Bernard de Bono

 ORCID
https://orcid.org/0000-0003-0638-5274
Project
Reactome
Affiliation
EBI
Authored Pathways (68/68)
Date Identifier Pathway Reference
2024-03-06 R-HSA-168898 Toll-like Receptor Cascades BibTex
2011-05-22 R-HSA-1280218 Adaptive Immune System BibTex
2008-03-05 R-HSA-210993 Tie2 Signaling BibTex
2008-02-26 R-HSA-373753 Nephrin family interactions BibTex
2008-02-26 R-HSA-210990 PECAM1 interactions BibTex
2008-02-26 R-HSA-210991 Basigin interactions BibTex
2008-02-26 R-HSA-373756 SDK interactions BibTex
2008-01-24 R-HSA-202403 TCR signaling BibTex
2008-01-24 R-HSA-202433 Generation of second messenger molecules BibTex
2008-01-24 R-HSA-202424 Downstream TCR signaling BibTex
2008-01-24 R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains BibTex
2008-01-24 R-HSA-202430 Translocation of ZAP-70 to Immunological synapse BibTex
2007-07-08 R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell BibTex
2007-01-10 R-HSA-190236 Signaling by FGFR BibTex
2007-01-10 R-HSA-5654743 Signaling by FGFR4 BibTex
2007-01-10 R-HSA-190322 FGFR4 ligand binding and activation BibTex
2007-01-10 R-HSA-5654716 Downstream signaling of activated FGFR4 BibTex
2007-01-10 R-HSA-5654720 PI-3K cascade:FGFR4 BibTex
2007-01-10 R-HSA-5654719 SHC-mediated cascade:FGFR4 BibTex
2007-01-10 R-HSA-5654228 Phospholipase C-mediated cascade; FGFR4 BibTex
2007-01-10 R-HSA-5654712 FRS-mediated FGFR4 signaling BibTex
2007-01-10 R-HSA-5654738 Signaling by FGFR2 BibTex
2007-01-10 R-HSA-190241 FGFR2 ligand binding and activation BibTex
2007-01-10 R-HSA-190375 FGFR2c ligand binding and activation BibTex
2007-01-10 R-HSA-190377 FGFR2b ligand binding and activation BibTex
2007-01-10 R-HSA-5654696 Downstream signaling of activated FGFR2 BibTex
2007-01-10 R-HSA-5654221 Phospholipase C-mediated cascade; FGFR2 BibTex
2007-01-10 R-HSA-5654695 PI-3K cascade:FGFR2 BibTex
2007-01-10 R-HSA-5654700 FRS-mediated FGFR2 signaling BibTex
2007-01-10 R-HSA-5654699 SHC-mediated cascade:FGFR2 BibTex
2007-01-10 R-HSA-5654736 Signaling by FGFR1 BibTex
2007-01-10 R-HSA-5654687 Downstream signaling of activated FGFR1 BibTex
2007-01-10 R-HSA-5654689 PI-3K cascade:FGFR1 BibTex
2007-01-10 R-HSA-5654688 SHC-mediated cascade:FGFR1 BibTex
2007-01-10 R-HSA-5654693 FRS-mediated FGFR1 signaling BibTex
2007-01-10 R-HSA-5654219 Phospholipase C-mediated cascade: FGFR1 BibTex
2007-01-10 R-HSA-190242 FGFR1 ligand binding and activation BibTex
2007-01-10 R-HSA-190374 FGFR1c and Klotho ligand binding and activation BibTex
2007-01-10 R-HSA-190373 FGFR1c ligand binding and activation BibTex
2007-01-10 R-HSA-190370 FGFR1b ligand binding and activation BibTex
2007-01-10 R-HSA-5654741 Signaling by FGFR3 BibTex
2007-01-10 R-HSA-5654708 Downstream signaling of activated FGFR3 BibTex
2007-01-10 R-HSA-5654710 PI-3K cascade:FGFR3 BibTex
2007-01-10 R-HSA-5654706 FRS-mediated FGFR3 signaling BibTex
2007-01-10 R-HSA-5654704 SHC-mediated cascade:FGFR3 BibTex
2007-01-10 R-HSA-5654227 Phospholipase C-mediated cascade; FGFR3 BibTex
2007-01-10 R-HSA-190239 FGFR3 ligand binding and activation BibTex
2007-01-10 R-HSA-190371 FGFR3b ligand binding and activation BibTex
2007-01-10 R-HSA-190372 FGFR3c ligand binding and activation BibTex
2006-03-30 R-HSA-168256 Immune System BibTex
2005-08-16 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade BibTex
