Reactome | ints12 [nucleoplasm]

ints12 [nucleoplasm]

Stable Identifier

R-XTR-6807456

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

INTS12, Q0V9U1

Locations in the PathwayBrowser

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Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - RNA polymerase II transcribes snRNA genes (Xenopus tropicalis)
    - Integrator complex processes the 3' end of snRNA (Xenopus tropicalis)
      - Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints12 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints12 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints12 [nucleoplasm] (Xenopus tropicalis)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints12 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        Integrator [nucleoplasm] (Xenopus tropicalis)
        
        ints12 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q0V9U1

Gene Names

ints12

Reference Genes

BioGPS Gene:779778 ints12

ENSEMBL:ENSXETG00000014107

KEGG Gene (Xenopus tropicalis):779778 ints12

Monarch:779778 ints12

NCBI Gene:779778 ints12

Reference Transcript

RefSeq:NM_001078857.1 ints12

Participates

as a component of

Integrator [nucleoplasm] (Xenopus tropicalis)

Inferred From

INTS12 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001072325.1

Xenbase

XB-GENE-977203

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