Francisco Rivero Crespo

 ORCID
https://orcid.org/0000-0001-5435-6991
Affiliation
The Hull York Medical School
Authored Pathways (14/14)
Date Identifier Pathway Reference
2020-10-13 R-HSA-9706019 RHOBTB3 ATPase cycle BibTex
2014-12-26 R-HSA-195258 RHO GTPase Effectors BibTex
2014-12-26 R-HSA-5666185 RHO GTPases Activate Rhotekin and Rhophilins BibTex
2014-12-26 R-HSA-5627083 RHO GTPases regulate CFTR trafficking BibTex
2014-12-26 R-HSA-5668599 RHO GTPases Activate NADPH Oxidases BibTex
2014-12-26 R-HSA-5625886 Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 BibTex
2014-12-26 R-HSA-5625740 RHO GTPases activate PKNs BibTex
2014-12-26 R-HSA-5625900 RHO GTPases activate CIT BibTex
2014-12-26 R-HSA-5626467 RHO GTPases activate IQGAPs BibTex
2014-12-26 R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs BibTex
2014-12-26 R-HSA-5625970 RHO GTPases activate KTN1 BibTex
2014-12-26 R-HSA-5627123 RHO GTPases activate PAKs BibTex
2014-12-26 R-HSA-5627117 RHO GTPases Activate ROCKs BibTex
2014-12-26 R-HSA-5663220 RHO GTPases Activate Formins BibTex
Authored Reactions (93/93)
Date Identifier Reaction Reference
2020-10-13 R-HSA-9706399 RHOBTB3 hydrolyzes ATP BibTex
2020-10-13 R-HSA-9706393 RHOBTB3 binds ATP BibTex
2020-10-13 R-HSA-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network BibTex
2014-12-26 R-HSA-5666216 RHOA:GTP:RTKN binds TAX1BP3 BibTex
2014-12-26 R-NUL-5667039 RHPN2 binds RHOB:GTP BibTex
2014-12-26 R-HSA-5667037 RHPN2 binds RHOB:GTP BibTex
2014-12-26 R-MMU-5667058 Ropn1 binds RhoA:GTP:Rhpn1 BibTex
2014-12-26 R-HSA-5667052 ROPN1 binds RHOA:GTP:RHPN1 BibTex
2014-12-26 R-HSA-5667008 RHOA:GTP binds RHPN1 or RHPN2 BibTex
2014-12-26 R-MMU-5666183 Rtkn binds RhoA, RhoC or RhoB BibTex
2014-12-26 R-HSA-5666178 RTKN binds RHOA, RHOC or RHOB BibTex
2014-12-26 R-HSA-5666197 RHOA:GTP:RTKN binds LIN7B BibTex
2014-12-26 R-HSA-5627275 GOPC promotes translocation of CFTR to lysosomes BibTex
2014-12-26 R-HSA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane BibTex
2014-12-26 R-HSA-5627072 RHOQ binds GOPC:CFTR BibTex
2014-12-26 R-HSA-5671993 CIT-3 binds DLG4 BibTex
2014-12-26 R-MMU-8981447 Cit-3 binds activated Rhoa, Rhob, Rhoc and Rac1 BibTex
2014-12-26 R-HSA-8981443 CIT-3 binds activated RHOA, RHOB, RHOC and RAC1 BibTex
2014-12-26 R-HSA-5671970 Activated CIT binds KIF14 and PRC1 BibTex
2014-12-26 R-MMU-5671980 Cit binds Cdkn1b BibTex
2014-12-26 R-HSA-5671972 CIT binds CDKN1B BibTex
2014-12-26 R-HSA-5671772 p-T38-PPP1R14A binds MLCP BibTex
2014-12-26 R-HSA-5671763 p-T774-PKN1 phosphorylates PPP1R14A BibTex
2014-12-26 R-HSA-5625883 PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 BibTex
2014-12-26 R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters BibTex
2014-12-26 R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters BibTex
2014-12-26 R-HSA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters BibTex
2014-12-26 R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters BibTex
2014-12-26 R-HSA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters BibTex
2014-12-26 R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters BibTex
2014-12-26 R-HSA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes BibTex
2014-12-26 R-HSA-5625745 PKN1 stimulates association of AR with NCOA2 BibTex
2014-12-26 R-HSA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus BibTex
2014-12-26 R-HSA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) BibTex
