PCNA homotrimer

Summation

This complex/polymer has been computationally inferred (based on Ensembl Compara) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

• 3 x PCNA [nucleoplasm] (Xenopus tropicalis)

Participant Of

hasMember

• PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm]

input

• GADD45A binds PCNA
• Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere
• Loading of PCNA - Sliding Clamp Formation
• MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA

output

• Disassociation of Processive Complex and Completed Telomere End

hasComponent

• EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm]
• GADD45A:PCNA [nucleoplasm]
• MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm]
• MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm]
• PCNA:POLD,POLE [nucleoplasm]
• PCNA:POLD,POLE:RPA:RFC [nucleoplasm]
• PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm]
• PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
• Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm]
• Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm]
• Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm]
• Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm]
• Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm]
• RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm]
• RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm]
• RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm]
• RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm]

Inferred From

PCNA homotrimer [nucleoplasm] (Homo sapiens)