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Rama Krishna Kancha

 ORCID
https://orcid.org/0000-0001-8146-1551
Affiliation
Osmania University
Reviewed Reactions (63)
Date Identifier Reaction Reference
2019-11-03 R-HSA-9665708 ERBB2 TMD/JMD mutants do not bind pertuzumab BibTex
2019-11-03 R-HSA-9665412 ERBB2 ECD mutants bind TKIs BibTex
2019-11-03 R-HSA-9665408 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2 BibTex
2019-11-03 R-HSA-9665409 GRB2:SOS1 binds to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR BibTex
2019-11-03 R-HSA-9665411 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1 BibTex
2019-11-03 R-HSA-9665410 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind PLCG1 BibTex
2019-11-03 R-HSA-9665404 RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1 BibTex
2019-11-03 R-HSA-9665413 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR recruit GRB2:SOS1 through SHC1 BibTex
2019-11-03 R-HSA-9665405 ERBB2 ECD mutants bind trastuzumab BibTex
2019-11-03 R-HSA-9665406 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 BibTex
2019-11-03 R-HSA-9665416 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind SHC1 BibTex
2019-11-03 R-HSA-9665407 PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 BibTex
2019-11-03 R-HSA-9665415 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR, in complex with GRB2:GAB1, bind PI3K BibTex
2019-11-03 R-HSA-9665417 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind GRB2:GAB1 BibTex
2019-11-03 R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate BibTex
2019-11-03 R-HSA-9665388 ERBB2 ECD mutants heterodimerize with EGFR BibTex
2019-11-03 R-HSA-9665704 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1 BibTex
2019-11-03 R-HSA-9665706 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1 BibTex
2019-11-03 R-HSA-9665707 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR BibTex
2019-11-03 R-HSA-9665700 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants BibTex
2019-11-03 R-HSA-9665702 ERBB2 TMD/JMD mutants bind TKIs BibTex
2019-11-03 R-HSA-9665703 ERBB2 TMD/JMD mutants bind pertuzumab BibTex
2019-11-03 R-HSA-9665696 ERBB2 TMD/JMD mutants bind trastuzumab BibTex
2019-11-03 R-HSA-9665698 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind GRB2:SOS1 BibTex
2019-11-03 R-HSA-9665699 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants recruit GRB2:SOS1 through SHC1 BibTex
2019-11-03 R-HSA-9665705 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1 BibTex
2019-11-03 R-HSA-9665701 Phosphorylated ERBB2 TMD/JMD heterodimers bind SHC1 BibTex
2019-11-03 R-HSA-9665709 ERBB2 TMD/JMD heterodimers trans-autophosphorylate BibTex
2019-11-03 R-HSA-9665697 ERBB2 TMD/JMD mutants hetrodimerize BibTex
2019-11-03 R-HSA-9665726 ERBB2 binds pertuzumab BibTex
2019-09-16 R-HSA-9634418 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1 BibTex
2019-09-16 R-HSA-9634402 Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 homodimer BibTex
2019-09-16 R-HSA-9634390 ERBB2 homodimer phosphorylates SHC1 BibTex
2019-09-16 R-HSA-9634391 SHC1 binds phosphorylated ERBB2 homodimer BibTex
2019-09-16 R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer BibTex
2019-09-16 R-HSA-1227964 ERBB2 homodimerization BibTex
2019-09-16 R-HSA-9665304 ERBB2 T862A does not bind sapitinib BibTex
2019-09-16 R-HSA-9665315 ERBB2 T733I does not bind tesevatinib BibTex
2019-09-16 R-HSA-9665286 Resistant ERBB2 KD mutants do not bind neratinib BibTex
2019-09-16 R-HSA-9665280 ERBB2 KD mutants do not bind osimertinib BibTex
2019-09-16 R-HSA-9665311 ERBB2 T798M does not bind afatinib BibTex
2019-09-16 R-HSA-9665232 Resistant ERBB2 KD mutants do not bind trastuzumab BibTex
2019-09-16 R-HSA-9665278 Resistant ERBB2 KD mutants do not bind AEE788 BibTex
2019-09-16 R-HSA-9665284 Resistant ERBB2 KD mutants do not bind lapatinib BibTex
2019-09-16 R-HSA-9664940 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 BibTex
2019-09-16 R-HSA-9665032 Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1 BibTex
2019-09-16 R-HSA-9665034 Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind PLCG1 BibTex
2019-09-16 R-HSA-9664933 Phosphorylated heterodimers of ERBB2 KD mutants and EGFR, in complex with GRB2:GAB1, bind PI3K BibTex
2019-09-16 R-HSA-9665121 ERBB2 KD mutants bind TKIs BibTex
2019-09-16 R-HSA-9664991 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants BibTex
2019-09-16 R-HSA-9664918 Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind GRB2:GAB1 BibTex
2019-09-16 R-HSA-9664664 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 BibTex
2019-09-16 R-HSA-9664646 Phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 bind PI3K BibTex
2019-09-16 R-HSA-9664983 Phosphorylated heterodimers of ERBB2 KD mutants recruit GRB2:SOS1 through SHC1 BibTex
2019-09-16 R-HSA-9664976 Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 BibTex
2019-09-16 R-HSA-9664950 Phosphorylated heterodimers of ERBB2 KD mutants bind SHC1 BibTex
2019-09-16 R-HSA-9649393 ERBB2 KD mutants bind trastuzumab BibTex
2019-09-16 R-HSA-9665009 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR BibTex
2019-09-16 R-HSA-9665000 Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind GRB2:SOS1 BibTex
2019-09-16 R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate BibTex
2019-09-16 R-HSA-9664567 ERBB2 KD mutants heterodimerize BibTex
2019-09-16 R-HSA-9652264 ERBB2 binds TKIs BibTex
2019-09-16 R-HSA-9652277 ERBB2 binds trastuzumab BibTex
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