11-09 R-HSA-5633040 CSNK1A1 and ADRBK1 dissociate from p-SMO dimer BibTex
2014-11-09 R-HSA-5632672 ADRBK1 phosphorylates SMO dimer BibTex
2014-11-09 R-HSA-5632674 ADRBK1 binds phosphorylated SMO dimer BibTex
2014-11-09 R-HSA-5632670 CSNK1A1 phosphorylates SMO dimer BibTex
2014-11-09 R-HSA-5632671 CSNK1A1 binds SMO dimer BibTex
2014-11-09 R-MMU-5632665 Adrbk1 phosphorylates Smo dimer BibTex
2014-11-09 R-MMU-5632663 Adrbk1 binds pS592, S594, T597, S599 Smo dimer:Csnk1a1 BibTex
2014-11-09 R-MMU-5632661 Csnk1a1 phosphorylates Smo dimer BibTex
2014-11-09 R-MMU-5632658 Csnk1a1 binds Smo dimer BibTex
2014-11-09 R-MMU-5633169 Evc2:Evc binds Smo BibTex
2014-11-09 R-HSA-5632668 SMO translocates to the cilium BibTex
2014-11-09 R-HSA-5632667 SMO dimer binds ARRB and KIF3A BibTex
2014-11-09 R-MMU-5632657 Smo dimer binds Arrb and Kif3a BibTex
2014-11-09 R-HSA-5635855 phosphorylated GLI proteins bind SPOP:CUL3:RBX1 BibTex
2014-11-09 R-HSA-5632677 PTCH is internalized BibTex
2014-11-09 R-HSA-5635865 SMURF1/2 dissociates from ub-PTCH1 BibTex
2014-11-09 R-HSA-5632648 SMURF1/2 ubiquitinates PTCH1 BibTex
2014-11-09 R-HSA-5632646 SMURF1/2 bind PTCH1 BibTex
2014-11-09 R-MMU-5632644 Smurf1/2 ubiquitinates Ptch1 BibTex
2014-11-09 R-MMU-5632642 Smurf1/2 bind Ptch1 BibTex
2014-11-09 R-HSA-5635861 NUMB:ITCH binds GLI1 BibTex
2014-11-09 R-HSA-5635853 Hh-dependent expression of GLI1 gene BibTex
2014-11-09 R-HSA-5635846 GLI proteins bind GLI1 gene BibTex
2014-11-09 R-HSA-5635102 GPR161 is internalized BibTex
2014-11-09 R-HSA-5635841 GLI proteins are phosphorylated BibTex
2014-11-09 R-HSA-5635843 GLI translocates to the nucleus BibTex
2014-11-09 R-HSA-5635842 ULK3 phosphorylates GLI BibTex
2014-11-09 R-HSA-5635859 GLI:SUFU dissociates BibTex
2014-11-09 R-HSA-5635860 GLI:SUFU translocates to the ciliary tip in response to Hh signaling BibTex
2014-11-09 R-HSA-5635839 ULK3:SUFU dissociates BibTex
2014-08-01 R-HSA-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules BibTex
2014-08-01 R-HSA-5612510 Expression of PTCH1 is repressed by GLI3R in the absence of Hh signaling BibTex
2014-08-01 R-HSA-5610757 GLI2 is degraded by the proteasome BibTex
2014-08-01 R-HSA-5610745 SCF(beta-TrCP) ubiquitinates p-GLI2 BibTex
2014-08-01 R-HSA-5610730 GSK3 phosphorylates p-GLI2 BibTex
2014-08-01 R-HSA-5610718 CK1 phosphorylates p-GLI2 BibTex
2014-08-01 R-HSA-5610717 PKA phosphorylates GLI2 BibTex
2014-08-01 R-MMU-5610710 Pka phosphorylates Gli2 BibTex
2014-08-01 R-NUL-5610715 CK1 phosphorylates p-Gli2 BibTex
2014-08-01 R-NUL-5610714 GSK3 phosphorylates p-Gli2 BibTex
2014-08-01 R-NUL-5610711 SCF(beta-TrCP) ubiquitinates p-Gli2 BibTex
2014-08-01 R-NUL-5610751 Gli2is degraded by the proteasome BibTex
2014-08-01 R-HSA-5612508 GLI3R binds the PTCH1 promoter BibTex
2014-08-01 R-HSA-5610763 PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal BibTex
2014-08-01 R-HSA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip BibTex
2014-08-01 R-HSA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH BibTex
2014-08-01 R-HSA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP BibTex
2014-08-01 R-HSA-5610737 NUMB:ITCH bind and ubiquitnate GLI1 BibTex
2014-08-01 R-HSA-5610742 SCF(beta-TrCP) ubiquitinates p-GLI1 BibTex
