Reactome | GRIN1:GRIN2A di-heterotetramer [plasma membrane]

GRIN1:GRIN2A di-heterotetramer [plasma membrane]

Stable Identifier

R-XTR-9610679

Type

Complex

Species

Xenopus tropicalis

Compartment

plasma membrane

Locations in the PathwayBrowser

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Neuronal System (Xenopus tropicalis)

- Transmission across Chemical Synapses (Xenopus tropicalis)
  - Neurotransmitter receptors and postsynaptic signal transmission (Xenopus tropicalis)
    - Activation of NMDA receptors and postsynaptic events (Xenopus tropicalis)
      - Assembly and cell surface presentation of NMDA receptors (Xenopus tropicalis)
        
        GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Xenopus tropicalis)
        
        GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Xenopus tropicalis)
      - Unblocking of NMDA receptors, glutamate binding and activation (Xenopus tropicalis)
        
        Ca2+ influx into the post-synaptic cell (Xenopus tropicalis)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2 NMDA receptors [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Xenopus tropicalis)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Participates

as an output of

GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Xenopus tropicalis)

as a member of

GRIN1:GRIN2 NMDA receptors [plasma membrane] (Xenopus tropicalis)

Inferred From

GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)

GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)

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