Reactome | PP2A (PPP2CA:PPP2R2A:PPP2R1A,B) [cytosol]

PP2A (PPP2CA:PPP2R2A:PPP2R1A,B) [cytosol]

Stable Identifier

R-XTR-9865241

Type

Complex

Species

Xenopus tropicalis

Compartment

cytosol

Locations in the PathwayBrowser

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Cellular responses to stimuli (Xenopus tropicalis)

- Cellular responses to mechanical stimuli (Xenopus tropicalis)
  - Response of endothelial cells to shear stress (Xenopus tropicalis)
    - Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Xenopus tropicalis)
      - PP2A dephosphorylates serine-127 of YAP1 (Xenopus tropicalis)
        
        p-S26-ANXA2:PP2A:p-S715-PDE4D5:ITGA5:ITGB1:fibronectin [plasma membrane] (Xenopus tropicalis)
        
        PP2A (PPP2CA:PPP2R2A:PPP2R1A,B) [cytosol] (Xenopus tropicalis)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Participates

as a component of

p-S26-ANXA2:PP2A:p-S715-PDE4D5:ITGA5:ITGB1:fibronectin [plasma membrane] (Xenopus tropicalis)

Inferred From

PP2A (PPP2CA:PPP2R2A:PPP2R1A,B) [cytosol] (Homo sapiens)

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