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Factor V precursor [endoplasmic reticulum lumen]
Stable Identifier
R-XTR-5689447
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
endoplasmic reticulum lumen
Synonyms
K9J7M8
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Asparagine N-linked glycosylation (Xenopus tropicalis)
Transport to the Golgi and subsequent modification (Xenopus tropicalis)
ER to Golgi Anterograde Transport (Xenopus tropicalis)
COPII-mediated vesicle transport (Xenopus tropicalis)
Inner coat assembly and cargo binding (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Loss of SAR1B GTPase (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
SEC31:SEC13 and v-SNARE recruitment (Xenopus tropicalis)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Cargo concentration in the ER (Xenopus tropicalis)
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Inner coat assembly and cargo binding (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Post-translational protein phosphorylation (Xenopus tropicalis)
FAM20C phosphorylates FAM20C substrates (Xenopus tropicalis)
FAM20C:FAM20C substrates [endoplasmic reticulum lumen] (Xenopus tropicalis)
FAM20C substrates [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Xenopus tropicalis)
FAM20C phosphorylates FAM20C substrates (Xenopus tropicalis)
FAM20C:FAM20C substrates [endoplasmic reticulum lumen] (Xenopus tropicalis)
FAM20C substrates [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Vesicle-mediated transport (Xenopus tropicalis)
Membrane Trafficking (Xenopus tropicalis)
ER to Golgi Anterograde Transport (Xenopus tropicalis)
COPII-mediated vesicle transport (Xenopus tropicalis)
Inner coat assembly and cargo binding (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Loss of SAR1B GTPase (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
SEC31:SEC13 and v-SNARE recruitment (Xenopus tropicalis)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Cargo concentration in the ER (Xenopus tropicalis)
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Inner coat assembly and cargo binding (Xenopus tropicalis)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
COPII cargo:receptors [endoplasmic reticulum membrane] (Xenopus tropicalis)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Xenopus tropicalis)
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
Factor V precursor [endoplasmic reticulum lumen] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:K9J7M8
Reference Genes
ENSEMBL:ENSXETG00000002423
Other Identifiers
AAMC01049956
AAMC01049957
AAMC01049958
AAMC01049959
ENSXETG00000002423
ENSXETP00000005164
ENSXETT00000005164
f5-201
GO:0003674
GO:0005507
GO:0009617
GO:0016491
GO:0043167
GO:0046872
GO:0055114
IPR000421
IPR008972
IPR008979
IPR011706
IPR011707
IPR024715
IPR033138
PF00754
PF07731
PF07732
SM00231
StrEns.4058.1.S1_at
StrJgi.2333.1.S1_at
UPI00020660EA
XB-GENE-987398
Participant Of
hasMember
FAM20C substrates [endoplasmic reticulum lumen]
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen]
Other forms of this molecule
F5(535-737) [extracellular region]
F5(335-534) [extracellular region]
F5(29-334) [extracellular region]
F5(29-534) [extracellular region]
factor V [platelet alpha granule lumen]
phospho-p-Factor V precursor [endoplasmic reticulum lumen]
Factor V precursor [endoplasmic reticulum-Golgi intermediate compartment membrane]
Factor V precursor [COPII-coated ER to Golgi transport vesicle]
factor V activation peptide [extracellular region]
factor V [extracellular region]
factor Va heavy chain [extracellular region]
factor Va light chain [extracellular region]
factor Va heavy chain [plasma membrane]
factor Va light chain [plasma membrane]
Inferred From
Factor V precursor [endoplasmic reticulum lumen] (Homo sapiens)
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