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pik3r2 [cytosol]
Stable Identifier
R-XTR-74791
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
PIK3R2, A0A6I8Q186
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
RET signaling (Xenopus tropicalis)
p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Xenopus tropicalis)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Xenopus tropicalis)
PI3K alpha, beta, gamma [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K alpha, beta, gamma [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Hemostasis (Xenopus tropicalis)
Cell surface interactions at the vascular wall (Xenopus tropicalis)
Tie2 Signaling (Xenopus tropicalis)
Interaction of Tie2 and p85 of PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p85 bound to Tie2 [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Platelet activation, signaling and aggregation (Xenopus tropicalis)
GPVI-mediated activation cascade (Xenopus tropicalis)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Xenopus tropicalis)
PI3K alpha, beta, gamma [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Costimulation by the CD28 family (Xenopus tropicalis)
CD28 co-stimulation (Xenopus tropicalis)
CD28 dependent PI3K/Akt signaling (Xenopus tropicalis)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
CD28:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K binds CD28 (Xenopus tropicalis)
CD28:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K binds ICOS (Xenopus tropicalis)
ICOS:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Xenopus tropicalis)
Regulation of signaling by CBL (Xenopus tropicalis)
CBL ubiquitinates PI3K (Xenopus tropicalis)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Xenopus tropicalis)
PI3K alpha, beta, gamma [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K beta [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
Role of LAT2/NTAL/LAB on calcium mobilization (Xenopus tropicalis)
PI3K associates with phosphorylated GAB2 (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Phosphorylation of PIP2 to PIP3 by PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Phospholipid metabolism (Xenopus tropicalis)
PI Metabolism (Xenopus tropicalis)
Synthesis of PIPs at the plasma membrane (Xenopus tropicalis)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Xenopus tropicalis)
PIK3C(1) [cytosol] (Xenopus tropicalis)
PIK3CA:PIK3R2 [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R2 [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Xenopus tropicalis)
PIK3(2) [cytosol] (Xenopus tropicalis)
PIK3CA:PIK3R2 [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PIK3CB:PIK3R2 [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
Negative regulation of the PI3K/AKT network (Xenopus tropicalis)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
CD28:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
ICOS:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
CD28:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
ICOS:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC1,RAC2,RHOG activate PI3K (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
RAS:GTP binds PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p21 RAS:GTP:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (q) signalling events (Xenopus tropicalis)
G alpha (q) inhibits PI3K alpha (Xenopus tropicalis)
G-protein alpha (q/11):PI3K alpha [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by ALK (Xenopus tropicalis)
PI3K synthesizes PIP3 downstream of ALK (Xenopus tropicalis)
Active ALK:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by Insulin receptor (Xenopus tropicalis)
Insulin receptor signalling cascade (Xenopus tropicalis)
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
PI3K-containing complexes [cytosol] (Xenopus tropicalis)
Activated FGFR bound to PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by LTK (Xenopus tropicalis)
Active LTK receptor binds PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-5Y LTK dimer:ALKAL1,2:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by NTRKs (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
PI3K/AKT activation (Xenopus tropicalis)
Active IRS recruits PI3K to the plasma membrane and activates it (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K produces PIP3 and other phosphatidyl inositides (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by PDGF (Xenopus tropicalis)
Downstream signal transduction (Xenopus tropicalis)
PI3-kinase binds to the active receptor (Xenopus tropicalis)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Xenopus tropicalis)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by SCF-KIT (Xenopus tropicalis)
