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esr1 [nucleoplasm]
Stable Identifier
R-XTR-446168
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
nucleoplasm
Synonyms
ESR1, Q6W5G9
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Nuclear Receptor transcription pathway (Xenopus tropicalis)
Formation of NR-MED1 Coactivator Complex (Xenopus tropicalis)
NR [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
NR-MED1 Coactivator Complex [nucleoplasm] (Xenopus tropicalis)
NR [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
Formation of NR-NCOR Corepressor Complex (Xenopus tropicalis)
NR [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
NR-NCOR CoRepressor Complex [nucleoplasm] (Xenopus tropicalis)
NR [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Xenopus tropicalis)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors (Xenopus tropicalis)
ATAD2 binds ESR1 (Xenopus tropicalis)
ATAD2:ESR1 [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Deubiquitination (Xenopus tropicalis)
Ovarian tumor domain proteases (Xenopus tropicalis)
OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Xenopus tropicalis)
OTUB1,(OTUB2):UBE2D1,ESR1 [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
SUMOylation (Xenopus tropicalis)
SUMO E3 ligases SUMOylate target proteins (Xenopus tropicalis)
SUMOylation of intracellular receptors (Xenopus tropicalis)
PIAS1,3 SUMOylate ESR1 with SUMO1 (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
ESR-mediated signaling (Xenopus tropicalis)
27-hydroxysterol binds ESR1, ESR2 (Xenopus tropicalis)
27-OH-CHOL:ESR1,2 [nucleoplasm] (Xenopus tropicalis)
ESR1,2 [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1,2 [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR dimerizes (Xenopus tropicalis)
ESR multimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:ESR2:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1:ESR2 [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1 binds ESR1 agonists (Xenopus tropicalis)
ESR1:ESR1 agonists [nucleoplasm] (Xenopus tropicalis)
ESR1:chaperone complex [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:chaperone complex [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1 binds ESR1 antagonists (Xenopus tropicalis)
ESR1:ESR1 antagonists [nucleoplasm] (Xenopus tropicalis)
ESR1:chaperone complex [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:chaperone complex [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESTG binds ESR1:chaperone complex (Xenopus tropicalis)
ESR1:chaperone complex [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESTG:ESR1:chaperone complex [nucleoplasm] (Xenopus tropicalis)
ESR1:chaperone complex [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
Estrogen-dependent gene expression (Xenopus tropicalis)
EP300 is recruited to MYC and BCL2 genes (Xenopus tropicalis)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300 [nucleoplasm] (Xenopus tropicalis)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ERBB4s80 forms a complex with estrogen receptor ESR1 (Xenopus tropicalis)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
HATs and coactivators are recruited to the CTSD gene (Xenopus tropicalis)
CTSD gene:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
CTSD gene:ESR1:ESTG:SP1:USF1:USF2:NCOA:EP300:MED1 [nucleoplasm] (Xenopus tropicalis)
CTSD gene:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
Histone acetyltransferases are recruited to the TFF1 gene (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1 [nucleoplasm] (Xenopus tropicalis)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1 [nucleoplasm] (Xenopus tropicalis)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Xenopus tropicalis)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Xenopus tropicalis)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
KDM1A is recruited to MYC and BCL2 genes (Xenopus tropicalis)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Xenopus tropicalis)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Xenopus tropicalis)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
NCOA3 binds ESR1:estrogen:TFGA gene (Xenopus tropicalis)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 (Xenopus tropicalis)
ESR1:estrogen:ERE:NCOA3:EP300 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1:estrogen:ERE:NCOA3:TFGA gene [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen:TGFA gene promoter [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Xenopus tropicalis)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] (Xenopus tropicalis)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Xenopus tropicalis)
MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Xenopus tropicalis)
ESR1:ESTG:P-TEFb [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Xenopus tropicalis)
ESR1:ESTG:P-TEFb [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by ERBB4 (Xenopus tropicalis)
Nuclear signaling by ERBB4 (Xenopus tropicalis)
ERBB4s80 forms a complex with estrogen receptor ESR1 (Xenopus tropicalis)
ERBB4s80:ESR1:estrogen [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
ESR1 dimer:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
esr1 [nucleoplasm] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q6W5G9
Gene Names
esr1
Reference Genes
BioGPS Gene:394461 esr1
ENSEMBL:ENSXETG00000012364
KEGG Gene (Xenopus tropicalis):394461 esr1
Monarch:394461 esr1
NCBI Gene:394461 esr1
Reference Transcript
RefSeq:NM_203535.1 esr1
Participates
as a component of
ESR1 dimer:estrogen [nucleoplasm] (Xenopus tropicalis)
OTUB1,(OTUB2):UBE2D1,ESR1 [nucleoplasm] (Xenopus tropicalis)
ATAD2:ESR1 [nucleoplasm] (Xenopus tropicalis)
ESR1:chaperone complex [nucleoplasm] (Xenopus tropicalis)
ESR1:ESR2 [nucleoplasm] (Xenopus tropicalis)
ESR1:ESTG [nucleoplasm] (Xenopus tropicalis)
ESR1 homodimer [nucleoplasm] (Xenopus tropicalis)
as a member of
ESR1,2 [nucleoplasm] (Xenopus tropicalis)
NR [nucleoplasm] (Xenopus tropicalis)
as an input of
OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Xenopus tropicalis)
PIAS1,3 SUMOylate ESR1 with SUMO1 (Xenopus tropicalis)
ATAD2 binds ESR1 (Xenopus tropicalis)
Other forms of this molecule
phospho-esr1 [nucleoplasm]
esr1 [nucleoplasm]
phospho-esr1 [nucleoplasm]
phospho-esr1 [cytosol]
esr1 [cytosol]
esr1 [cytosol]
esr1 [cytosol]
esr1 [plasma membrane]
esr1 [plasma membrane]
esr1 [plasma membrane]
esr1 [plasma membrane]
esr1 [cytosol]
Inferred From
UBE2D1,ESR1 [nucleoplasm]
(Homo sapiens)
ESR1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_988866.1
Xenbase
XB-GENE-482193
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