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2022-05-02
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R-HSA-2186780
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Degradation of Ub-SMAD7
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BibTex
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2022-05-02
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R-HSA-2187293
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SMAD2/3:SMAD4 complex positively regulates JUNB transcription
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BibTex
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2022-05-02
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R-HSA-2106586
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WWTR1:SMAD stimulates transcription of SERPINE1 while TGIF:SMAD and SMAD7 inhibit it
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BibTex
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2022-05-02
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R-HSA-9733216
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COL1A2 gene expression is stimulated by p-2S-SMAD3:p-2S-SMAD3:SMAD4
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BibTex
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2022-05-02
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R-HSA-9736992
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p-2S-SMAD2,3:SMAD4 binds JUNB gene promoter
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BibTex
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2022-05-02
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R-HSA-2186643
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MEN1 binds SMAD2/3:SMAD4 heterotrimer
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BibTex
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2022-05-02
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R-HSA-9736953
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FURIN translocates to the plasma membrane
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BibTex
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2022-05-02
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R-HSA-170847
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Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4
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BibTex
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2022-05-02
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R-HSA-870538
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TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus
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BibTex
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2022-05-02
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R-HSA-173481
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SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling
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BibTex
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2022-05-02
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R-NUL-2186736
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Rnf111 binds SKI/SKIL in complex with SMAD2/3:SMAD4 upon TGF-beta stimulation
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BibTex
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2022-05-02
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R-HSA-2186741
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SMAD2/3 activation induces binding of RNF111/SMURF2 to SKI/SKIL
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BibTex
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2022-05-02
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R-HSA-2176475
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Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9
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BibTex
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2022-05-02
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R-HSA-2179274
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SMURF2 binds SMAD3 phosphorylated in the linker region
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BibTex
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2022-05-02
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R-HSA-2179276
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SMURF2 monoubiquitinates SMAD3
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BibTex
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2022-05-02
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R-HSA-9730967
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STAT1 stimulates SMAD7 gene transcription
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BibTex
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2022-05-02
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R-HSA-5252001
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ATP1B4 binds SNW1
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BibTex
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2022-05-02
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R-HSA-2031355
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WWTR1 binds SMAD2/3:SMAD4 heterotrimer
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BibTex
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2022-05-02
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R-HSA-2106579
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WWTR1:SMAD translocates to the nucleus
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BibTex
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2022-05-02
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R-HSA-9736970
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WWTR1:p-2S-SMAD2,3:SMAD4 binds SMAD7 gene promoter
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BibTex
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2022-05-02
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R-HSA-2106591
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WWTR1:SMAD stimulates transcription of SMAD7
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BibTex
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2022-05-02
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R-HSA-2186771
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RNF111 binds SMAD7
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BibTex
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2022-05-02
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R-NUL-2186775
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Rnf111 ubiquitinates Smad7
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BibTex
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2022-05-02
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R-HSA-2186785
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RNF111 ubiquitinates SMAD7
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BibTex
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2022-05-02
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R-NUL-2186755
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Ubiquitination of SKI/SKIL by Rnf111
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BibTex
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2022-05-02
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R-HSA-2186747
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Ubiquitination of SKI/SKIL by RNF111/SMURF2
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BibTex
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2022-05-02
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R-HSA-870449
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TRIM33 monoubiquitinates SMAD4
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BibTex
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2022-05-02
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R-HSA-870477
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Ubiquitinated SMAD4 translocates from the nucleus to the cytosol
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BibTex
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2022-05-02
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R-HSA-870479
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USP9X (FAM) binds to ubiquitinated SMAD4
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BibTex
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2022-05-02
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R-HSA-870437
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USP9X (FAM) deubiquitinates SMAD4
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BibTex
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2022-05-02
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R-HSA-173488
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The SMAD2/3:SMAD4 complex transfers to the nucleus
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BibTex
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2022-05-02
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R-HSA-2127257
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SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2
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BibTex
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2022-05-02
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R-HSA-9736984
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p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 binds MYC gene promoter
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BibTex
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2022-05-02
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R-HSA-1484099
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MYC trancscription is negatively regulated by SMAD2/3:SMAD4:RBL1:E2F4/5:DP1/2 complex
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BibTex
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2022-05-02
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R-HSA-2187309
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SMAD2/3:SMAD4 heterotrimer binds SP1
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BibTex
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2022-05-02
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R-HSA-9736979
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p-2S-SMAD2,3:SMAD4:SP1 binds CDKN2B gene promoter
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2022-05-02
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R-HSA-2187303
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SMAD2/3:SMAD4:SP1 complex stimulates transcription of CDKN2B
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BibTex
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2022-05-02
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R-HSA-2176491
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NEDD4L binds phosphorylated linker region of SMAD2/3
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BibTex
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2022-05-02
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R-HSA-2176502
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NEDD4L ubiquitinates SMAD2/3
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BibTex
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2022-05-02
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R-HSA-2186607
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TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer
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BibTex
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2022-05-02
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R-HSA-9736966
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SMAD7 binds SERPINE1 gene promoter
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BibTex
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2022-05-02
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R-HSA-2176503
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Degradation of SMAD2/3:SMAD4 complex
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BibTex
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2022-05-02
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R-HSA-2187330
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PARP1 binds SMAD2/3:SMAD4 heterotrimer
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BibTex
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2022-05-02
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R-HSA-2187325
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PARP1 ADP-ribosylates SMAD3 and SMAD4
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BibTex
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2022-05-02
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R-HSA-2187388
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PPM1A protein phosphatase binds phosphorylated SMAD2/3
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BibTex
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2022-05-02
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R-HSA-209055
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PPM1A dephosphorylates nuclear SMAD2/3
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BibTex
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2022-05-02
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R-HSA-2187395
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Dephosphorylated SMAD2/3 translocates to the cytosol
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BibTex
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2022-05-02
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R-HSA-173545
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Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling
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BibTex
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2022-05-02
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R-HSA-2186767
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Degradation of ubiquitinated SKI/SKIL
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BibTex
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2022-05-02
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R-HSA-9731111
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MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3
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BibTex
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2022-05-02
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R-HSA-9733207
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p-2S-SMAD3:p-2S-SMAD3:SMAD4 forms a complex with SP1 and EP300 at the COL1A2 gene promoter
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BibTex
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2022-05-02
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R-HSA-9733203
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FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4
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BibTex
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2022-05-02
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R-HSA-9736959
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WWTR1:p-2S-SMAD2,3:SMAD4 binds SERPINE1 gene promoter
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BibTex
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2022-05-02
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R-HSA-9733247
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YBX1 binds COL1A2 gene promoter
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BibTex
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