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Emmanouil Metzakopian

 ORCID
https://orcid.org/0000-0003-2893-9741
Reviewed Reactions (87)
Date Identifier Reaction Reference
2019-10-30 R-HSA-9664867 NBR1 binds MAP1LC3B BibTex
2019-10-30 R-HSA-9664855 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 BibTex
2019-10-30 R-HSA-9664880 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 BibTex
2019-10-30 R-HSA-9664881 NBR1 binds ATM:Ub-p-PEX5:SQSTM1 BibTex
2019-10-30 R-HSA-9664871 NBR1 translocates from cytosol to perixosomal membrane BibTex
2019-10-30 R-MMU-9666410 Nbr1 translocates from cytosol to perixosomal membrane BibTex
2019-10-30 R-HSA-9664892 SQSTM1 binds ATM dimer:Ub-p-PEX5 BibTex
2019-10-30 R-HSA-9674131 USP30 binds ATM dimer:Ub-p-PEX5 BibTex
2019-10-30 R-HSA-9664888 ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 BibTex
2019-10-30 R-HSA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 BibTex
2019-10-30 R-HSA-9664862 ATM dimer:PEX5 phosphorylates PEX5 BibTex
2019-10-30 R-HSA-9664879 ATM:PEX5 binds ATM BibTex
2019-10-30 R-HSA-9664883 ATM:PEX5 translocates from cytosol to peroxisomal membrane BibTex
2019-10-30 R-HSA-9664850 ATM binds PEX5 BibTex
2019-05-24 R-HSA-9646685 Aggresome dissociates from dynein and microtubule BibTex
2019-05-24 R-HSA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome BibTex
2019-05-24 R-HSA-9646383 Dynein motors transport misfolded proteins BibTex
2019-05-24 R-HSA-9646390 Misfolded proteins:HDAC6:Dynein motor binds microtubule BibTex
2019-05-24 R-HSA-9646348 PolyUb-Misfolded Proteins:HDAC6 bind dynein motor BibTex
2019-05-24 R-HSA-9646354 PolyUb-Misfolded Proteins:HDAC6 dissociate from complex BibTex
2019-05-24 R-HSA-9646347 PolyUb-misfolded proteins bind VCP:HDAC6:HSP90:HSF1 BibTex
2019-05-24 R-HSA-9641109 PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 BibTex
2019-05-24 R-HSA-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins BibTex
2019-05-24 R-HSA-9641111 Parkin transfers Ub to misfolded proteins BibTex
2019-05-24 R-HSA-9641096 Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub BibTex
2019-05-24 R-HSA-9640114 Misfolded proteins translocate from cilium to cytosol BibTex
2019-05-24 R-HSA-9639698 ROS positively regulates misfolding of cilia proteins BibTex
2019-05-24 R-MMU-9640117 Misfolded proteins translocate from cilium to cytosol BibTex
2019-05-24 R-MMU-9639715 ROS positively regulates misfolding of cilia proteins BibTex
2019-05-24 R-HSA-9641089 Parkin binds Ub:UBE2N:UBE2V1 BibTex
2019-05-24 R-HSA-9640480 E2 enzyme UBE2N:UBE2V1 binds ubiquitin BibTex
2019-05-24 R-SCE-9640470 E2 enzyme MMS2:UBC13 binds ubiquitin BibTex
2019-05-24 R-MMU-9646359 PolyUb-Misfolded Proteins:Hdac6 dissociate from complex BibTex
2019-05-24 R-MMU-9646345 Ubiquitin binds Vcp:Hdac6:Hsp90:Hsf1 BibTex
2019-05-24 R-MMU-9646393 Hdac6 binds microtubule BibTex
2019-05-24 R-NUL-9646387 Dynein motors transport misfolded proteins BibTex
2019-02-22 R-HSA-9631065 Substrate translocates into late endosomal lumen BibTex
2019-02-22 R-HSA-9631068 HSPA8:substrate binds late endosomal phospholipids BibTex
2019-02-22 R-MMU-9631080 Substrate translocates into late endosomal lumen BibTex
2019-02-22 R-MMU-9631076 Hspa8:substrate binds late endosomal phospholipids BibTex
