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What is Reactome ?
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Ub [nucleoplasm]
Stable Identifier
R-XTR-68524
Type
Set [DefinedSet]
Species
Xenopus tropicalis
Compartment
nucleoplasm
Synonyms
Ubiquitin, UBIQ_HUMAN
Locations in the PathwayBrowser
Expand all
Cell Cycle (Xenopus tropicalis)
Cell Cycle Checkpoints (Xenopus tropicalis)
G1/S DNA Damage Checkpoints (Xenopus tropicalis)
p53-Independent G1/S DNA Damage Checkpoint (Xenopus tropicalis)
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A (Xenopus tropicalis)
Proteolytic degradation of ubiquitinated-Cdc25A (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitination of phosphorylated CDC25A (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Cell Cycle, Mitotic (Xenopus tropicalis)
Regulation of mitotic cell cycle (Xenopus tropicalis)
APC/C-mediated degradation of cell cycle proteins (Xenopus tropicalis)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Xenopus tropicalis)
APC/C:Cdh1 polyubiquitinates SKP2 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
APC/C:Cdh1-mediated degradation of Skp2 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Autodegradation of Cdh1 by Cdh1:APC/C (Xenopus tropicalis)
Degradation of multiubiquitinated Cdh1 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Multiubiquitination of APC/C-associated Cdh1 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular Senescence (Xenopus tropicalis)
Senescence-Associated Secretory Phenotype (SASP) (Xenopus tropicalis)
Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Xenopus tropicalis)
Ub-EHMT1 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub-EHMT2 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
KEAP1-NFE2L2 pathway (Xenopus tropicalis)
Nuclear events mediated by NFE2L2 (Xenopus tropicalis)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Xenopus tropicalis)
NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub,pS335,S338,T NFE2L2 is degraded (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Cellular response to hypoxia (Xenopus tropicalis)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Xenopus tropicalis)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
DNA Repair (Xenopus tropicalis)
DNA Damage Bypass (Xenopus tropicalis)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Xenopus tropicalis)
Termination of translesion DNA synthesis (Xenopus tropicalis)
KIAA0101 double monoubiquitination (Xenopus tropicalis)
MonoUb:K15,K24-KIAA0101 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Translesion Synthesis by POLH (Xenopus tropicalis)
RCHY1 monoubiquitinates POLH (Xenopus tropicalis)
MonoUb:K682,K686,K694,K709-POLH [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Xenopus tropicalis)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Xenopus tropicalis)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Xenopus tropicalis)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Xenopus tropicalis)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Xenopus tropicalis)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Xenopus tropicalis)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Xenopus tropicalis)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Translesion synthesis by POLI (Xenopus tropicalis)
POLI incorporates dNMP opposite to damaged DNA base (Xenopus tropicalis)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA homotrimer [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Nucleotide Excision Repair (Xenopus tropicalis)
Global Genome Nucleotide Excision Repair (GG-NER) (Xenopus tropicalis)
DNA Damage Recognition in GG-NER (Xenopus tropicalis)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
PARP1 or PARP2 binds DDB2 at GG-NER site (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
UV-DDB ubiquitinates XPC (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Formation of Incision Complex in GG-NER (Xenopus tropicalis)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Recruitment of XPA and release of CAK (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SUMOylation of XPC (Xenopus tropicalis)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Xenopus tropicalis)
Ub,SUMO:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub,SUMO:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
TFIIH binds GG-NER site to form a verification complex (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Xenopus tropicalis)
Ub:XPC:RAD23:CETN2 [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Xenopus tropicalis)
Dual incision in TC-NER (Xenopus tropicalis)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Xenopus tropicalis)
