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Go!
pten [cytosol]
Stable Identifier
R-XTR-8948777
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
K48polyUb-K289-PTEN, B1H2U0
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
PTEN Regulation (Xenopus tropicalis)
Regulation of PTEN stability and activity (Xenopus tropicalis)
MKRN1 polyubiquitinates PTEN (Xenopus tropicalis)
pten [cytosol] (Xenopus tropicalis)
Proteasome degrades polyubiquitinated PTEN (Xenopus tropicalis)
PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (Xenopus tropicalis)
pten [cytosol] (Xenopus tropicalis)
USP13 and OTUD3 deubiquitinate PTEN (Xenopus tropicalis)
pten [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:B1H2U0
Gene Names
pten
Reference Genes
BioGPS Gene:100144716 pten
ENSEMBL:ENSXETG00000009268
KEGG Gene (Xenopus tropicalis):100144716 pten
Monarch:100144716 pten
NCBI Gene:100144716 pten
Reference Transcript
RefSeq:NM_001123471.1 pten
Other Identifiers
100144716
GO:0003824
GO:0004438
GO:0004721
GO:0004722
GO:0004725
GO:0005634
GO:0005654
GO:0005737
GO:0006629
GO:0006915
GO:0007399
GO:0008138
GO:0008285
GO:0012501
GO:0014069
GO:0016311
GO:0016314
GO:0016605
GO:0016787
GO:0016791
GO:0017018
GO:0042995
GO:0043197
GO:0043226
GO:0046856
GO:0048856
GO:0051717
GO:0051800
GO:0052866
GO:0140096
Participates
as a member of
PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (Xenopus tropicalis)
as an output of
MKRN1 polyubiquitinates PTEN (Xenopus tropicalis)
as an input of
USP13 and OTUD3 deubiquitinate PTEN (Xenopus tropicalis)
Other forms of this molecule
pten [cytosol]
phospho-pten [cytosol]
phospho-pten [cytosol]
phospho-pten [cytosol]
phospho-pten [cytosol]
pten [cytosol]
pten [cytosol]
pten [nucleoplasm]
pten [nucleoplasm]
pten [cytosol]
Inferred From
PolyUb-PTEN,K48polyUb-K289-PTEN [cytosol]
(Homo sapiens)
K48polyUb-K289-PTEN [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 289 (in Homo sapiens)
Coordinate
289
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_001116943.1
Xenbase
XB-GENE-491433
Ensembl
ENSXETG00000009268
,
ENSXETP00000106951
,
ENSXETT00000106006
,
ENSXETT00000020363
,
ENSXETP00000020363
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