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Thawfeek Varusai

 ORCID
https://orcid.org/0000-0002-7864-5971
Authored Reactions (186)
Date Identifier Reaction Reference
2020-05-26 R-HSA-9698265 Enhanced autophagosome formation BibTex
2020-05-26 R-HSA-9694580 nsp8 binds MAP1LC3B BibTex
2020-05-19 R-HSA-9687435 Enhanced autophagosome formation BibTex
2020-05-06 R-HSA-9687109 8b binds MAP1LC3B BibTex
2020-05-06 R-HSA-9687121 nsp8 binds MAP1LC3B BibTex
2020-02-24 R-MMU-8964229 G alpha (i):GTP binds Src BibTex
2020-01-06 R-HSA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 BibTex
2020-01-06 R-HSA-9674131 USP30 binds ATM dimer:Ub-p-PEX5 BibTex
2019-11-08 R-MMU-9631076 Hspa8:substrate binds late endosomal phospholipids BibTex
2019-11-08 R-MMU-9631080 Substrate translocates into late endosomal lumen BibTex
2019-11-08 R-RNO-9613356 Plins bind Hspa8 BibTex
2019-11-08 R-MMU-9613507 Plins:Hspa8 binds Prkaa2 BibTex
2019-11-08 R-MMU-9613545 Prkaa2 phosphorylates Plins BibTex
2019-11-08 R-MMU-9613670 p-Plins translocate from lipid droplet surface to cytosol BibTex
2019-11-08 R-RNO-9626032 Eef1a1 dissociates from p-Gfap BibTex
2019-11-08 R-RNO-9626037 p-Gfap binds Eef1a1 BibTex
2019-11-08 R-RNO-9626064 Eef1a1:GTP translocates from lysosomal membrane to cytosol BibTex
2019-11-08 R-RNO-9626036 Eef1a1 binds GTP BibTex
2019-11-08 R-RNO-9626254 Hspa8:Lamp2 multimers depolymerizes to monomers BibTex
2019-11-08 R-RNO-9626239 Hspa8 binds Lamp2 multimers BibTex
2019-11-08 R-RNO-9626250 p-Gfap:Gfap dissociates from Lamp2 multimer BibTex
2019-11-08 R-RNO-9626030 p-Gfap binds Gfap in Lamp2 multimer BibTex
2019-11-08 R-RNO-9626028 Hspa8:Substrate dissociates from Lamp2 multimer BibTex
2019-11-08 R-RNO-9625160 Hspa8 transports unfolded substrate to lysosomal lumen for degradation BibTex
2019-11-08 R-RNO-9625173 Unfolded substrate in Lamp2 multimeric complex binds Hspa8 BibTex
2019-11-08 R-RNO-9625183 Gfap binds Lamp2 multimer BibTex
2019-11-08 R-RNO-9624154 Substrate:Lamp2a:Hsp90 polymerizes BibTex
2019-11-08 R-RNO-9622851 Substrate:Lamp2a binds Hsp90 BibTex
2019-11-08 R-RNO-9622832 Hspa8 dissociates from Lamp2a-bound substrate BibTex
2019-11-08 R-RNO-9620205 Hspa8:Rnase1 binds Lamp2a BibTex
2019-11-08 R-RNO-9626275 Hsp90 dissociates from Lamp2 BibTex
2019-11-08 R-RNO-9626236 Hspa8 dissociates from Lamp2 BibTex
2019-11-08 R-RNO-9615712 Hspa8 binds Rnase1 BibTex
2019-11-04 R-MMU-9666410 Nbr1 translocates from cytosol to perixosomal membrane BibTex
2019-10-29 R-HSA-9664867 NBR1 binds MAP1LC3B BibTex
2019-10-29 R-HSA-9664855 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 BibTex
2019-10-29 R-HSA-9664880 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 BibTex
2019-10-29 R-HSA-9664871 NBR1 translocates from cytosol to perixosomal membrane BibTex
2019-10-29 R-HSA-9664892 SQSTM1 binds ATM dimer:Ub-p-PEX5 BibTex
2019-10-29 R-HSA-9664881 NBR1 binds ATM:Ub-p-PEX5:SQSTM1 BibTex
2019-10-29 R-HSA-9664879 ATM:PEX5 binds ATM BibTex
2019-10-29 R-HSA-9664862 ATM dimer:PEX5 phosphorylates PEX5 BibTex
2019-10-29 R-HSA-9664888 ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 BibTex
2019-10-29 R-HSA-9664850 ATM binds PEX5 BibTex
2019-10-29 R-HSA-9664883 ATM:PEX5 translocates from cytosol to peroxisomal membrane BibTex
2019-06-14 R-HSA-9640480 E2 enzyme UBE2N:UBE2V1 binds ubiquitin BibTex
