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Steve Jupe

 ORCID
https://orcid.org/0000-0001-5807-0069
Reviewed Reactions (87)
Date Identifier Reaction Reference
2016-08-02 R-HSA-6807578 GNLY binds the bacterial cell surface in the phagosome BibTex
2016-08-02 R-HSA-6807581 HTN5, (HTN1, HTN3) binds fungal SSA1/SSA2 BibTex
2016-08-02 R-HSA-6810643 EPPIN protein complex binds bacteria BibTex
2016-08-02 R-HSA-6806732 GNLY binds the bacterial cell surface BibTex
2016-08-02 R-HSA-6807565 GNLY is transferred to the phagosome BibTex
2016-08-02 R-HSA-6813626 LEAP2 binds bacteria BibTex
2016-08-02 R-HSA-6807144 HTN1,HTN3 or HTN5 binds the bacterial anionic surface BibTex
2012-04-30 R-HSA-1222685 Cathelicidin LL-37 binds to bacterial cell wall BibTex
2016-08-02 R-HSA-6801687 PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) BibTex
2016-08-02 R-HSA-6803104 DCD forms oligomeric complex BibTex
2016-08-02 R-HSA-6810724 PI3 binds the bacterial surface BibTex
2016-08-02 R-HSA-6803047 DCD peptide binds bacterial membrane phospholipids BibTex
2016-08-02 R-HSA-6803060 DCD(63-110) is processed to DCD(63-109) BibTex
2016-08-02 R-HSA-6802999 DCD is processed into DCD(63-110) BibTex
2016-08-02 R-HSA-6807585 BPI binds LPS on the bacterial surface BibTex
2016-08-02 R-HSA-6803063 RNASEs bind bacterial LPS, PGN BibTex
2016-08-02 R-HSA-8862771 PLA2G2A binds bacterial phospholipids BibTex
2016-08-02 R-HSA-6809521 BPIF binds bacteria BibTex
2016-08-02 R-HSA-6798489 S100A7 or S100A7A binds Zn2+ BibTex
2016-08-02 R-HSA-6798474 S100A8:S100A9 binds Zn2+ BibTex
2016-08-02 R-HSA-6798528 S100A8:S100A9 binds Mn2+ BibTex
2016-08-02 R-HSA-6808566 CHGA-derived peptide binds the bacterial cell surface BibTex
2016-08-02 R-HSA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen BibTex
2016-08-02 R-HSA-6799959 PGLYRP3,4 binds bacterial peptidoglycan BibTex
2016-08-02 R-HSA-6804527 INTL1 binds bacterial glycans BibTex
2016-08-02 R-HSA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall BibTex
2016-08-02 R-HSA-8862300 LYZ binds bacterial peptidoglycan BibTex
2016-08-02 R-HSA-6801808 REG3A,REG3G binds bacterial peptidoglycan BibTex
2016-08-02 R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan BibTex
2016-08-02 R-HSA-6813659 ELANE, CTSG or PRTN3 binds bacteria BibTex
2016-08-02 R-HSA-6789072 PGLYRP1 binds bacterial peptidoglycan BibTex
2016-08-02 R-HSA-6799981 PGLYRP2 binds bacterial peptidoglycan BibTex
2016-08-02 R-HSA-6801762 REG3A oligomerize to form a pore complex BibTex
2016-08-02 R-HSA-6801776 REG3A binds bacterial phospholipids BibTex
2016-08-02 R-HSA-6801766 Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) BibTex
2016-02-12 R-MMU-8849847 St14 hydrolyzes and activates Klk5 BibTex
2016-02-08 R-HSA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) BibTex
2015-04-14 R-HSA-5684273 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 BibTex
2015-04-14 R-HSA-5684250 SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 BibTex
2015-04-14 R-HSA-5684248 SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 BibTex
2015-04-14 R-HSA-5684261 MAP3K8 is phosphorylated BibTex
2015-04-14 R-HSA-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex BibTex
2015-04-14 R-HSA-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 BibTex
