Sisira Kadambat Nair

 ORCID
https://orcid.org/0000-0003-0693-9994
Affiliation
Princess Margaret Cancer Centre, Princess Margaret Hospital
Reviewed Pathways (6/6)
Date Identifier Pathway Reference
2025-09-16 R-HSA-8874177 ATF6B (ATF6-beta) activates chaperones BibTex
2021-11-02 R-HSA-9754119 Drug-mediated inhibition of CDK4/CDK6 activity BibTex
2021-08-05 R-HSA-9734091 Drug-mediated inhibition of MET activation BibTex
2021-07-28 R-HSA-9729902 Reversible DNA damage induced by alkylating chemotherapeutic drugs BibTex
2021-07-28 R-HSA-9730737 Alkylating DNA damage induced by chemotherapeutic drugs BibTex
2021-07-28 R-HSA-9750126 Drug-induced formation of DNA interstrand crosslinks BibTex
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Reviewed Reactions (15/26)
Date Identifier Reaction Reference
2025-09-16 R-HSA-8874137 ATF6B (ATF6-beta) translocates from the cytosol to the nucleus BibTex
2025-09-16 R-HSA-8874122 MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) BibTex
2025-09-16 R-HSA-8874145 MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) BibTex
2025-09-16 R-HSA-8874138 ATF6B (ATF6-beta) translocates from the endoplasmic reticulum to the Golgi BibTex
2025-09-16 R-HSA-8874162 ATF6B:HSPA5 (ATF6-beta:BiP) dissociates and HSPA5 binds unfolded protein BibTex
2021-11-02 R-HSA-9754130 CDK4 inhibitors bind CDK4 BibTex
2021-11-02 R-HSA-9754129 CDK6 inhibitors bind CDK6 BibTex
2021-11-02 R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes BibTex
2021-08-05 R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET BibTex
2021-08-05 R-HSA-9734070 Anti-MET recombinant therapeutic antibodies bind MET BibTex
2021-08-05 R-HSA-6806974 MET dimers autophosphorylate BibTex
2021-08-05 R-HSA-6800298 HGF dimer binds MET BibTex
2021-07-28 R-HSA-9732692 Triazenes produce DNA damage in the form of O6-methylguanine BibTex
2021-07-28 R-MMU-9749883 Temozolomide produces DNA damage in the form of O6-methylguanine in mouse dsDNA BibTex
2021-07-28 R-RNO-9732711 Streptozocin produces DNA damage in the form of O6-methylguanine in rat dsDNA BibTex
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