2005-08-16 R-HSA-166166 MyD88-independent TLR4 cascade BibTex
2005-08-16 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane BibTex
2005-08-16 R-HSA-166020 Transfer of LPS from LBP carrier to CD14 BibTex
2005-08-16 R-HSA-975155 MyD88 dependent cascade initiated on endosome BibTex
2004-08-13 R-HSA-76002 Platelet activation, signaling and aggregation BibTex
2004-08-13 R-HSA-76009 Platelet Aggregation (Plug Formation) BibTex
2004-08-13 R-HSA-76005 Response to elevated platelet cytosolic Ca2+ BibTex
2004-08-13 R-HSA-75892 Platelet Adhesion to exposed collagen BibTex
2004-08-04 R-HSA-166658 Complement cascade BibTex
2004-08-04 R-HSA-166665 Terminal pathway of complement BibTex
2004-08-04 R-HSA-166663 Initial triggering of complement BibTex
2004-08-04 R-HSA-173736 Alternative complement activation BibTex
2004-08-04 R-HSA-166786 Creation of C4 and C2 activators BibTex
2004-08-04 R-HSA-173623 Classical antibody-mediated complement activation BibTex
2004-08-04 R-HSA-166662 Lectin pathway of complement activation BibTex
2004-08-04 R-HSA-174577 Activation of C3 and C5 BibTex
2004-01-22 R-HSA-109582 Hemostasis BibTex
Authored Reactions (227/227)
Date Identifier Reaction Reference
2008-03-05 R-HSA-204850 Interaction of Tie2 and Dok-2 BibTex
2008-03-05 R-HSA-204773 Interaction of Tie2 and Grb7 BibTex
2008-03-05 R-HSA-204798 Interaction of Tie2 and p85 of PI3K BibTex
2008-03-05 R-HSA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) BibTex
2008-03-05 R-HSA-204861 Interaction of Tie2 and Shc1 BibTex
2008-03-05 R-HSA-204813 Interaction of Tie2 and Grb14 BibTex
2008-03-05 R-HSA-204863 Interaction of Tie2 with Ang2 BibTex
2008-03-05 R-HSA-204824 Interaction of Tie2 and Ang4 BibTex
2008-03-05 R-HSA-204873 Interaction of Tie2 and Shp2 BibTex
2008-03-05 R-MMU-211119 Trans-phosphorylation of Tie2 BibTex
2008-03-05 R-HSA-204779 Interaction of Tie2 with Ang1 BibTex
2008-03-05 R-HSA-210881 Dimerization of Tie2/Ang1 complex BibTex
2008-03-05 R-HSA-210872 Trans-phosphorylation of Tie2 BibTex
2008-03-05 R-HSA-204871 Interaction of Tie2 and Grb2 BibTex
2008-03-05 R-HSA-210974 Interaction of SOS-1 to Tie2 bound Grb2 BibTex
2008-02-26 R-RNO-451396 Nephrin binds Cask BibTex
2008-02-26 R-HSA-373722 Nephrin binds CASK BibTex
2008-02-26 R-HSA-451377 Interaction of IQGAP1 with nephrin BibTex
2008-02-26 R-HSA-373724 Nephrin binds NCK BibTex
2008-02-26 R-HSA-532603 Nephrin mediated activation of N-WASP BibTex
2008-02-26 R-RNO-451384 Interaction of nephrin with adherens junction-associated proteins BibTex
2008-02-26 R-HSA-451403 Interaction of nephrin with adherens junction-associated proteins BibTex
2008-02-26 R-HSA-451757 Heterodimerization of nephrin and KIRREL2, KIRREL3 BibTex
2008-02-26 R-RNO-451755 p85 associates with both p-Nephrin and CD2AP BibTex
2008-02-26 R-MMU-451756 Nephrin binds CD2AP BibTex
2008-02-26 R-HSA-373727 Nephrin binds CD2AP BibTex
2008-02-26 R-HSA-451758 p85 associates with both p-Nephrin and CD2AP BibTex
2008-02-26 R-HSA-373714 Cis-Heterodimerization of nephrin and KIRREL BibTex
2008-02-26 R-HSA-8981534 Nephrin dimer:KIRREL binds FYN BibTex
2008-02-26 R-HSA-373747 Phosphorylation of nephrin by FYN BibTex
2008-02-26 R-HSA-373734 Nephrin interacts with Podocin BibTex
2008-02-26 R-HSA-373732 Nephrin trans-homophilic interaction BibTex