2012-11-07 R-GGA-2132221 C5b:C6:C7:C8 and C9 bind to form membrane attack complex (MAC) BibTex
2012-11-07 R-GGA-2530584 CREM (CREMP) binds to surface-bound C3b or C4b BibTex
2012-11-07 R-GGA-2132283 Factor H binds to host cell surface BibTex
2012-11-07 R-GGA-2530591 CREG (CR1L) causes dissociation of C3 convertases BibTex
2012-11-07 R-GGA-2132088 Vitronectin prevents C9 polymerization BibTex
2012-11-07 R-GGA-2132247 CD59 binds C5b:C6:C7:C8 BibTex
2012-11-07 R-GGA-2132094 C8 binds to C5b:C6:C7 complement complex BibTex
2012-11-07 R-GGA-2132133 C5b:C6:C7 inserts into the target cell membrane BibTex
2012-11-07 R-GGA-2530573 CREG(CR1L) binds to surface-bound C3 convertases BibTex
2012-11-07 R-GGA-2132136 Vitronectin binds to C5b-C7 complex BibTex
2012-11-07 R-GGA-2132047 Spontaneous hydrolysis of an internal thioester bond in complement factor C3 BibTex
2012-11-07 R-GGA-2132104 Complement factor B binds to the hydrolyzed form of C3 BibTex
2012-11-07 R-GGA-2132100 Fluid-phase proteolytic cleavage of factor B BibTex
2012-11-07 R-GGA-2132064 Antigen bound antibody interacts with C1complement complex BibTex
2012-11-07 R-GGA-2132122 Activation of C1r within the C1complement complex BibTex
2012-11-07 R-GGA-2132065 C1r activates C1s component within C1 complement complex BibTex
2012-11-07 R-GGA-2132187 MBL or ficolin binds an oligosaccharide pattern on the target cell surface BibTex
2012-11-07 R-GGA-2132206 MASPs activation BibTex
2012-11-07 R-GGA-2132233 Proteolytic cleavage of complement factor C4 BibTex
2012-11-07 R-GGA-2132248 C4b binds to target cell surface BibTex
2012-11-07 R-GGA-2132096 Formation of C4b:factor B complex BibTex
2012-11-07 R-GGA-2132222 Cleavage of factor B to form classical C3 convertase BibTex
2012-11-07 R-GGA-2173323 Cleavage of C3 by fluid-phase C3i:factor B BibTex
2012-11-07 R-GGA-2132210 C3b fragment binds to the target cell surface BibTex
2012-11-07 R-GGA-2132061 Complement factor B binds to surface-bound C3b fragment BibTex
2012-11-07 R-GGA-2132074 Cleavage of surface-bound factor B BibTex
2012-11-07 R-GGA-2132085 Cleavage of C3 by surface-bound C3 convertases BibTex
2012-11-07 R-GGA-2173317 C3a anaphylatoxin binds C3a receptor BibTex
2012-11-07 R-GGA-2132264 Formation of alternate C5 convertase BibTex
2012-11-07 R-GGA-2132269 Formation of classical C5 convertase BibTex
2012-11-07 R-GGA-2132278 Cleavage of C5 by C5 convertases BibTex
2012-11-07 R-GGA-2173318 C5a anaphylatoxin binds C5a receptor BibTex
2012-11-07 R-GGA-2132201 Opsonization with C3b or C4b BibTex
2012-11-07 R-GGA-2859050 Hydrolysis of C4b BibTex
2012-11-07 R-GGA-2132261 Complement factor H binds to C3b BibTex
2012-11-07 R-GGA-2132276 Complement factor I inactivates C3b BibTex
2012-11-07 R-GGA-2530565 iC3b proteolysis BibTex
2012-11-07 R-GGA-2132277 Complement factor H binds to surface-bound C3b BibTex
2012-11-07 R-GGA-2132271 Factor H displaces Bb in Cb:Bb complex BibTex
2012-11-07 R-GGA-2132260 Complement factor I inactivates surface-bound C3b BibTex
2012-11-07 R-GGA-2132284 Formation of C5b:C6 BibTex
2012-11-07 R-GGA-2132060 Formation of C5b:C6:C7 BibTex
2010-06-07 R-HSA-397891 Dissociation of the PAR:G12/13 complex BibTex
2009-03-10 R-HSA-164381 G alpha (s) auto-inactivates by hydrolysing GTP to GDP BibTex