Reactome | phospho-ifnlr1 [plasma membrane]

phospho-ifnlr1 [plasma membrane]

Stable Identifier

R-XTR-6784793-3

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

p-Y496-IL10RA, D2DJQ1

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Cytokine Signaling in Immune system (Xenopus tropicalis)
  - Signaling by Interleukins (Xenopus tropicalis)
    - Interleukin-10 signaling (Xenopus tropicalis)
      - IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        phospho-ifnlr1 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        phospho-ifnlr1 [plasma membrane] (Xenopus tropicalis)
      - STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        phospho-ifnlr1 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        phospho-ifnlr1 [plasma membrane] (Xenopus tropicalis)
      - p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        phospho-ifnlr1 [plasma membrane] (Xenopus tropicalis)
      - p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        phospho-ifnlr1 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Xenopus tropicalis)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Xenopus tropicalis)
        
        phospho-ifnlr1 [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:D2DJQ1

Gene Names

ifnlr1

Reference Genes

BioGPS Gene:100329166 ifnlr1

ENSEMBL:ENSXETG00000031947

KEGG Gene (Xenopus tropicalis):100329166 ifnlr1

Monarch:100329166 ifnlr1

NCBI Gene:100329166 ifnlr1

Reference Transcript

RefSeq:NM_001171767.1 ifnlr1

Other Identifiers

100329166

GO:0005515

GO:0016020

Participates

as a member of

Homologues of p-Y496-IL10RA [plasma membrane] (Xenopus tropicalis)

Other forms of this molecule

phospho-ifnlr1 [plasma membrane]

ifnlr1 [extracellular region]

ifnlr1 [plasma membrane]

phospho-ifnlr1 [plasma membrane]

ifnlr1 [plasma membrane]

phospho-ifnlr1 [plasma membrane]

ifnlr1 [plasma membrane]

Inferred From

p-Y496-IL10RA [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 496 (in Homo sapiens)

Coordinate

496

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001165238.1

Xenbase

XB-GENE-6462098

Ensembl

ENSXETT00000066441, ENSXETG00000031947, ENSXETP00000060093

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