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Evripidis Gavathiotis

 ORCID
https://orcid.org/0000-0001-6319-8331
Reviewed Reactions (48)
Date Identifier Reaction Reference
2020-05-04 R-HSA-9656207 CR2 RAF1 mutants don't bind YWHAB BibTex
2020-05-04 R-HSA-9656209 Dissociation of RAS:RAF1 mutant complex BibTex
2020-05-04 R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants BibTex
2020-05-04 R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer BibTex
2020-05-04 R-HSA-9656211 MAP2Ks and MAPKs bind to the activated mutant RAF1 complex BibTex
2020-05-04 R-HSA-9656212 Phosphorylation of RAF1 mutants BibTex
2020-05-04 R-HSA-9658253 RAS:GTP binds PI3K BibTex
2020-05-04 R-HSA-9647978 pro-RAS proteins are farnesylated BibTex
2020-05-04 R-HSA-9647999 RCE1 cleaves S-Farn proRAS proteins BibTex
2020-05-04 R-HSA-9647977 ICMT methylates S-Farn RAS proteins BibTex
2020-05-04 R-HSA-9649732 Mature S-Farn-Me KRAS4B translocates to plasma membrane BibTex
2020-05-04 R-HSA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated BibTex
2020-05-04 R-HSA-9647980 mature RAS proteins translocate to plasma membrane BibTex
2020-05-04 R-HSA-9649733 mature p21 RAS binds GDP BibTex
2020-05-04 R-HSA-9649735 Intrinsic nucleotide exchange on RAS BibTex
2020-05-04 R-HSA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP BibTex
2020-05-04 R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks BibTex
2020-05-04 R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs BibTex
2020-05-04 R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK BibTex
2020-05-04 R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks BibTex
2020-05-04 R-HSA-9653503 KRAS4B is phosphorylated on serine 181 BibTex
2020-05-04 R-HSA-9653592 pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane BibTex
2020-05-04 R-HSA-9653585 S-Farn-Me KRAS4B binds calmodulin BibTex
2020-05-04 R-HSA-9654521 Calmodulin dissociates KRAS4B from the plasma membrane BibTex
2020-05-04 R-HSA-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ BibTex
2020-05-04 R-HSA-9654523 ARL2:GTP bind PDE6D on KRAS4B BibTex
2020-05-04 R-HSA-9654533 KRAS4B recycles to the plasma membrane BibTex
2020-05-04 R-HSA-9647991 Palmostatin B binds RAS depalmitoylases BibTex
2020-05-04 R-HSA-9653514 USP17L2 deubiquitinates RCE1 BibTex
2020-05-04 R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB BibTex
2020-05-04 R-HSA-9647994 RAS proteins are depalmitoylated BibTex
2020-05-04 R-HSA-9653595 pS181-S-Farn-Me KRAS4B binds BCL2L1 BibTex
2020-05-04 R-HSA-9656775 Cysmethynil binds ICMT:Zn2+ BibTex
2020-05-04 R-HSA-9656781 Deltarasin binds PDE6D BibTex
2020-05-04 R-HSA-8867654 PTPN3 binds p-T183,Y185 MAPK12 BibTex
2020-05-04 R-HSA-9635743 PTPN7 binds p-T,Y-MAPK BibTex
2020-05-04 R-HSA-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs BibTex
2020-05-04 R-HSA-8867658 PTPN3 dephosphorylates MAPK12 BibTex
2020-05-04 R-HSA-8868118 MAPK12 phosphorylates PTPN3 BibTex
2020-05-04 R-HSA-9660557 RAS:GTP binds RAL GDS proteins BibTex
2020-05-04 R-HSA-9653108 Raf dimer inhibitors bind RAF heterodimers BibTex
2020-05-04 R-HSA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs BibTex
2020-05-04 R-HSA-6802834 RAS GTPase mutants don't hydrolyze GTP BibTex
2020-05-04 R-HSA-9652816 Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs BibTex
2020-05-04 R-HSA-9652165 MAP2K mutants constitutively phosphorylate MAPKs BibTex
2020-05-04 R-HSA-9660536 SHOC2 M173I disrupts the SHOC2:MRAS:PP1 complex BibTex
2020-05-04 R-HSA-9660538 Mutant MRAS:SHOC2:PPP1CC complexes dephosphorylate inactive RAFs BibTex
2020-05-04 R-HSA-9656213 RAF1 mutants show enhanced heterodimerization with BRAF BibTex
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