Carman K M Ip

 ORCID
https://orcid.org/0000-0002-6672-5982
Reviewed Pathways (11/11)
Date Identifier Pathway Reference
2020-02-06 R-HSA-9671555 Signaling by PDGFR in disease BibTex
2020-02-06 R-HSA-9674428 PDGFR mutants bind TKIs BibTex
2020-02-06 R-HSA-9674415 Drug resistance of PDGFR mutants BibTex
2020-02-06 R-HSA-9674396 Imatinib-resistant PDGFR mutants BibTex
2020-02-06 R-HSA-9674404 Sorafenib-resistant PDGFR mutants BibTex
2020-02-06 R-HSA-9674401 Sunitinib-resistant PDGFR mutants BibTex
2020-02-06 R-HSA-9674403 Regorafenib-resistant PDGFR mutants BibTex
2020-02-06 R-HSA-9673768 Signaling by membrane-tethered fusions of PDGFRA or PDGFRB BibTex
2020-02-06 R-HSA-9673770 Signaling by PDGFRA extracellular domain mutants BibTex
2020-02-06 R-HSA-9673766 Signaling by cytosolic PDGFRA and PDGFRB fusion proteins BibTex
2020-02-06 R-HSA-9673767 Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants BibTex
Reviewed Reactions (15/27)
Date Identifier Reaction Reference
2020-02-06 R-HSA-9674430 PDGFR mutants bind type II TKIs BibTex
2020-02-06 R-HSA-9674427 PDGFR mutants bind type I TKIs BibTex
2020-02-06 R-HSA-9674397 Imatinib-resistant PDGFR mutants don't bind imatinib BibTex
2020-02-06 R-HSA-9674414 Sorafenib-resistant PDGFR mutants don't bind sorefenib BibTex
2020-02-06 R-HSA-9674398 D842V PDGFRA doesn't bind sunitinib BibTex
2020-02-06 R-HSA-9674408 Regorafenib-resistant PDGFR mutants don't bind regorafenib BibTex
2020-02-06 R-HSA-9673761 Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB BibTex
2020-02-06 R-HSA-9673760 Ligand-independent dimerization of membrane-tethered fusions of PDGFRA or PDGFRB BibTex
2020-02-06 R-HSA-9672159 STAT binds to p-11Y PDGFRA extracellular domain dimers BibTex
2020-02-06 R-HSA-9672162 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers BibTex
2020-02-06 R-HSA-9672178 PI3-kinase binds to PDGFRA extracellular domain dimers BibTex
2020-02-06 R-HSA-9672163 SOS-mediated nucleotide exchange on RAS downstream of PDGFRA extracellular domain dimers BibTex
2020-02-06 R-HSA-9672158 GRB2:SOS1 complex binds to PDGFRA extracellular domain dimers BibTex
2020-02-06 R-HSA-9672173 Autophosphorylation of PDGFRA extracellular domain dimers BibTex
2020-02-06 R-HSA-9672174 Ligand-independent dimerization of PDGFRA extracellular domain mutants BibTex
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