Reactome | thbs1 [extracellular region]

thbs1 [extracellular region]

Stable Identifier

R-XTR-66518

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

extracellular region

Synonyms

THBS1, F6XC33

Locations in the PathwayBrowser

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Hemostasis (Xenopus tropicalis)

- Platelet activation, signaling and aggregation (Xenopus tropicalis)
  - Response to elevated platelet cytosolic Ca2+ (Xenopus tropicalis)
    - Platelet degranulation (Xenopus tropicalis)
      - Exocytosis of platelet alpha granule contents (Xenopus tropicalis)
        
        Platelet alpha granule contents [extracellular region] (Xenopus tropicalis)
        
        THBS1 trimer [extracellular region] (Xenopus tropicalis)
        
        thbs1 [extracellular region] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
  - Signaling by PDGF (Xenopus tropicalis)
    - PDGF binds to extracellular matrix proteins (Xenopus tropicalis)
      - Extracellular matrix ligands [extracellular region] (Xenopus tropicalis)
        
        Thrombospondin [extracellular region] (Xenopus tropicalis)
        
        thbs1 [extracellular region] (Xenopus tropicalis)
      - PDGF A and B chains:ECM complex [extracellular region] (Xenopus tropicalis)
        
        Extracellular matrix ligands [extracellular region] (Xenopus tropicalis)
        
        Thrombospondin [extracellular region] (Xenopus tropicalis)
        
        thbs1 [extracellular region] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6XC33

Gene Names

thbs1

Reference Genes

BioGPS Gene:100170153 thbs1

ENSEMBL:ENSXETG00000011217

KEGG Gene (Xenopus tropicalis):100170153 thbs1

Monarch:100170153 thbs1

NCBI Gene:100170153 thbs1

Reference Transcript

RefSeq:XM_002937199.3 thbs1

Other Identifiers

100170153

GO:0005509

GO:0005515

GO:0005576

GO:0005615

GO:0007155

GO:0008201

GO:0016525

GO:0030312

GO:0031012

GO:0048856

GO:0050840

GO:0062023

Participates

as a member of

Thrombospondin [extracellular region] (Xenopus tropicalis)

as a component of

THBS1 trimer [extracellular region] (Xenopus tropicalis)

Other forms of this molecule

thbs1 [endoplasmic reticulum lumen]

thbs1 [platelet alpha granule lumen]

Inferred From

THBS1 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_002937245.1

Ensembl

ENSXETG00000011217, ENSXETP00000024496, ENSXETT00000024496

Xenbase

XB-GENE-486189

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