2019-05-23 R-HSA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome BibTex
2019-05-23 R-HSA-9646685 Aggresome dissociates from dynein and microtubule BibTex
2019-05-23 R-MMU-9646393 Hdac6 binds microtubule BibTex
2019-05-23 R-HSA-9646390 Misfolded proteins:HDAC6:Dynein motor binds microtubule BibTex
2019-05-23 R-NUL-9646387 Dynein motors transport misfolded proteins BibTex
2019-05-23 R-HSA-9646383 Dynein motors transport misfolded proteins BibTex
2019-05-07 R-HSA-9646347 PolyUb-misfolded proteins bind VCP:HDAC6:HSP90:HSF1 BibTex
2019-05-07 R-MMU-9646359 PolyUb-Misfolded Proteins:Hdac6 dissociate from complex BibTex
2019-05-07 R-HSA-9646354 PolyUb-Misfolded Proteins:HDAC6 dissociate from complex BibTex
2019-05-07 R-HSA-9646348 PolyUb-Misfolded Proteins:HDAC6 bind dynein motor BibTex
2019-04-04 R-HSA-9641111 Parkin transfers Ub to misfolded proteins BibTex
2019-04-04 R-HSA-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins BibTex
2019-04-04 R-HSA-9641109 PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 BibTex
2019-04-02 R-HSA-9641089 Parkin binds Ub:UBE2N:UBE2V1 BibTex
2019-04-02 R-HSA-9641096 Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub BibTex
2019-03-21 R-SCE-9640470 E2 enzyme MMS2:UBC13 binds ubiquitin BibTex
2019-03-19 R-MMU-9640117 Misfolded proteins translocate from cilium to cytosol BibTex
2019-03-19 R-HSA-9640114 Misfolded proteins translocate from cilium to cytosol BibTex
2019-03-18 R-HSA-9639698 ROS positively regulates misfolding of cilia proteins BibTex
2019-03-18 R-MMU-9639715 ROS positively regulates misfolding of cilia proteins BibTex
2019-02-23 R-HSA-9645134 p-STAT5 dissociates from activator:STAT5 complex BibTex
2019-02-23 R-HSA-9645126 Activators bind STAT5 BibTex
2019-02-23 R-MMU-9645128 Activators bind Stat5 BibTex
2019-02-23 R-MMU-9645136 Activator phosphorylates Stat5 BibTex
2019-02-23 R-HSA-9645137 Activator phosphorylates STAT5 BibTex
2019-02-23 R-MMU-9606621 Gab2 in Active Flt3:Grb2:Gab2 is phosphorylated BibTex
2019-02-21 R-HSA-9631068 HSPA8:substrate binds late endosomal phospholipids BibTex
2019-02-21 R-HSA-9631065 Substrate translocates into late endosomal lumen BibTex
2019-02-21 R-HSA-9613352 PLINs bind HSPA8 BibTex
2019-02-21 R-HSA-9613513 PLINs:HSPA8 binds PRKAA2 BibTex
2019-02-21 R-HSA-9613530 PRKAA2 phosphorylates PLINs BibTex
2019-02-21 R-HSA-9613565 PRKAA2 dissociate from p-PLINs:HSPA8 BibTex
2019-02-21 R-HSA-9613666 p-PLINs translocate from lipid droplet surface to cytosol BibTex
2019-02-21 R-HSA-9615721 HSPA8 binds substrate BibTex
2019-02-21 R-HSA-9620197 HSPA8:Substrate binds LAMP2a BibTex
2019-02-21 R-HSA-9622840 HSPA8 dissociates from LAMP2A-bound substrate BibTex
2019-02-21 R-HSA-9626235 HSPA8 dissociates from LAMP2a BibTex
2019-02-21 R-HSA-9626276 HSP90 dissociates from LAMP2a BibTex
2019-02-21 R-HSA-9622831 Substrate:LAMP2a binds HSP90 BibTex
2019-02-21 R-HSA-9624158 Substrate:LAMP2a:HSP90 polymerizes BibTex
2019-02-21 R-HSA-9625197 GFAP binds LAMP2a multimer BibTex
2019-02-21 R-HSA-9625196 Unfolded substrate in LAMP2a multimeric complex binds HSPA8 BibTex
2019-02-21 R-HSA-9625188 HSPA8 transports unfolded substrate to lysosomal lumen for degradation BibTex
2019-02-21 R-HSA-9626060 HSPA8:Substrate dissociates from LAMP2a multimer BibTex
2019-02-21 R-HSA-9626039 pGFAP binds GFAP in LAMP2a multimer BibTex
2019-02-21 R-HSA-9626242 p-GFAP:GFAP dissociates from LAMP2a multimer BibTex