2014-08-01 R-HSA-5610741 PKA phosphorylates GLI1 BibTex
2014-08-01 R-NUL-5610740 Pka phosphorylates GLI1 BibTex
2014-08-01 R-HSA-5610735 NUMB binds ITCH BibTex
2014-08-01 R-HSA-5610723 GLI proteins bind SUFU BibTex
2014-08-01 R-HSA-5617412 Expression of GLI1 is repressed by GLI3R in the absence of Hh signaling BibTex
2014-08-01 R-HSA-5617408 GLI3R binds the GLI1 promoter BibTex
2014-08-01 R-HSA-5617413 Expression of GLI2 is repressed by GLI3R in the absence of Hh signaling BibTex
2014-08-01 R-HSA-5617410 GLI3R binds the GLI2 promoter BibTex
2014-08-01 R-HSA-5610752 GLI3R translocates to the nucleus BibTex
2014-08-01 R-HSA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor BibTex
2014-08-01 R-HSA-5610746 SCF(beta-TrCP) ubiquitinates p-GLI3 BibTex
2014-08-01 R-HSA-5610732 GSK3 phosphorylates p-GLI3 BibTex
2014-08-01 R-HSA-5610722 CK1 phosphorylates p-GLI3 BibTex
2014-08-01 R-HSA-5610720 PKA phosphorylates GLI3 BibTex
2014-08-01 R-HSA-5610749 cAMP dissociates PKA, promoting GLI processing BibTex
2014-08-01 R-HSA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner BibTex
2014-08-01 R-HSA-5610725 TULP3 is required for GPR161 localization in the cilium BibTex
2014-08-01 R-HSA-5610726 The IFT-A complex recruits TULP3 BibTex
2014-08-01 R-HSA-5610766 The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base BibTex
2014-05-16 R-HSA-5483229 HHAT G287V doesn't palmitoylate Hh-Np BibTex
2014-05-16 R-HSA-5362793 Hh-Np is cleaved by ADAM17 to promote ligand shedding BibTex
2014-05-16 R-NUL-5362792 Shh is released from the plasma membrane by ADAM17-mediated cleavage BibTex
2014-05-16 R-HSA-5362553 NOTUM releases Hh-Np:GPC5 from the plasma membrane BibTex
2014-05-16 R-HSA-5362427 Hh-Np binds GPC5 BibTex
2014-05-16 R-HSA-5362551 Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling BibTex
2014-05-16 R-HSA-5362422 Hh-Np binds to DISP2 BibTex
2014-05-16 R-NUL-5362406 mouse Disp2 binds SHH N-terminal fragment BibTex
2014-05-16 R-HSA-5362549 Hh-Np traffics to the plasma membrane BibTex
2014-05-16 R-HSA-5358343 HHAT palmitoylates Hh N-terminal fragment BibTex
2014-05-16 R-HSA-5362448 Hh C-terminal fragments are degraded by the proteasome BibTex
2014-05-16 R-HSA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol BibTex
2014-05-16 R-HSA-5362412 SYVN1 ubiquitinates Hh C-terminal fragments BibTex
2014-05-16 R-HSA-5362441 C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane BibTex
2014-05-16 R-HSA-5362437 C-terminal Hh fragments are bound by lectins BibTex
2014-05-16 R-HSA-5358460 HPE SHH variants don't undergo autoproteolytic cleavage BibTex
2014-05-16 R-HSA-5358340 Autoproteolytic cleavage of Hh precursors BibTex
2014-05-16 R-HSA-5358336 P4HB forms mixed disulphides with Hh precursors BibTex
2014-05-16 R-HSA-5362386 Glycosylation of Hh BibTex
2014-05-16 R-HSA-5387392 processing defective Hh variants are degraded by the proteasome BibTex
2014-05-16 R-HSA-5387389 Hh processing variants are translocated to the cytosol in a VCP-dependent manner BibTex
2014-05-16 R-HSA-5483238 Hh processing variants are ubiquitinated BibTex
2014-05-16 R-HSA-5387386 Hh processing variants are recruited to SEL1:SYVN at the ER membrane BibTex
2014-05-16 R-HSA-5362450 Hh processing variants bind lectins BibTex