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Lauren Thorpe

 ORCID
https://orcid.org/0000-0002-5302-9136
Affiliation
Dana-Farber Cancer Institute, Harvard Medical School
Reviewed Reactions (34)
Date Identifier Reaction Reference
2012-08-13 R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity BibTex
2012-08-13 R-HSA-2394007 PI3K gain of function mutants phosphorylate PIP2 to PIP3 BibTex
2012-08-13 R-HSA-2399992 AKT1 E17K mutant phosphorylates forkhead box transcription factors BibTex
2012-08-13 R-HSA-2399999 AKT1 E17K mutant phosphorylates RSK BibTex
2012-08-13 R-HSA-2399966 AKT1 E17K mutant phosphorylates GSK3 BibTex
2012-08-13 R-HSA-2399996 AKT1 E17K mutant phosphorylates CREB1 BibTex
2012-08-13 R-HSA-2399985 AKT1 E17K mutant phosphorylates caspase-9 BibTex
2012-08-13 R-HSA-2399988 AKT1 E17K mutant phosphorylates NR4A1 (NUR77) BibTex
2012-08-13 R-HSA-2399997 AKT1 E17K mutant translocates to the nucleus BibTex
2012-08-13 R-HSA-2400010 AKT inhibitors block AKT membrane recruitment BibTex
2012-08-13 R-HSA-2399977 AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40) BibTex
2012-08-13 R-HSA-2399982 AKT1 E17K mutant phosphorylates TSC2, inhibiting it BibTex
2012-08-13 R-HSA-2399981 AKT1 E17K mutant phosphorylates MDM2 BibTex
2012-08-13 R-HSA-2400001 AKT1 E17K mutant phosphorylates CHUK (IKKalpha) BibTex
2012-08-13 R-HSA-2399969 AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1 BibTex
2012-08-13 R-HSA-2399941 AKT1 E17K mutant phosphorylates BAD BibTex
2012-08-13 R-HSA-2243942 PDPK1 phosphorylates AKT1 E17K mutant BibTex
2012-08-13 R-HSA-2243937 PIP2-bound p-S473-AKT1 mutant binds PIP2-bound PDPK1 BibTex
2012-08-13 R-HSA-2243938 AKT1 E17K mutant is phosphorylated by TORC2 complex BibTex
2012-08-13 R-HSA-2219536 AKT1 E17K mutant binds PIP2 BibTex
2012-08-13 R-HSA-2317387 PTEN cancer mutants do not dephosphorylate PIP3 BibTex
2007-11-08 R-HSA-199425 PHLPP dephosphorylates S473 in AKT BibTex
2007-11-08 R-HSA-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation BibTex
2012-08-13 R-HSA-2219524 PDPK1 binds PIP2 BibTex
2007-11-08 R-HSA-198270 PDPK1 phosphorylates AKT at T308 BibTex
2012-08-13 R-HSA-2317314 AKT binds PDPK1 BibTex
2007-11-08 R-HSA-198640 TORC2 (mTOR) phosphorylates AKT at S473 BibTex
2007-11-08 R-HSA-2317332 PIP3 recruits AKT to the membrane BibTex
2007-11-08 R-HSA-2316429 PIP3 recruits PDPK1 to the membrane BibTex
2007-11-08 R-HSA-199456 PTEN dephosphorylates PIP3 BibTex
2012-08-13 R-HSA-8944497 PTEN mRNA translation is negatively regulated by microRNAs BibTex
2012-08-13 R-HSA-2321904 PTEN mRNA translation negatively regulated by microRNAs BibTex
2012-08-13 R-HSA-2318752 miR-26A microRNAs bind PTEN mRNA BibTex
2012-08-13 R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 BibTex
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