2008-02-26 R-HSA-210277 Interaction of PECAM-1 and SHP-1 BibTex
2008-02-26 R-HSA-210290 Interaction of PECAM-1 and SHIP BibTex
2008-02-26 R-HSA-210285 Trans-homophilic interaction of PECAM-1 BibTex
2008-02-26 R-HSA-210294 Interaction of PECAM-1 and SHP-2 BibTex
2008-02-26 R-HSA-210283 Interaction of PECAM-1 and PLC gamma1 BibTex
2008-02-26 R-HSA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src BibTex
2008-02-26 R-HSA-375131 Basigin binds CD98 complex BibTex
2008-02-26 R-HSA-204392 Basigin binds MCT1, MCT3 and MCT4 BibTex
2008-02-26 R-HSA-375133 Basigin binds Mannose-carrying cell recognition molecules BibTex
2008-02-26 R-HSA-204465 Basigin interacts with CD43 BibTex
2008-02-26 R-HSA-204500 CyP60 chaperones Basigin BibTex
2008-02-26 R-HSA-204600 Basigin homodimerises BibTex
2008-02-26 R-HSA-375135 Basigin binds Matrix metalloproteinase-1 BibTex
2008-02-26 R-HSA-204485 Basigin binds CyPA BibTex
2008-02-26 R-HSA-204549 Caveolin-1 binds Basigin BibTex
2008-02-26 R-HSA-373741 SDK2 homophillic interaction BibTex
2008-02-26 R-HSA-373745 SDK1 homophillic interaction BibTex
2008-02-26 R-HSA-210304 Interaction of integrin alphaVbeta3 with PECAM1 BibTex
2008-02-06 R-HSA-210282 Interaction of GPVI and FceRI gamma BibTex
2008-01-24 R-HSA-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB BibTex
2008-01-24 R-HSA-202534 Ubiquitination of NEMO by TRAF6 BibTex
2008-01-24 R-HSA-202500 Activation of IKK complex BibTex
2008-01-24 R-HSA-202510 Activation of TAK1-TAB2 complex BibTex
2008-01-24 R-HSA-202237 Hydrolysis of PIP3 to PI(3,4)P2 BibTex
2008-01-24 R-HSA-202164 Translocation of PDK1 to Plasma membrane BibTex
2008-01-24 R-HSA-202328 Translocation of PKC theta to plasma membrane BibTex
2008-01-24 R-HSA-202307 Change of PKC theta conformation BibTex
2008-01-24 R-HSA-202222 Phosphorylation of PKC theta BibTex
2008-01-24 R-HSA-202394 Translocation of CARMA1 to Plasma membrane BibTex
2008-01-24 R-HSA-202437 Phosphorylation of CARMA1 BibTex
2008-01-24 R-HSA-202443 Oligomerization of CARMA1 BibTex
2008-01-24 R-HSA-202466 Interaction of Bcl10 to CARMA1 BibTex
2008-01-24 R-HSA-202459 Phosphorylation of Bcl10 BibTex
2008-01-24 R-HSA-202489 Oligomerization of Bcl10 BibTex
2008-01-24 R-HSA-202478 Interaction and oligomerization of MALT1 to Bcl10 BibTex
2008-01-24 R-HSA-202472 Translocation of TRAF6 to CBM complex BibTex
2008-01-24 R-HSA-202453 Auto-ubiquitination of TRAF6 BibTex
2008-01-24 R-HSA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 BibTex
2008-01-24 R-HSA-202203 Recruitment of PI3K to plasma membrane BibTex
2008-01-24 R-HSA-213406 Disassociation of PLC-gamma1 from LAT BibTex
2008-01-24 R-HSA-213407 Disassociation of PLC-gamma1 from SLP-76 BibTex
2008-01-24 R-HSA-202331 Recruitment of PLC-gamma1 to SLP-76 BibTex
2008-01-24 R-HSA-202212 Recruitment of PLC-gamma1 to LAT BibTex
2008-01-24 R-HSA-203774 Interaction of Csk with PAG BibTex
2008-01-24 R-HSA-202233 Inactivation of Lck by Csk BibTex
2008-01-24 R-HSA-202214 Dephosphorylation of Lck-pY505 by CD45 BibTex
2008-01-24 R-HSA-202291 Activation of Lck BibTex
2008-01-24 R-HSA-202165 Phosphorylation of ITAM motifs in CD3 complexes BibTex
2008-01-24 R-HSA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs BibTex
2008-01-24 R-HSA-202168 Phosphorylation of ZAP-70 by Lck BibTex
