David J Gregory

 ORCID
https://orcid.org/0000-0001-6534-7150
Reviewed Pathways (14/14)
Date Identifier Pathway Reference
2020-02-04 R-HSA-9658195 Leishmania infection BibTex
2020-02-04 R-HSA-9664424 Cell recruitment (pro-inflammatory response) BibTex
2020-02-04 R-HSA-9660826 Purinergic signaling in leishmaniasis infection BibTex
2020-02-04 R-HSA-9664420 Killing mechanisms BibTex
2020-02-04 R-HSA-9673324 WNT5:FZD7-mediated leishmania damping BibTex
2020-02-04 R-HSA-9664323 FCGR3A-mediated IL10 synthesis BibTex
2020-02-04 R-HSA-9662834 CD163 mediating an anti-inflammatory response BibTex
2020-02-04 R-HSA-9664535 LTC4-CYSLTR mediated IL4 production BibTex
2020-02-04 R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production BibTex
2020-02-04 R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection BibTex
2020-02-04 R-HSA-9664433 Leishmania parasite growth and survival BibTex
2020-02-04 R-HSA-9664422 FCGR3A-mediated phagocytosis BibTex
2020-02-04 R-HSA-9664417 Leishmania phagocytosis BibTex
2020-02-04 R-HSA-9664407 Parasite infection BibTex
Reviewed Reactions (50/50)
Date Identifier Reaction Reference
2020-02-04 R-HSA-9665515 P2RX4,7 binds itself to form trimeric non-selective cation channels BibTex
2020-02-04 R-HSA-9660822 ATP binds P2RX4,7 BibTex
2020-02-04 R-HSA-9673789 Activated JNK phosphorylates c-JUN BibTex
2020-02-04 R-HSA-9673322 p-T,Y-MAPK8 translocates from the cytosol to the nucleoplasm BibTex
2020-02-04 R-HSA-9673284 GTP-bound RAC1 contributes to MAPK8 activation BibTex
2020-02-04 R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen BibTex
2020-02-04 R-HSA-9673794 ppDVL:RAC1:GTP binds NOX1 complex BibTex
2020-02-04 R-HSA-9673288 ppDVL binds RAC1:GTP BibTex
2020-02-04 R-HSA-9673346 Unknown kinase phosphorylates p-DVL BibTex
2020-02-04 R-HSA-9673296 WNT5:FZD7 binds p-DVL BibTex
2020-02-04 R-HSA-9673349 WNT5 binds FZD7 BibTex
2020-02-04 R-HSA-9664285 IgG binds the surface of the amastigote form of Leishmania BibTex
2020-02-04 R-MMU-9670578 Mouse IgG binds LPG1G2 in the amastigote form of Leishmania BibTex
2020-02-04 R-HSA-9664397 IgG binds LPG1G2 in the amastigote form of Leishmania BibTex
2020-02-04 R-HSA-9664268 Opsonized leishmania amastigote binds FCGR3 BibTex
2020-02-04 R-HSA-9664275 Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers BibTex
2020-02-04 R-HSA-9664273 SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers BibTex
2020-02-04 R-HSA-9664261 Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK BibTex
2020-02-04 R-HSA-9664270 Recruitment of PLCgamma to membrane due to FCGR3A effect BibTex
2020-02-04 R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect BibTex
2020-02-04 R-HSA-9664271 Release of PLCG from FCGR3A BibTex
2020-02-04 R-HSA-9660829 ADORA2B binds Ade-Rib BibTex
2020-02-04 R-HSA-9660828 ADORA2B:Ade-Rib binds heterometric G-protein Gs BibTex
2020-02-04 R-HSA-9660824 ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs BibTex
2020-02-04 R-HSA-9660819 ADORA2B:Ade-Rib:GsGTP dissociates BibTex
2020-02-04 R-HSA-9666435 VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK BibTex
2020-02-04 R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 BibTex
2020-02-04 R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP BibTex
2020-02-04 R-HSA-9666426 CRKII:DOCK180:ELMO binds FCGR3A BibTex
2020-02-04 R-HSA-9666428 DOCK180 exchanges GTP for GDP on RAC1:GDP BibTex
2020-02-04 R-HSA-9670156 PtdIns(4,5)P2 binds WASP, N-WASP BibTex
2020-02-04 R-HSA-9670155 CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP BibTex
2020-02-04 R-HSA-9665524 ATP translocates from cytosol to extracellular space (stimuated by C3AR1:C3a) BibTex
2020-02-04 R-HSA-9664332 CREB1 binds IL-10 promoter BibTex
2020-02-04 R-HSA-9664346 IL10 gene produces IL10 protein BibTex
2020-02-04 R-HSA-9662747 iRHOM2 transports ADAM17 from ER to the Golgi-network BibTex
2020-02-04 R-HSA-9662786 FURIN cleaves ADAM17 BibTex
2020-02-04 R-HSA-9662773 ADAM17 binds Zn2+ BibTex
2020-02-04 R-HSA-9662818 iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane BibTex
2020-02-04 R-HSA-9662823 PLK2, MAPK14 phosphorylate ADAM17 BibTex
2020-02-04 R-HSA-9662781 CD163 gene produces CD163 protein BibTex
2020-02-04 R-HSA-9662837 p-S,T-ADAM17(215-827):Zn2+ cleaves CD163 BibTex
2020-02-04 R-HSA-9665525 sCD163 translocates from extracellular region to cytosol BibTex
2020-02-04 R-HSA-9663426 sCD163 binds MYH9 in T-cells BibTex
2020-02-04 R-HSA-9664306 LTC4 binds CyslTR1,2 BibTex
2020-02-04 R-HSA-9662708 CREB binds IL6 promoter BibTex
2020-02-04 R-HSA-9662710 IL6 gene produces IL6 protein BibTex
2020-02-04 R-HSA-9666433 IgG binds the surface of the amastigote form of Leishmania BibTex
2020-02-04 R-HSA-9664406 IgG:Lma antigens binds FCGR3A:CD3 dimers BibTex
2020-02-04 R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole BibTex
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