2014-12-26 R-HSA-5668714 RAC1:GTP binds NOX1 complex BibTex
2014-12-26 R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen BibTex
2014-12-26 R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen BibTex
2014-12-26 R-HSA-5668735 RAC1:GTP binds NOX3 complex BibTex
2014-12-26 R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP BibTex
2014-12-26 R-HSA-5668605 RAC2:GTP binds NOX2 complex BibTex
2014-12-26 R-HSA-5672329 IQGAP1 binds CLIP1 and microtubules BibTex
2014-12-26 R-HSA-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 BibTex
2014-12-26 R-HSA-5626549 IQGAPs bind CALM1 BibTex
2014-12-26 R-HSA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin BibTex
2014-12-26 R-HSA-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs BibTex
2014-12-26 R-HSA-5672083 KTN1 binds Kinesin-1 BibTex
2014-12-26 R-HSA-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) BibTex
2014-12-26 R-MMU-442844 Pak3 phosphorylates Cttn BibTex
2014-12-26 R-HSA-442832 PAK phosphorylates cortactin BibTex
2014-12-26 R-HSA-5669250 PAK1 phosphorylates FLNA BibTex
2014-12-26 R-HSA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) BibTex
2014-12-26 R-HSA-5669158 NF2 binds PAK1 BibTex
2014-12-26 R-HSA-5669240 FLNA binds PAK1 BibTex
2014-12-26 R-HSA-5668984 PAK1 or PAK2 phosphorylates MYLK BibTex
2014-12-26 R-NUL-5671959 Activated Cit phosphorylates MRLCs of myosin II complex BibTex
2014-12-26 R-HSA-5671749 p-T774-PKN1 phosphorylates CDC25C BibTex
2014-12-26 R-HSA-5671737 p-T774-PKN1 binds CDC25C BibTex
2014-12-26 R-HSA-5623667 PDPK1 phosphorylates PKN1,2,3 BibTex
2014-12-26 R-HSA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 BibTex
2014-12-26 R-HSA-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 BibTex
2014-12-26 R-HSA-5665989 DIAPH1 binds RHOA:GTP BibTex
2014-12-26 R-HSA-5665686 FMNL1 binds CDC42:GTP BibTex
2014-12-26 R-MMU-5665684 Fmnl1 binds Cdc42:GTP BibTex
2014-12-26 R-HSA-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes BibTex
2014-12-26 R-HSA-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin BibTex
2014-12-26 R-HSA-5665727 FMNL2 binds CDC42:GTP BibTex
2014-12-26 R-HSA-5665748 FMNL2 binds RHOC:GTP BibTex
2014-12-26 R-HSA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments BibTex
2014-12-26 R-HSA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin BibTex
2014-12-26 R-HSA-5665659 RAC1:GTP:FMNL1 binds profilin:G-actin BibTex
2014-12-26 R-HSA-5663232 FMNL1 binds RAC1:GTP BibTex
2014-12-26 R-MMU-5663241 Fmnl1 binds Rac1:GTP BibTex
2014-12-26 R-MMU-5665656 Rac1:GTP:Fmnl1 binds Pfn1,Pfn2 BibTex
2014-12-26 R-HSA-5666001 Profilin:G-actin binds MKL1 BibTex
2014-12-26 R-HSA-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores BibTex
2014-12-26 R-HSA-5666008 SCAI binds SRF:MKL1 BibTex
2014-12-26 R-HSA-5665998 MKL1 binds SRF BibTex
2014-12-26 R-HSA-5665999 MKL1 translocates from cytosol to the nucleus BibTex
2014-12-26 R-HSA-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 BibTex
2014-12-26 R-HSA-5666049 SRF:MKL1 stimulate ITGB1 expression while SCAI inhibits it BibTex
2014-12-26 R-HSA-5666046 SRF:MKL1 binds ITGB1 Gene BibTex
2014-12-26 R-HSA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores BibTex
2014-12-26 R-HSA-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes BibTex
2014-12-26 R-HSA-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes BibTex
2014-12-26 R-HSA-5665767 Activated FMNL3 binds G-actin BibTex