Direct recruitment of PI3K to p-KIT (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Synthesis of PIP3 from PIP2 by PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Xenopus tropicalis)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Xenopus tropicalis)
IGF1R signaling cascade (Xenopus tropicalis)
IRS-related events triggered by IGF1R (Xenopus tropicalis)
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
PI3K-containing complexes [cytosol] (Xenopus tropicalis)
Activated FGFR bound to PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase cycle (Xenopus tropicalis)
CDC42 GTPase cycle (Xenopus tropicalis)
CDC42 GAPs stimulate CDC42 GTPase activity (Xenopus tropicalis)
CDC42 GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC1 GTPase cycle (Xenopus tropicalis)
RAC1 GAPs stimulate RAC1 GTPase activity (Xenopus tropicalis)
RAC1 GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC1 binds effectors at the plasma membrane (Xenopus tropicalis)
RAC1 effectors [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC1:GTP:RAC1 effectors [plasma membrane] (Xenopus tropicalis)
RAC1 effectors [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC2 GTPase cycle (Xenopus tropicalis)
RAC2 GAPs stimulate RAC2 GTPase activity (Xenopus tropicalis)
RAC2 GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC2 binds effectors at the plasma membrane (Xenopus tropicalis)
RAC2 plasma membrane effectors [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Xenopus tropicalis)
RAC2 plasma membrane effectors [cytosol] (Xenopus tropicalis)
PI3K alpha [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RAC3 GTPase cycle (Xenopus tropicalis)
RAC3 GAPs stimulate RAC3 GTPase activity (Xenopus tropicalis)
RAC3 GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RHOA GTPase cycle (Xenopus tropicalis)
RHOA GAPs stimulate RHOA GTPase activity (Xenopus tropicalis)
RHOA GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RHOB GTPase cycle (Xenopus tropicalis)
RHOB GAPs stimulate RHOB GTPase activity (Xenopus tropicalis)
RHOB GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RHOD GTPase cycle (Xenopus tropicalis)
RHOD GAPs stimulate RHOD GTPase activity (Xenopus tropicalis)
RHOD GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RHOF GTPase cycle (Xenopus tropicalis)
RHOF GAPs stimulate RHOF GTPase activity (Xenopus tropicalis)
RHOF GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RHOJ GTPase cycle (Xenopus tropicalis)
RHOJ GAPs stimulate RHOJ GTPase activity (Xenopus tropicalis)
RHOJ GAPs [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RHOU GTPase cycle (Xenopus tropicalis)
RHOU binds effectors at the plasma membrane (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RHOU:GTP:RHOU effectors [plasma membrane] (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RND1 GTPase cycle (Xenopus tropicalis)
RND1 binds effectors (Xenopus tropicalis)
RND1 effectors [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RND1:GTP:RND1 effectors [plasma membrane] (Xenopus tropicalis)
RND1 effectors [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RND3 GTPase cycle (Xenopus tropicalis)
RND3 binds effectors (Xenopus tropicalis)
RND3 effectors [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
RND3:GTP:RND3 effectors [plasma membrane] (Xenopus tropicalis)
RND3 effectors [cytosol] (Xenopus tropicalis)
pik3r2 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A6I8Q186
Gene Names
pik3r2
Reference Genes
BioGPS Gene:100497001 pik3r2
ENSEMBL:ENSXETG00000012933
KEGG Gene (Xenopus tropicalis):100497001 pik3r2
Monarch:100497001 pik3r2
NCBI Gene:100497001 pik3r2
Reference Transcript
RefSeq:XM_004910981.4 pik3r2
RefSeq:XM_002934809.5 pik3r2
RefSeq:XM_031905196.1 pik3r2
Other Identifiers
100497001
GO:0007165
GO:0023052
Participates
as a candidate of
RHOA GAPs [cytosol] (Xenopus tropicalis)
RND3 effectors [cytosol] (Xenopus tropicalis)
CDC42 GAPs [cytosol] (Xenopus tropicalis)
RAC2 GAPs [cytosol] (Xenopus tropicalis)
RHOD GAPs [cytosol] (Xenopus tropicalis)
RAC1 GAPs [cytosol] (Xenopus tropicalis)
RHOF GAPs [cytosol] (Xenopus tropicalis)
RHOB GAPs [cytosol] (Xenopus tropicalis)
RHOJ GAPs [cytosol] (Xenopus tropicalis)
RAC3 GAPs [cytosol] (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
RND1 effectors [cytosol] (Xenopus tropicalis)
PI3K-regulatory subunits [cytosol] (Xenopus tropicalis)
as a component of
PIK3CB:PIK3R2 [cytosol] (Xenopus tropicalis)
PIK3CA:PIK3R2 [cytosol] (Xenopus tropicalis)
as a member of
PI3K-regulatory subunit [cytosol] (Xenopus tropicalis)
Other forms of this molecule
pik3r2 [cytosol]
Inferred From
PIK3R2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_002934855.2
,
XP_004911038.1
,
XP_031761056.1
Xenbase
XB-GENE-6077418
Ensembl
ENSXETG00000012933
,
ENSXETT00000070392
,
ENSXETP00000066372
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