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arhgef7 [cytosol]
Stable Identifier
R-XTR-430346
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
ARHGEF7, A0A6I8RQF4
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
EPH-Ephrin signaling (Xenopus tropicalis)
Ephrin signaling (Xenopus tropicalis)
GIT1 binds bPIX (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
PAK binds RAC and bPIX (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
PAKs autophosphorylate (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
PAKs phosphorylate MLC (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
bPIX exchanges GTP for GDP on RAC, activating it (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
p75 NTR receptor-mediated signalling (Xenopus tropicalis)
Cell death signalling via NRAGE, NRIF and NADE (Xenopus tropicalis)
NRAGE signals death through JNK (Xenopus tropicalis)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Xenopus tropicalis)
GEFs [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (12/13) signalling events (Xenopus tropicalis)
GEFs activate RhoA,B,C (Xenopus tropicalis)
GEFs [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by EGFR (Xenopus tropicalis)
EGFR downregulation (Xenopus tropicalis)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Xenopus tropicalis)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Xenopus tropicalis)
Beta-Pix:CDC42:GTP [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase cycle (Xenopus tropicalis)
RAC1 GTPase cycle (Xenopus tropicalis)
RAC1 GEFs activate RAC1 (Xenopus tropicalis)
RAC1 GEFs [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
RHOA GTPase cycle (Xenopus tropicalis)
RHOA GEFs activate RHOA (Xenopus tropicalis)
RHOA GEFs [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
RHOQ GTPase cycle (Xenopus tropicalis)
RHOQ binds effectors at the plasma membrane (Xenopus tropicalis)
RHOQ effectors [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Xenopus tropicalis)
RHOQ effectors [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
RHOU GTPase cycle (Xenopus tropicalis)
RHOU binds effectors at the plasma membrane (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
RHOU:GTP:RHOU effectors [plasma membrane] (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
RHOV GTPase cycle (Xenopus tropicalis)
RHOV binds effectors at the plasma membrane (Xenopus tropicalis)
RHOV effectors [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
RHOV:GTP:RHOV effectors [plasma membrane] (Xenopus tropicalis)
RHOV effectors [cytosol] (Xenopus tropicalis)
arhgef7 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A6I8RQF4
Gene Names
arhgef7
Reference Genes
BioGPS Gene:100145259 arhgef7
ENSEMBL:ENSXETG00000008213
Monarch:100145259 arhgef7
NCBI Gene:100145259 arhgef7
Reference Transcript
RefSeq:XM_012957889.3 arhgef7
Other Identifiers
100145259
GO:0005085
GO:0023052
GO:0030027
GO:0035556
GO:0098772
Participates
as a candidate of
RHOA GEFs [cytosol] (Xenopus tropicalis)
RHOV effectors [cytosol] (Xenopus tropicalis)
RHOQ effectors [cytosol] (Xenopus tropicalis)
CDC42 effectors [cytosol] (Xenopus tropicalis)
RAC1 GEFs [cytosol] (Xenopus tropicalis)
RHOJ effectors [cytosol] (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
as an input of
GIT1 binds bPIX (Xenopus tropicalis)
as a component of
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Xenopus tropicalis)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Xenopus tropicalis)
Beta-Pix:CDC42:GTP [cytosol] (Xenopus tropicalis)
as a member of
GEFs [cytosol] (Xenopus tropicalis)
Inferred From
ARHGEF7 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_012813343.1
Ensembl
ENSXETG00000008213
,
ENSXETT00000068774
,
ENSXETP00000083567
Xenbase
XB-GENE-962606
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