Reactome | elmo2 [plasma membrane]

elmo2 [plasma membrane]

Stable Identifier

R-XTR-5633393

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

TNFRSF10A, F6WAR4

Locations in the PathwayBrowser

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Programmed Cell Death (Xenopus tropicalis)

- Apoptosis (Xenopus tropicalis)
  - Caspase activation via extrinsic apoptotic signalling pathway (Xenopus tropicalis)
    - Caspase activation via Death Receptors in the presence of ligand (Xenopus tropicalis)
      - Dimerization of procaspase-8 (Xenopus tropicalis)
        
        TRAIL-mediated dimerization of procaspase-8 (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD:2xCASP8(1-479) [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
      - Regulation by c-FLIP (Xenopus tropicalis)
        
        Caspase-8 and FLIP(L) processing at DISC (Xenopus tropicalis)
        
        DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Xenopus tropicalis)
        
        DISC [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
        
        DISC:procaspase-8:FLIP(L) [plasma membrane] (Xenopus tropicalis)
        
        DISC:procaspase-8 [plasma membrane] (Xenopus tropicalis)
        
        DISC [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
        
        FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
- Regulated Necrosis (Xenopus tropicalis)
  - RIPK1-mediated regulated necrosis (Xenopus tropicalis)
    - Regulation of necroptotic cell death (Xenopus tropicalis)
      - CASP8 activity is inhibited (Xenopus tropicalis)
        
        FLIP(L) and procaspase-8 form heterodimer (Xenopus tropicalis)
        
        DISC:procaspase-8 [plasma membrane] (Xenopus tropicalis)
        
        DISC [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
        
        DISC:procaspase-8:FLIP(L) [plasma membrane] (Xenopus tropicalis)
        
        DISC:procaspase-8 [plasma membrane] (Xenopus tropicalis)
        
        DISC [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
        
        FLIP(S) and procaspase-8 form heterodimer (Xenopus tropicalis)
        
        DISC:procaspase-8 [plasma membrane] (Xenopus tropicalis)
        
        DISC [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)
        
        DISC:procaspase-8:FLIP(S) [plasma membrane] (Xenopus tropicalis)
        
        DISC:procaspase-8 [plasma membrane] (Xenopus tropicalis)
        
        DISC [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Xenopus tropicalis)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Xenopus tropicalis)
        
        elmo2 [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6WAR4

Gene Names

elmo2

Reference Genes

ENSEMBL:ENSXETG00000007361 elmo2

ENSEMBL:ENSXETG00000010510

Other Identifiers

448240

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005886

GO:0006810

GO:0006909

GO:0006915

GO:0007010

GO:0007015

GO:0007155

GO:0007165

GO:0008150

GO:0008219

GO:0009986

GO:0016192

GO:0016477

GO:0017124

GO:0019899

GO:0036462

GO:0040011

GO:0043065

GO:0048365

GO:0048870

GO:0098609

Str.7168.1.S1_at

Participant Of

input

hasComponent

Other forms of this molecule

elmo2 [plasma membrane]

Inferred From

TNFRSF10A [plasma membrane] (Homo sapiens)

TNFRSF10A,TNFRSF10B [plasma membrane] (Homo sapiens)

Cross References

Ensembl

ENSXETG00000010510, ENSXETT00000023053, ENSXETP00000023053

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