2019-02-21 R-HSA-9626253 HSPA8 binds LAMP2a multimers BibTex
2019-02-21 R-HSA-9626256 HSPA8:LAMP2a multimers depolymerizes to monomers BibTex
2019-02-21 R-HSA-9626038 EEF1A1 binds GTP BibTex
2019-02-21 R-HSA-9626067 EEF1A1:GTP translocates from lysosomal membrane to cytosol BibTex
2019-02-21 R-HSA-9626046 p-GFAP binds EEF1A1 BibTex
2019-02-21 R-HSA-9626034 EEF1A1 dissociates from p-GFAP BibTex
2019-01-14 R-MMU-9605258 Active Flt3 binds Fyn BibTex
2019-01-14 R-HSA-9605259 Active FLT3 binds FYN BibTex
2019-01-14 R-MMU-9609272 Active Flt3 binds Hck BibTex
2019-01-14 R-HSA-9609274 Active FLT3 binds HCK BibTex
2019-01-14 R-MMU-9604980 Active Flt3 binds Ptpn11 BibTex
2019-01-14 R-HSA-9604969 Active FLT3 binds PTPN11 BibTex
2019-01-14 R-MMU-9606789 Active Flt3:Grb2:p-Y-Gab2 binds Ptpn11 BibTex
2019-01-14 R-HSA-9606784 Active FLT3:GRB2:p-Y-GAB2 binds PTPN11 BibTex
2019-01-14 R-HSA-9606624 Active FLT3:GRB2 binds GAB2 BibTex
2019-01-14 R-HSA-9606622 GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated BibTex
2019-01-14 R-MMU-9606623 Active Flt3:Grb2 binds Gab2 BibTex
2019-01-14 R-MMU-9607226 Active Flt3:Grb2:p-Y-Gab2 binds Pik3r1 BibTex
2019-01-14 R-HSA-9607224 Active FLT3:GRB2:p-Y-GAB2 binds PIK3R1 BibTex
2019-01-14 R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates BibTex
2019-01-14 R-MMU-9604768 Active Flt3 dimer binds Grb2 BibTex
2019-01-14 R-HSA-9604738 Active FLT3 dimer binds GRB2 BibTex
2019-01-14 R-HSA-9607301 Active FLT3:GRB2 binds SOS1 BibTex
2019-01-14 R-HSA-9607304 SOS1-mediated nucleotide exchange of RAS donwstream of FLT3 BibTex
2017-09-27 R-HSA-9008894 PTPNs gene transcription and translation BibTex
2017-09-27 R-HSA-9008684 TBK1 phosphorylation BibTex
2017-09-27 R-HSA-9009072 STAT3 phosphorylation BibTex
2017-09-27 R-HSA-9008696 IL37(?-218) translocates from the cytosol to the nucleus BibTex
2017-09-27 R-HSA-9008587 IL37, IL37(?-218) binds IL18BP BibTex
2017-09-27 R-HSA-9008577 IL37:IL18R1 binds SIGIRR BibTex
2017-09-27 R-HSA-9008692 IL37(?-218) binds SMAD3 BibTex
2017-09-27 R-HSA-9008694 IL37, IL37(?-218) translocates from cytosol to extracellular region BibTex
2017-09-27 R-HSA-9008928 IL37(?-218):p-S423,S425-SMAD3 translocates to the nucleus BibTex
2017-09-27 R-HSA-9009910 IL37(?-218) binds p-S423,S425-SMAD3 BibTex
2017-07-27 R-HSA-8964287 G alpha (s):GTP:SRC dissociates BibTex
2017-07-27 R-HSA-8964278 G protein alpha (s):GTP binds SRC BibTex
2017-07-27 R-HSA-8964252 G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC BibTex
2017-07-27 R-HSA-8964340 Gq-BTK complex dissociates to Active BTK and Gq BibTex
2017-07-27 R-HSA-8964284 BTK in active Gq-BTK complex is activated BibTex
2017-07-27 R-HSA-8964280 Active Gq binds BTK BibTex
2017-07-27 R-HSA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) BibTex
2017-07-27 R-HSA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) BibTex
2017-07-27 R-HSA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated BibTex
2017-07-27 R-HSA-8981892 Active G alpha (z) binds RGS proteins BibTex
2017-07-27 R-HSA-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex BibTex
2017-07-27 R-HSA-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex BibTex
2017-07-27 R-HSA-8964619 PAK1 binds ARHGEF6 BibTex
2017-07-27 R-HSA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated BibTex