2008-01-24 R-HSA-202174 Activation of ZAP-70 BibTex
2008-01-24 R-HSA-202245 Phosphorylation of TBSMs in LAT BibTex
2008-01-24 R-HSA-202325 Recruitment of Gads to LAT BibTex
2008-01-24 R-HSA-202241 Recruitment of SLP-76 to Gads BibTex
2008-01-24 R-HSA-202216 Phosphorylation of SLP-76 BibTex
2008-01-24 R-HSA-202375 Recruitment of ITK to SLP-76 BibTex
2008-01-24 R-HSA-202248 Phosphorylation of PLC-gamma1 BibTex
2008-01-24 R-HSA-202354 Translocation of PLC-gamma1 to PIP2 BibTex
2008-01-24 R-HSA-202407 PLC-gamma1 hydrolyses PIP2 BibTex
2007-07-08 R-HSA-199161 Fc gamma receptors interact with antigen-bound IgG BibTex
2007-07-08 R-HSA-199154 CD200 binds to CD200R BibTex
2007-07-08 R-HSA-198958 KIR2DL2/3 interacting with HLA-C group 1 (Cw4) BibTex
2007-07-08 R-HSA-199144 Nectin 2 binds CD226 BibTex
2007-07-08 R-HSA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I BibTex
2007-07-08 R-HSA-199014 CD96 binds PVR BibTex
2007-07-08 R-HSA-199079 Epithelial cadherin binds to KLRG1 BibTex
2007-07-08 R-HSA-199587 KIR2DS1 interacting with HLA-C group 2 (Cw4) BibTex
2007-07-08 R-HSA-199518 C3d-complexed antigen binds to complement receptor BibTex
2007-07-08 R-HSA-199583 KIR2DS2 interacting with HLA-C group 1 (Cw3) BibTex
2007-07-08 R-HSA-199576 KIR3DL2 interacting with HLA-A3 BibTex
2007-07-08 R-HSA-199579 KIR2DL4 interacting with HLA-G BibTex
2007-07-08 R-HSA-199131 PVR binds CD226 BibTex
2007-07-08 R-HSA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E BibTex
2007-07-08 R-HSA-199566 KIR3DL1 interacting with HLA Bw4 BibTex
2007-07-08 R-HSA-199112 CRTAM binds to NECL2 BibTex
2007-07-08 R-HSA-199558 KIR2DL1 interacting with HLA-C group 2 (Cw3) BibTex
2007-07-08 R-HSA-199046 Ligands bind L-selectin BibTex
2007-07-08 R-HSA-198983 NKG2D homodimer interacting with ligands BibTex
2007-07-08 R-HSA-199169 MHC Class I interacts with CD160 BibTex
2007-07-08 R-HSA-199043 LILRs interact with MHC Class I BibTex
2007-07-08 R-HSA-199404 CD40L binds CD40 BibTex
2007-07-08 R-HSA-199032 MADCAM1-1 binds Integrin alpha4beta7 BibTex
2007-07-08 R-HSA-198941 VCAM1 binds Integrin alpha4beta1 BibTex
2007-07-08 R-HSA-199050 ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) BibTex
2007-01-10 R-HSA-5654607 Activated FGFR2 phosphorylates PPTN11 BibTex
2007-01-10 R-HSA-5654608 Activated FGFR2:p-FRS bind to PPTN11 BibTex
2007-01-10 R-HSA-5654584 Activated FGFR1:p-FRS bind to PPTN11 BibTex
2007-01-10 R-HSA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 BibTex
2007-01-10 R-HSA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 BibTex
2007-01-10 R-HSA-5654397 Activated FGFR2 phosphorylates FRS2 BibTex
2007-01-10 R-HSA-190408 Autocatalytic phosphorylation of FGFR2b BibTex
2007-01-10 R-HSA-190260 FGFR2b binds to FGF BibTex
2007-01-10 R-HSA-190413 Autocatalytic phosphorylation of FGFR2c BibTex
2007-01-10 R-HSA-190258 FGFR2c binds to FGF BibTex
2007-01-10 R-HSA-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 BibTex
2007-01-10 R-HSA-5654631 Activated FGFR3 phosphorylates PPTN11 BibTex
2007-01-10 R-HSA-5654633 Activated FGFR3:p-FRS bind to PPTN11 BibTex
2007-01-10 R-HSA-5654628 Activated FGFR3 phosphorylates FRS3 BibTex
2007-01-10 R-HSA-190385 Autocatalytic phosphorylation of FGFR3b BibTex
2007-01-10 R-HSA-190263 FGFR3b binds to FGF BibTex
2007-01-10 R-HSA-190388 Autocatalytic phosphorylation of FGFR3c BibTex
