Reactome | ice2 [nucleoplasm]

ice2 [nucleoplasm]

Stable Identifier

R-XTR-6807421

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

ICE2, F6VKW5

Locations in the PathwayBrowser

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Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - RNA polymerase II transcribes snRNA genes (Xenopus tropicalis)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        LEC [nucleoplasm] (Xenopus tropicalis)
        
        ice2 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        LEC [nucleoplasm] (Xenopus tropicalis)
        
        ice2 [nucleoplasm] (Xenopus tropicalis)
    - Integrator complex processes the 3' end of snRNA (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        LEC [nucleoplasm] (Xenopus tropicalis)
        
        ice2 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        LEC [nucleoplasm] (Xenopus tropicalis)
        
        ice2 [nucleoplasm] (Xenopus tropicalis)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        LEC [nucleoplasm] (Xenopus tropicalis)
        
        ice2 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        LEC [nucleoplasm] (Xenopus tropicalis)
        
        ice2 [nucleoplasm] (Xenopus tropicalis)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Xenopus tropicalis)
      - LEC [nucleoplasm] (Xenopus tropicalis)
        
        ice2 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Xenopus tropicalis)
        
        LEC [nucleoplasm] (Xenopus tropicalis)
        
        ice2 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6VKW5

Gene Names

ice2

Reference Genes

ENSEMBL:ENSXETG00000004572 ice2

ENSEMBL:ENSXETG00000021120

Other Identifiers

100380136

GO:0000166

GO:0003674

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005743

GO:0006810

GO:0006879

GO:0008023

GO:0008150

GO:0009058

GO:0016020

GO:0016021

GO:0016887

GO:0022857

GO:0032991

GO:0034641

GO:0042592

GO:0042626

GO:0042795

GO:0042796

GO:0043167

GO:0043226

GO:0045945

GO:0055085

Str.26888.1.S1_at

StrEns.5700.1.S1_s_at

Participant Of

hasComponent

LEC [nucleoplasm]

Inferred From

ICE2 [nucleoplasm] (Homo sapiens)

Cross References

Ensembl

ENSXETT00000045664, ENSXETP00000045664, ENSXETG00000021120

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