TC-NER incision complex [nucleoplasm] (Xenopus tropicalis)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Xenopus tropicalis)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Xenopus tropicalis)
TC-NER pre-incision complex [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Xenopus tropicalis)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Formation of TC-NER Pre-Incision Complex (Xenopus tropicalis)
Assembly of the pre-incision complex in TC-NER (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
UVSSA:USP7 deubiquitinates ERCC6 (Xenopus tropicalis)
TC-NER pre-incision complex [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Gap-filling DNA repair synthesis and ligation in TC-NER (Xenopus tropicalis)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Xenopus tropicalis)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
DNA Replication (Xenopus tropicalis)
DNA Replication Pre-Initiation (Xenopus tropicalis)
Assembly of the pre-replicative complex (Xenopus tropicalis)
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated geminin is degraded by the proteasome (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by TP53 (Xenopus tropicalis)
Regulation of TP53 Activity (Xenopus tropicalis)
Regulation of TP53 Activity through Phosphorylation (Xenopus tropicalis)
MDM2 ubiquitinates DYRK2 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Regulation of TP53 Expression and Degradation (Xenopus tropicalis)
Regulation of TP53 Degradation (Xenopus tropicalis)
MDM2 homodimers auto-ubiquitinate (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
RNF34 or RFFL ubiquitinates phosphorylated TP53 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
USP7 deubiquitinates MDM2 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
USP7 deubiquitinates TP53 and counteracts MDM2 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Xenopus tropicalis)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Xenopus tropicalis)
Degradation of SMAD2/3:SMAD4 complex (Xenopus tropicalis)
Ub-p-T-2S-SMAD2,3:SMAD4 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Degradation of ubiquitinated SKI/SKIL (Xenopus tropicalis)
Ub-SKI/Ub-SKIL [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SMURF2 monoubiquitinates SMAD3 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Xenopus tropicalis)
Degradation of Ub-SMAD7 (Xenopus tropicalis)
Ub-SMAD7 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Transcriptional regulation by RUNX2 (Xenopus tropicalis)
Regulation of RUNX2 expression and activity (Xenopus tropicalis)
26S proteasome degrades PolyUb-RUNX2 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Transcriptional regulation by RUNX3 (Xenopus tropicalis)
Regulation of RUNX3 expression and activity (Xenopus tropicalis)
MDM2 polyubiquitinates RUNX3 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SMURFs ubiquitinate RUNX3 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Deubiquitination (Xenopus tropicalis)
Metalloprotease DUBs (Xenopus tropicalis)
MYSM1 deubiquitinates Histone H2A (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
UCH proteinases (Xenopus tropicalis)
Histone H2A is dubiquitinated by the PR-DUB complex (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub-specific processing proteases (Xenopus tropicalis)
USP16,USP21 deubiquitinate Histone H2A (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
USP3,SAGA deubiquitinate Histone H2A,H2B (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
USP49 deubiquitinates H2B (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Protein ubiquitination (Xenopus tropicalis)
E3 ubiquitin ligases ubiquitinate target proteins (Xenopus tropicalis)
RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Xenopus tropicalis)
PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Xenopus tropicalis)
Ub:UBE2A,B [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:UBE2A,B [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
RNF20:RNF40 monoubiquitinates Histone H2B (Xenopus tropicalis)
PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Xenopus tropicalis)
Ub:UBE2A,B [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Xenopus tropicalis)
UBA1 adenylates ubiquitin in the nucleoplasm (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
UBA1 conjugates ubiquitin to UBA1 in the nucleus (Xenopus tropicalis)
Ub-Cys632-UBA1 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
UBA1 conjugates ubiquitin to nuclear E2 enzymes (Xenopus tropicalis)
Ub-Cys632-UBA1:ubiquitin adenylate [nucleoplasm] (Xenopus tropicalis)
Ub-Cys632-UBA1 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub:E2 (UBA1 substrate) [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub-Cys632-UBA1 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Ub-Cys632-UBA1:ubiquitin adenylate [nucleoplasm] (Xenopus tropicalis)