2019-02-22 R-RNO-9626037 p-Gfap binds Eef1a1 BibTex
2019-02-22 R-RNO-9626032 Eef1a1 dissociates from p-Gfap BibTex
2019-02-22 R-HSA-9626046 p-GFAP binds EEF1A1 BibTex
2019-02-22 R-HSA-9626034 EEF1A1 dissociates from p-GFAP BibTex
2019-02-22 R-RNO-9626036 Eef1a1 binds GTP BibTex
2019-02-22 R-RNO-9626064 Eef1a1:GTP translocates from lysosomal membrane to cytosol BibTex
2019-02-22 R-HSA-9626038 EEF1A1 binds GTP BibTex
2019-02-22 R-HSA-9626067 EEF1A1:GTP translocates from lysosomal membrane to cytosol BibTex
2019-02-22 R-RNO-9626236 Hspa8 dissociates from Lamp2 BibTex
2019-02-22 R-RNO-9626275 Hsp90 dissociates from Lamp2 BibTex
2019-02-22 R-RNO-9615712 Hspa8 binds Rnase1 BibTex
2019-02-22 R-RNO-9620205 Hspa8:Rnase1 binds Lamp2a BibTex
2019-02-22 R-RNO-9622832 Hspa8 dissociates from Lamp2a-bound substrate BibTex
2019-02-22 R-RNO-9622851 Substrate:Lamp2a binds Hsp90 BibTex
2019-02-22 R-RNO-9624154 Substrate:Lamp2a:Hsp90 polymerizes BibTex
2019-02-22 R-RNO-9625183 Gfap binds Lamp2 multimer BibTex
2019-02-22 R-RNO-9625173 Unfolded substrate in Lamp2 multimeric complex binds Hspa8 BibTex
2019-02-22 R-RNO-9625160 Hspa8 transports unfolded substrate to lysosomal lumen for degradation BibTex
2019-02-22 R-RNO-9626028 Hspa8:Substrate dissociates from Lamp2 multimer BibTex
2019-02-22 R-RNO-9626030 p-Gfap binds Gfap in Lamp2 multimer BibTex
2019-02-22 R-RNO-9626250 p-Gfap:Gfap dissociates from Lamp2 multimer BibTex
2019-02-22 R-RNO-9626239 Hspa8 binds Lamp2 multimers BibTex
2019-02-22 R-RNO-9626254 Hspa8:Lamp2 multimers depolymerizes to monomers BibTex
2019-02-22 R-HSA-9626235 HSPA8 dissociates from LAMP2a BibTex
2019-02-22 R-HSA-9626276 HSP90 dissociates from LAMP2a BibTex
2019-02-22 R-MMU-9613507 Plins:Hspa8 binds Prkaa2 BibTex
2019-02-22 R-MMU-9613545 Prkaa2 phosphorylates Plins BibTex
2019-02-22 R-MMU-9613670 p-Plins translocate from lipid droplet surface to cytosol BibTex
2019-02-22 R-RNO-9613356 Plins bind Hspa8 BibTex
2019-02-22 R-HSA-9613352 PLINs bind HSPA8 BibTex
2019-02-22 R-HSA-9613513 PLINs:HSPA8 binds PRKAA2 BibTex
2019-02-22 R-HSA-9613530 PRKAA2 phosphorylates PLINs BibTex
2019-02-22 R-HSA-9613565 PRKAA2 dissociate from p-PLINs:HSPA8 BibTex
2019-02-22 R-HSA-9613666 p-PLINs translocate from lipid droplet surface to cytosol BibTex
2019-02-22 R-HSA-9615721 HSPA8 binds substrate BibTex
2019-02-22 R-HSA-9620197 HSPA8:Substrate binds LAMP2a BibTex
2019-02-22 R-HSA-9622840 HSPA8 dissociates from LAMP2A-bound substrate BibTex
2019-02-22 R-HSA-9622831 Substrate:LAMP2a binds HSP90 BibTex
2019-02-22 R-HSA-9624158 Substrate:LAMP2a:HSP90 polymerizes BibTex
2019-02-22 R-HSA-9625197 GFAP binds LAMP2a multimer BibTex
2019-02-22 R-HSA-9625196 Unfolded substrate in LAMP2a multimeric complex binds HSPA8 BibTex
2019-02-22 R-HSA-9625188 HSPA8 transports unfolded substrate to lysosomal lumen for degradation BibTex
2019-02-22 R-HSA-9626060 HSPA8:Substrate dissociates from LAMP2a multimer BibTex
2019-02-22 R-HSA-9626039 pGFAP binds GFAP in LAMP2a multimer BibTex
2019-02-22 R-HSA-9626242 p-GFAP:GFAP dissociates from LAMP2a multimer BibTex
2019-02-22 R-HSA-9626253 HSPA8 binds LAMP2a multimers BibTex
2019-02-22 R-HSA-9626256 HSPA8:LAMP2a multimers depolymerizes to monomers BibTex
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