2007-01-10 R-HSA-190261 FGFR3c binds to FGF BibTex
2007-01-10 R-HSA-5654408 Activated FGFR3 phosphorylates FRS2 BibTex
2007-01-10 R-HSA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 BibTex
2007-01-10 R-HSA-5654575 Activated FGFR1 phosphorylates FRS2 BibTex
2007-01-10 R-HSA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c BibTex
2007-01-10 R-HSA-190268 FGFR1c binds to Klotho-bound FGF23 BibTex
2007-01-10 R-HSA-190427 Autocatalytic phosphorylation of FGFR1b BibTex
2007-01-10 R-HSA-190245 FGFR1b binds to FGF BibTex
2007-01-10 R-HSA-190429 Autocatalytic phosphorylation of FGFR1c BibTex
2007-01-10 R-HSA-190256 FGFR1c binds to FGF BibTex
2007-01-10 R-HSA-5654605 Activated FGFR2 phosphorylates FRS3 BibTex
2007-01-10 R-HSA-190326 Autocatalytic phosphorylation of FGFR4 BibTex
2007-01-10 R-HSA-190265 FGFR4 binds to FGF BibTex
2007-01-10 R-HSA-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 BibTex
2007-01-10 R-HSA-5654222 Activated FGFR3 phosphorylates PLCG1 BibTex
2007-01-10 R-HSA-5654224 Activated FGFR3 binds PLCG1 BibTex
2007-01-10 R-HSA-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 BibTex
2007-01-10 R-HSA-5654149 Activated FGFR1 phosphorylates PLCG1 BibTex
2007-01-10 R-HSA-5654167 Activated FGFR1 binds PLCG1 BibTex
2007-01-10 R-HSA-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 BibTex
2007-01-10 R-HSA-5654147 Activated FGFR2 phosphorylates PLCG1 BibTex
2007-01-10 R-HSA-5654159 Activated FGFR2 binds PLCG1 BibTex
2007-01-10 R-HSA-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 BibTex
2007-01-10 R-HSA-5654151 Activated FGFR4 phosphorylates PLCG1 BibTex
2007-01-10 R-HSA-5654163 Activated FGFR4 binds PLCG1 BibTex
2007-01-10 R-HSA-5654653 Activated FGFR4 phosphorylates FRS3 BibTex
2007-01-10 R-HSA-5654418 Activated FGFR4 phosphorylates FRS2 BibTex
2007-01-10 R-HSA-5654658 Activated FGFR4:p-FRS bind to PPTN11 BibTex
2007-01-10 R-HSA-5654655 Activated FGFR4 phosphorylates PPTN11 BibTex
2007-01-10 R-HSA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 BibTex
2007-01-10 R-HSA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 BibTex
2007-01-10 R-HSA-5654578 Activated FGFR1 phosphorylates FRS3 BibTex
2006-07-21 R-HSA-183122 Factor D cleaves C3b-bound Factor B BibTex
2006-07-21 R-HSA-183126 Factor B binds to surface-associated C3b BibTex
2006-02-16 R-HSA-183130 C3(H2O):Factor Bb cleaves C3 to C3b and C3a BibTex
2005-08-16 R-HSA-9014342 K63-linked ubiquitination of RIP1 bound to the activated TLR complex BibTex
2005-08-16 R-HSA-9013978 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex BibTex
2005-08-16 R-HSA-9013979 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR3 BibTex
2005-08-16 R-HSA-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) BibTex
2005-08-16 R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex BibTex
2005-08-16 R-HSA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex BibTex
2005-08-16 R-HSA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 BibTex
2005-08-16 R-HSA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex BibTex
2005-08-16 R-HSA-166869 TRAF6 binds MEKK1 BibTex
2005-08-16 R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex BibTex
2005-08-16 R-HSA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 BibTex
