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H2AFX [nucleoplasm]
Stable Identifier
R-XTR-56151
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
nucleoplasm
Synonyms
A0A6I8QK78
Locations in the PathwayBrowser
Expand all
Cell Cycle (Xenopus tropicalis)
Cell Cycle, Mitotic (Xenopus tropicalis)
M Phase (Xenopus tropicalis)
Mitotic Prophase (Xenopus tropicalis)
Condensation of Prophase Chromosomes (Xenopus tropicalis)
PHF8 demethylates histone H4K20me1 (Xenopus tropicalis)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2/3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
SETD8 monomethylates histone H4 (Xenopus tropicalis)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2/3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
Cellular responses to external stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular Senescence (Xenopus tropicalis)
Oxidative Stress Induced Senescence (Xenopus tropicalis)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Xenopus tropicalis)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K27me3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
CDKN2A Gene:Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
DNA Repair (Xenopus tropicalis)
Base Excision Repair (Xenopus tropicalis)
Base-Excision Repair, AP Site Formation (Xenopus tropicalis)
Depurination (Xenopus tropicalis)
Cleavage of the damaged purine (Xenopus tropicalis)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Xenopus tropicalis)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Xenopus tropicalis)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Xenopus tropicalis)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
Recognition and association of DNA glycosylase with site containing an affected purine (Xenopus tropicalis)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Xenopus tropicalis)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Xenopus tropicalis)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
Gene expression (Transcription) (Xenopus tropicalis)
Epigenetic regulation of gene expression (Xenopus tropicalis)
PRC2 methylates histones and DNA (Xenopus tropicalis)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Xenopus tropicalis)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Xenopus tropicalis)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Xenopus tropicalis)
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K27me3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Xenopus tropicalis)
PRC2 Core:Chromatin [nucleoplasm] (Xenopus tropicalis)
Chromatin [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PRC2 trimethylates histone H3 at lysine-27 (Xenopus tropicalis)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Xenopus tropicalis)
Chromatin with trimethylated H3K27 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K27me3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PRC2:Chromatin [nucleoplasm] (Xenopus tropicalis)
Chromatin [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Xenopus tropicalis)
Chromatin [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PRC2:Chromatin [nucleoplasm] (Xenopus tropicalis)
Chromatin [nucleoplasm] (Xenopus tropicalis)
Nucleosome [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional regulation by RUNX1 (Xenopus tropicalis)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Xenopus tropicalis)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase Effectors (Xenopus tropicalis)
RHO GTPases activate PKNs (Xenopus tropicalis)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Xenopus tropicalis)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Xenopus tropicalis)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Xenopus tropicalis)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Xenopus tropicalis)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Xenopus tropicalis)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Xenopus tropicalis)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K9me3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Xenopus tropicalis)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Xenopus tropicalis)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K9me3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Xenopus tropicalis)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Xenopus tropicalis)
Nucleosome with H3K9me3 [nucleoplasm] (Xenopus tropicalis)
Histone H2A [nucleoplasm] (Xenopus tropicalis)
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
H2AFX [nucleoplasm] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A6I8QK78
Reference Genes
ENSEMBL:ENSXETG00000037940
Participates
as a member of
Homologues of H2AFX [nucleoplasm] (Xenopus tropicalis)
Other forms of this molecule
Ub-HIST2H2AB [nucleoplasm]
AcK6-HIST2H2AB [nucleoplasm]
AcK-HIST2H2AB [nucleoplasm]
Me2aR30-HIST2H2AB [nucleoplasm]
MeR30-HIST2H2AB [nucleoplasm]
Me2aR4-HIST2H2AB [nucleoplasm]
MeR4-HIST2H2AB [nucleoplasm]
Me2sR4-H2AFB1 [nucleoplasm]
Me2sR4-H2AFX [nucleoplasm]
Me2aR12-HIST2H2AB [nucleoplasm]
MeR12-HIST2H2AB [nucleoplasm]
HIST2H2AB [nucleoplasm]
H2AFB1 [nucleoplasm]
phospho-p-Y143-H2AFX [nucleoplasm]
Inferred From
H2AFX [nucleoplasm]
(Homo sapiens)
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