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apaf1 [cytosol]
Stable Identifier
R-XTR-50099
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
APAF1, F7B7S7
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Xenopus tropicalis)
Apoptosis (Xenopus tropicalis)
Intrinsic Pathway for Apoptosis (Xenopus tropicalis)
Apoptotic factor-mediated response (Xenopus tropicalis)
Cytochrome c-mediated apoptotic response (Xenopus tropicalis)
Activation of caspases through apoptosome-mediated cleavage (Xenopus tropicalis)
Cleavage of Procaspase-3 by the apoptosome (Xenopus tropicalis)
Apoptosome [cytosol] (Xenopus tropicalis)
APAF1:CYCS [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
Cleavage of Procaspase-7 by the apoptosome (Xenopus tropicalis)
Apoptosome [cytosol] (Xenopus tropicalis)
APAF1:CYCS [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
Formation of apoptosome (Xenopus tropicalis)
CYCS binds to APAF1 (Xenopus tropicalis)
APAF1:ADP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
CYCS:APAF1 binds procaspase-9 (Xenopus tropicalis)
APAF1:ATP:CYCS [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
Cleavage of Procaspase‑9 to caspase‑9 (Xenopus tropicalis)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Xenopus tropicalis)
APAF1:CYCS [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
Apoptosome [cytosol] (Xenopus tropicalis)
APAF1:CYCS [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
Procaspase 9 forms dimer (Xenopus tropicalis)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Xenopus tropicalis)
APAF1:CYCS [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
Regulation of the apoptosome activity (Xenopus tropicalis)
APAF1 binds AVEN (Xenopus tropicalis)
APAF1:ADP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
APAF1:AVEN [cytosol] (Xenopus tropicalis)
APAF1:ADP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
APAF1:CYCS binds APIP (Xenopus tropicalis)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
APAF1:CYCS:ATP:APIP [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
CASP9 is phosphorylated at T412 (Xenopus tropicalis)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Xenopus tropicalis)
APAF1:ATP:CYCS [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
XIAP binds CASP9 (Xenopus tropicalis)
Apoptosome [cytosol] (Xenopus tropicalis)
APAF1:CYCS [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
XIAP:apoptosome [cytosol] (Xenopus tropicalis)
Apoptosome [cytosol] (Xenopus tropicalis)
APAF1:CYCS [cytosol] (Xenopus tropicalis)
apaf1 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F7B7S7
Gene Names
apaf1
Reference Genes
ENSEMBL:ENSXETG00000006695
KEGG Gene (Xenopus tropicalis):100127738 apaf1
Reference Transcript
RefSeq:XM_012959843.3 apaf1
RefSeq:XM_031898854.1 apaf1
Other Identifiers
100127738
GO:0000166
GO:0003824
GO:0005524
GO:0005737
GO:0005829
GO:0006508
GO:0006915
GO:0008233
GO:0012501
GO:0016787
GO:0023052
GO:0042981
GO:0043293
GO:0043531
GO:0097190
GO:0140096
Participates
as a component of
APAF1:ADP [cytosol] (Xenopus tropicalis)
APAF1:ATP [cytosol] (Xenopus tropicalis)
APAF1:CYCS [cytosol] (Xenopus tropicalis)
Other forms of this molecule
apaf1 [secretory granule lumen]
apaf1 [extracellular region]
apaf1 [ficolin-1-rich granule lumen]
Inferred From
APAF1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_031754714.1
,
XP_012815297.2
Ensembl
ENSXETG00000006695
,
ENSXETT00000014654
,
ENSXETP00000014654
Xenbase
XB-GENE-988968
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