2005-08-16 R-HSA-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) BibTex
2005-08-16 R-HSA-169719 Secreted CD14 binds LPS BibTex
2005-08-16 R-HSA-166015 Association of LBP with LPS BibTex
2005-08-16 R-HSA-166038 GPI-bound CD14 binds LPS BibTex
2005-08-16 R-HSA-166041 Transfer of LPS onto TLR4 BibTex
2005-08-16 R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 BibTex
2005-08-16 R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex BibTex
2005-08-16 R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex BibTex
2005-08-16 R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal BibTex
2005-08-16 R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP BibTex
2005-08-16 R-HSA-166286 Multiple IRAK1 autophosphorylation steps BibTex
2005-08-16 R-HSA-166363 TRAF6 binds to hp- IRAK1 BibTex
2005-08-16 R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex BibTex
2005-08-09 R-HSA-165680 Formation of active mTORC1 complex BibTex
2004-09-25 R-HSA-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it BibTex
2004-09-25 R-MMU-351337 Release of 78 kDa glucose-regulated protein BibTex
2004-09-25 R-HSA-351323 Release of 78 kDa glucose-regulated protein BibTex
2004-09-25 R-MMU-350735 Release of Calumenin BibTex
2004-09-25 R-HSA-350745 Release of Calumenin BibTex
2004-09-25 R-HSA-481007 Exocytosis of platelet alpha granule contents BibTex
2004-09-25 R-HSA-481009 Exocytosis of platelet dense granule content BibTex
2004-09-25 R-HSA-482770 Release of platelet secretory granule components BibTex
2004-09-25 R-HSA-481010 Surface deployment of platelet dense granule membrane components BibTex
2004-09-25 R-HSA-482772 Release of platelet cytosolic components BibTex
2004-09-25 R-HSA-481044 Surface deployment of platelet alpha granule membrane components BibTex
2004-09-25 R-MMU-482767 Release of mouse platelet cytosolic components BibTex
2004-09-25 R-HSA-482775 Release of (inferred) platelet cytosolic components BibTex
2004-09-25 R-HSA-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them BibTex
2004-08-04 R-HSA-173725 C9 binds C5b:C6:C7:C8 BibTex
2004-08-04 R-HSA-173705 C5b binds C6 BibTex
2004-08-04 R-HSA-173709 C7 binds C5b:C6 BibTex
2004-08-04 R-HSA-173720 C5b:C6:C7 translocates to the plasma membrane BibTex
2004-08-04 R-HSA-173723 C8 binds C5b:C6:C7 BibTex
2004-08-04 R-HSA-166817 Cleavage of C3 by C3 convertases BibTex
2004-08-04 R-HSA-174551 Formation of alternative pathway C5 convertase BibTex
2004-08-04 R-HSA-173754 Properdin stabilizes C3b:Bb bound to cell surfaces BibTex
2004-08-04 R-HSA-173745 Factor D cleaves C3(H2O)-bound Factor B BibTex
2004-08-04 R-HSA-173740 Factor B binds to C3(H2O) BibTex
2004-08-04 R-HSA-173739 Spontaneous hydrolysis of C3 thioester BibTex
2004-08-04 R-HSA-166795 Formation of Classical C3 convertase (C4b:C2a complex) BibTex
2004-08-04 R-HSA-166792 Conversion of C2 into C2a and C2b BibTex
2004-08-04 R-HSA-166726 Activation of MASPs BibTex
2004-08-04 R-HSA-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa BibTex
2004-08-04 R-HSA-166753 Conversion of C4 into C4a and C4b BibTex
2004-08-04 R-HSA-173631 Activation of C1s BibTex
2004-08-04 R-HSA-173626 Activation of C1r BibTex
2004-08-04 R-HSA-173680 Activation of C5 BibTex
2004-08-04 R-HSA-173636 Formation of classic pathway C5 convertase BibTex
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