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XIAP [cytosol]
Stable Identifier
R-XTR-50849
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
Q5BKL8
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Xenopus tropicalis)
Apoptosis (Xenopus tropicalis)
Intrinsic Pathway for Apoptosis (Xenopus tropicalis)
Apoptotic factor-mediated response (Xenopus tropicalis)
Cytochrome c-mediated apoptotic response (Xenopus tropicalis)
Activation of caspases through apoptosome-mediated cleavage (Xenopus tropicalis)
Cleavage of Procaspase-3 by the apoptosome (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
Cleavage of Procaspase-7 by the apoptosome (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
Formation of apoptosome (Xenopus tropicalis)
Regulation of the apoptosome activity (Xenopus tropicalis)
XIAP binds CASP9 (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
XIAP:apoptosome [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
SMAC, XIAP-regulated apoptotic response (Xenopus tropicalis)
SMAC (DIABLO) binds to IAPs (Xenopus tropicalis)
SMAC (DIABLO) binds XIAP (Xenopus tropicalis)
DIABLO dimer:XIAP [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
SMAC binds XIAP:Caspase-7 (Xenopus tropicalis)
DIABLO:XIAP:Caspase-7 [cytosol] (Xenopus tropicalis)
XIAP:Caspase-7 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
XIAP:Caspase-7 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes (Xenopus tropicalis)
Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Xenopus tropicalis)
DIABLO dimer:XIAP [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
DIABLO:XIAP:Caspase-7 [cytosol] (Xenopus tropicalis)
XIAP:Caspase-7 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
XIAP binds CASP3 (Xenopus tropicalis)
DIABLO:XIAP:Caspase-3 [cytosol] (Xenopus tropicalis)
XIAP:Caspase-3 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
XIAP:Caspase-3 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
XIAP binds CASP7 (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
XIAP:Caspase-7 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
Regulated Necrosis (Xenopus tropicalis)
RIPK1-mediated regulated necrosis (Xenopus tropicalis)
Regulation of necroptotic cell death (Xenopus tropicalis)
BIRC2/3 (cIAP1/2) is autoubiquitinated (Xenopus tropicalis)
BIRC2,3,4 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
TNF signaling (Xenopus tropicalis)
TNFR1-induced NF-kappa-B signaling pathway (Xenopus tropicalis)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Xenopus tropicalis)
BIRC2,3,4 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Xenopus tropicalis)
BIRC2,3,4 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Xenopus tropicalis)
BIRC2,3,4 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Xenopus tropicalis)
BIRC2,3,4 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Xenopus tropicalis)
BIRC2,3,4 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
PTEN Regulation (Xenopus tropicalis)
Regulation of PTEN localization (Xenopus tropicalis)
PTEN undergoes monoubiquitination (Xenopus tropicalis)
XIAP,NEDD4 [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
Regulation of PTEN stability and activity (Xenopus tropicalis)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Xenopus tropicalis)
NEDD4,STUB1,WWP2 and XIAP [cytosol] (Xenopus tropicalis)
XIAP [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q5BKL8
Reference Genes
BioGPS Gene:594971
ENSEMBL:ENSXETG00000016194
KEGG Gene (Xenopus tropicalis):594971
Monarch:594971
NCBI Gene:594971
Reference Transcript
RefSeq:NM_001030412.1
Participates
as a member of
NEDD4,STUB1,WWP2 and XIAP [cytosol] (Xenopus tropicalis)
as a candidate of
XIAP,NEDD4 [cytosol] (Xenopus tropicalis)
BIRC2,3,4 [cytosol] (Xenopus tropicalis)
as an input of
SMAC (DIABLO) binds XIAP (Xenopus tropicalis)
XIAP binds CASP3 (Xenopus tropicalis)
XIAP binds CASP7 (Xenopus tropicalis)
XIAP binds CASP9 (Xenopus tropicalis)
as a component of
XIAP:apoptosome [cytosol] (Xenopus tropicalis)
XIAP:Caspase-7 [cytosol] (Xenopus tropicalis)
DIABLO dimer:XIAP [cytosol] (Xenopus tropicalis)
XIAP:Caspase-3 [cytosol] (Xenopus tropicalis)
This entity regulates
Negatively
Cleavage of Procaspase-7 by the apoptosome
(Xenopus tropicalis)
Cleavage of Procaspase-3 by the apoptosome
(Xenopus tropicalis)
Other forms of this molecule
XIAP [nucleoplasm]
K48pUb-XIAP [cytosol]
Inferred From
XIAP [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001025583.1
Xenbase
XB-GENE-948846
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