Ub-Cys632-UBA1 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
PTEN Regulation (Xenopus tropicalis)
Regulation of PTEN localization (Xenopus tropicalis)
USP7 deubiquitinates monoubiquitinated PTEN (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Signaling by Hedgehog (Xenopus tropicalis)
Hedgehog 'on' state (Xenopus tropicalis)
GLI2,3 are degraded by the proteasome (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Signaling by TGFB family members (Xenopus tropicalis)
Signaling by TGF-beta Receptor Complex (Xenopus tropicalis)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Xenopus tropicalis)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Xenopus tropicalis)
Degradation of SMAD2/3:SMAD4 complex (Xenopus tropicalis)
Ub-p-T-2S-SMAD2,3:SMAD4 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Degradation of ubiquitinated SKI/SKIL (Xenopus tropicalis)
Ub-SKI/Ub-SKIL [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SMURF2 monoubiquitinates SMAD3 (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Xenopus tropicalis)
Degradation of Ub-SMAD7 (Xenopus tropicalis)
Ub-SMAD7 [nucleoplasm] (Xenopus tropicalis)
Ub [nucleoplasm] (Xenopus tropicalis)
Participants
members
rps27a [nucleoplasm]
(Xenopus tropicalis)
ubc [nucleoplasm]
(Xenopus tropicalis)
uba52 [nucleoplasm]
(Xenopus tropicalis)
Participates
as a component of
Ub:E2 (UBA1 substrate) [nucleoplasm] (Xenopus tropicalis)
Ub-Cys632-UBA1 [nucleoplasm] (Xenopus tropicalis)
Ub:UBE2A,B [nucleoplasm] (Xenopus tropicalis)
MonoUb:K15,K24-KIAA0101 [nucleoplasm] (Xenopus tropicalis)
MonoUb:K164-PCNA [nucleoplasm] (Xenopus tropicalis)
Ub-SKI/Ub-SKIL [nucleoplasm] (Xenopus tropicalis)
Ub-SMAD7 [nucleoplasm] (Xenopus tropicalis)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Xenopus tropicalis)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Xenopus tropicalis)
Ub-p-T-2S-SMAD2,3:SMAD4 [nucleoplasm] (Xenopus tropicalis)
Ub-EHMT1 [nucleoplasm] (Xenopus tropicalis)
Ub-EHMT2 [nucleoplasm] (Xenopus tropicalis)
UBE2D1,2,3:Ubiquitin [nucleoplasm] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha [nucleoplasm] (Xenopus tropicalis)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Xenopus tropicalis)
Ub:ERCC6 [nucleoplasm] (Xenopus tropicalis)
Ub,SUMO:XPC [nucleoplasm] (Xenopus tropicalis)
Ub:XPC [nucleoplasm] (Xenopus tropicalis)
MonoUb:K523,p-4S-FANCI [nucleoplasm] (Xenopus tropicalis)
MonoUb:K561,p-T691,S717-FANCD2 [nucleoplasm] (Xenopus tropicalis)
MonoUb:K682,K686,K694,K709-POLH [nucleoplasm] (Xenopus tropicalis)
as an input of
Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Xenopus tropicalis)
UBA1 adenylates ubiquitin in the nucleoplasm (Xenopus tropicalis)
KIAA0101 double monoubiquitination (Xenopus tropicalis)
RCHY1 monoubiquitinates POLH (Xenopus tropicalis)
SMURF2 monoubiquitinates SMAD3 (Xenopus tropicalis)
APC/C:Cdh1 polyubiquitinates SKP2 (Xenopus tropicalis)
Multiubiquitination of APC/C-associated Cdh1 (Xenopus tropicalis)
Ubiquitination of phosphorylated CDC25A (Xenopus tropicalis)
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Xenopus tropicalis)
Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Xenopus tropicalis)
MDM2 homodimers auto-ubiquitinate (Xenopus tropicalis)
RNF34 or RFFL ubiquitinates phosphorylated TP53 (Xenopus tropicalis)
MDM2 ubiquitinates DYRK2 (Xenopus tropicalis)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Xenopus tropicalis)
UV-DDB ubiquitinates XPC (Xenopus tropicalis)
SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Xenopus tropicalis)
MDM2 polyubiquitinates RUNX3 (Xenopus tropicalis)
SMURFs ubiquitinate RUNX3 (Xenopus tropicalis)
NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Xenopus tropicalis)
as an output of
USP16,USP21 deubiquitinate Histone H2A (Xenopus tropicalis)
USP3,SAGA deubiquitinate Histone H2A,H2B (Xenopus tropicalis)
USP49 deubiquitinates H2B (Xenopus tropicalis)
MYSM1 deubiquitinates Histone H2A (Xenopus tropicalis)
Histone H2A is dubiquitinated by the PR-DUB complex (Xenopus tropicalis)
Degradation of multiubiquitinated Cdh1 (Xenopus tropicalis)
APC/C:Cdh1-mediated degradation of Skp2 (Xenopus tropicalis)
Proteolytic degradation of ubiquitinated-Cdc25A (Xenopus tropicalis)
Ubiquitinated geminin is degraded by the proteasome (Xenopus tropicalis)
USP7 deubiquitinates monoubiquitinated PTEN (Xenopus tropicalis)
26S proteasome degrades PolyUb-RUNX2 (Xenopus tropicalis)
USP7 deubiquitinates MDM2 (Xenopus tropicalis)
USP7 deubiquitinates TP53 and counteracts MDM2 (Xenopus tropicalis)
UVSSA:USP7 deubiquitinates ERCC6 (Xenopus tropicalis)
GLI2,3 are degraded by the proteasome (Xenopus tropicalis)
Ub,pS335,S338,T NFE2L2 is degraded (Xenopus tropicalis)
Inferred From
Ub [nucleoplasm]
(Homo sapiens)
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