2017-07-27 R-HSA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated BibTex
2017-07-27 R-HSA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex BibTex
2017-07-27 R-HSA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex BibTex
2017-07-27 R-HSA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated BibTex
2017-07-27 R-HSA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane BibTex
2017-07-27 R-HSA-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC BibTex
2017-07-27 R-HSA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC BibTex
2017-07-27 R-HSA-8964311 G alpha (i):GTP binds SRC BibTex
2017-07-27 R-HSA-8982019 Active G alpha (i)?i1/i2/i3 binds RGS proteins BibTex
2017-07-27 R-HSA-8982020 G alpha (i)?i1/i2/i3 in G (i):RGS complex is inactivated BibTex
2017-07-27 R-HSA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)?i1/i2/i3 BibTex
2017-07-27 R-HSA-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) BibTex
2017-07-27 R-HSA-8964246 BTK in G alpha (12)-BTK complex is activated BibTex
2017-07-27 R-HSA-8964274 G alpha (12) binds BTK BibTex
2017-07-27 R-HSA-8982025 G alpha (q) in G (q):RGS complex is inactivated BibTex
2017-07-27 R-HSA-8982017 Active G alpha (q) binds RGS proteins BibTex
2017-07-21 R-HSA-9008052 IL1F10(?-152) binds IL1RAPL1 BibTex
2017-07-21 R-HSA-9007901 IL1F10 binds IL1RL2 BibTex
2017-07-21 R-HSA-9007882 IL1F10 is cleaved BibTex
2017-07-21 R-HSA-9008054 IL1F10 binds IL1RAPL1 BibTex
2017-07-21 R-HSA-9008043 MAPK8 phosphorylation BibTex
2017-06-20 R-HSA-9009558 IL34 dimer binds SDC1 BibTex
2017-06-20 R-HSA-9009554 IL34 dimer:SDC1 binds CSF1R BibTex
2017-06-19 R-HSA-9009488 IL34 binds CSF1 BibTex
2017-06-19 R-HSA-9009485 IL34:CSF1 binds CSF1R BibTex
2017-02-16 R-MMU-9645133 p-Stat5 dissociates from activator:Stat5 complex BibTex
2017-02-16 R-MMU-9646345 Ubiquitin binds Vcp:Hdac6:Hsp90:Hsf1 BibTex
2016-12-15 R-HSA-8983845 p-STAT1 dissociates from IL6ST:IL6ST BibTex
2016-12-15 R-HSA-8984023 p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor BibTex
2016-12-15 R-HSA-8983518 IL35 binds IL6ST:IL6ST receptor BibTex
2016-12-15 R-HSA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated BibTex
2016-12-15 R-HSA-8983841 STAT1 associates with IL6ST:IL6ST BibTex
2016-12-15 R-HSA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 BibTex
2016-12-15 R-HSA-8983878 p-STAT4 dissociates from IL12RB2:IL12RB2 receptor BibTex
2016-12-15 R-HSA-8984964 IL12A gene transcription and translation BibTex
2016-12-15 R-HSA-8983996 STAT1 and STAT4 associate with IL12RB2:IL6ST receptor BibTex
2016-12-15 R-HSA-8983983 p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor BibTex
2016-12-15 R-HSA-8984963 EBI3 gene transcription and translation BibTex
2016-12-15 R-HSA-8983519 IL35 binds IL12RB2:IL12RB2 receptor BibTex
2016-12-15 R-HSA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated BibTex
2016-12-15 R-HSA-8983876 STAT4 binds IL12RB2:IL12RB2 BibTex
2016-12-15 R-HSA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 BibTex
2016-12-15 R-HSA-8984021 STAT1,STAT3 associate with IL27RA:IL12RB2 receptor BibTex
2016-12-15 R-HSA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 BibTex
2016-12-15 R-HSA-8984001 IL35 binds IL27RA:IL12RB2 receptor BibTex
2016-12-15 R-HSA-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated BibTex
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