Reactome | atf2 [nucleoplasm]

atf2 [nucleoplasm]

Stable Identifier

R-XTR-450336

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

ATF2, A0A6I8QVI2

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Cytokine Signaling in Immune system (Xenopus tropicalis)
  - Signaling by Interleukins (Xenopus tropicalis)
    - Interleukin-17 signaling (Xenopus tropicalis)
      - MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
- Innate Immune System (Xenopus tropicalis)
  - Toll-like Receptor Cascades (Xenopus tropicalis)
    - Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
      - MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
      - Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
      - Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
      - MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
      - MyD88-independent TLR4 cascade (Xenopus tropicalis)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
      - MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
      - MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
      - MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)
        
        atf2 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A6I8QVI2

Gene Names

atf2

Reference Genes

ENSEMBL:ENSXETG00000015003

Reference Transcript

Other Identifiers

100038142

100485532

GO:0003677

GO:0003700

GO:0005634

GO:0006351

GO:0006355

GO:0043226

GO:0140110

Participates

as an input of

Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)

Other forms of this molecule

phospho-atf2 [nucleoplasm]

Inferred From

ATF2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_017953047.2, XP_017953048.2, XP_017953049.2

Ensembl

ENSXETP00000073620, ENSXETT00000083624, ENSXETG00000015003

Xenbase

XB-GENE-961088

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