2014-12-26 R-HSA-5665761 FMNL3 binds RHOC:GTP BibTex
2014-12-26 R-HSA-5668978 MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex BibTex
2014-12-26 R-MGA-5672766 Turkey MYLK phosphorylates MRLCs of the non-muscle myosin II complex BibTex
2014-12-26 R-HSA-5668947 PAK1 phosphorylates myosin phosphatase BibTex
2014-12-26 R-HSA-5627775 Autophosphorylation of PAK1,2,3 BibTex
2014-12-26 R-HSA-5671919 Activated CIT phosphorylates MRLCs BibTex
2014-12-26 R-HSA-5625901 CIT (citron kinase) binds activated RHOA, RHOB, RHOC and RAC1 BibTex
2014-12-26 R-MMU-5625893 Cit binds activated Rhoa, Rhob, Rhoc and Rac1 BibTex
Reviewed Pathways (3/3)
Date Identifier Pathway Reference
2020-10-13 R-HSA-9706574 RHOBTB GTPase Cycle BibTex
2020-10-13 R-HSA-9013422 RHOBTB1 GTPase cycle BibTex
2020-10-13 R-HSA-9013418 RHOBTB2 GTPase cycle BibTex
Reviewed Reactions (36/36)
Date Identifier Reaction Reference
2020-10-13 R-HSA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane BibTex
2020-10-13 R-HSA-9018774 RHOBTB1 binds GTP BibTex
2020-10-13 R-HSA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane BibTex
2020-10-13 R-HSA-9018785 RHOBTB2 binds GTP BibTex
2014-12-26 R-HSA-389788 Activation of PAKs by RAC1 and CDC42 BibTex
2014-12-26 R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen BibTex
2014-12-26 R-HSA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 BibTex
2014-12-26 R-HSA-419083 Myosin phosphatase inactivation by ROCK BibTex
2014-12-26 R-HSA-419087 LIM kinase phosphorylation by ROCK BibTex
2014-12-26 R-NUL-421733 ROCK1 phosphorylates LIMK2 (rat) BibTex
2014-12-26 R-HSA-2029473 Branching and elongation of mother and daughter filaments BibTex
2014-12-26 R-HSA-2197690 Detachment of WASP/WAVE BibTex
2014-12-26 R-HSA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin BibTex
2014-12-26 R-HSA-442592 WASPs or WAVEs activate the ARP2/3 complex BibTex
2014-12-26 R-NUL-442561 WASP/N-WASP activate the Arp2/3 complex BibTex
2014-12-26 R-HSA-2197698 Src phosphorylate WASP,N-WASP BibTex
2014-12-26 R-HSA-2197691 WIP binds WASP,N-WASP, activating them BibTex
2014-12-26 R-HSA-442586 Activation of WASP and N-WASP by CDC42 BibTex
2014-12-26 R-MMU-442572 Activation of WASP and N-WASP by CDC42 BibTex
2014-12-26 R-HSA-2029469 p-ERK phosphorylates WAVEs and ABI BibTex
2014-12-26 R-HSA-2130194 ABL phosphorylates WAVEs BibTex
2014-12-26 R-HSA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) BibTex
2014-12-26 R-HSA-2029460 PAK1 phosphorylates LIMK1 BibTex
2014-12-26 R-HSA-419232 Myosin phosphatase dephosphorylates myosin regulatory light chain BibTex
2014-12-26 R-MGA-421635 Myosin phosphatase dephosphorylates myosin regulatory light chain BibTex
2014-12-26 R-HSA-419197 Myosin regulatory light chain phosphorylation by ROCK BibTex
2014-12-26 R-HSA-419049 ROCK activation by RHO BibTex
2014-12-26 R-HSA-3858489 ppDVL binds DAAM1 BibTex
2014-12-26 R-HSA-3858495 DAAM1 recruits GTP-bound RHOA BibTex
2014-12-26 R-HSA-203070 Association of profilin with monomeric actin BibTex
2014-12-26 R-HSA-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 BibTex
2014-12-26 R-HSA-8981931 RAC1 and CDC42 activate PAK2 BibTex
2014-12-26 R-HSA-445797 MYLK (MLCK) Active Calmodulin Binding BibTex
2014-12-26 R-HSA-2029454 Autophosphorylation of PAK1 BibTex
2014-12-26 R-HSA-2029456 RAC1 and CDC42 activate PAK1 BibTex
2014-12-26 R-HSA-8981926 RAC1 and CDC42 activate PAK3 BibTex
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