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vav3 [cytosol]
Stable Identifier
R-XTR-430152
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
VAV3, F6USI5
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
EPH-Ephrin signaling (Xenopus tropicalis)
EPH-ephrin mediated repulsion of cells (Xenopus tropicalis)
SFKs phosphorylate VAV2,3 (Xenopus tropicalis)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
p-EPHs bind VAV2,3 (Xenopus tropicalis)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Hemostasis (Xenopus tropicalis)
Platelet activation, signaling and aggregation (Xenopus tropicalis)
GPVI-mediated activation cascade (Xenopus tropicalis)
VAV1 is a GEF for Rho/Rac family GTPases (Xenopus tropicalis)
PIP3:VAV1,2,3 [plasma membrane] (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
VAV family:PIP2 [plasma membrane] (Xenopus tropicalis)
VAV family [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
p-SLP-76 binds VAV (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
p-SLP-76:VAV [cytosol] (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
DAP12 interactions (Xenopus tropicalis)
DAP12 signaling (Xenopus tropicalis)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Recruitment of VAV and BTK to p-SLP-76 (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Release of p-PLCG1 (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV [plasma membrane] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
FCERI mediated Ca+2 mobilization (Xenopus tropicalis)
Autophosphorylation of BTK/ITK (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases [plasma membrane] (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Hydrolysis of PIP2 by PLCG (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3 [plasma membrane] (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
FCERI mediated MAPK activation (Xenopus tropicalis)
Phosphorylation and activation of VAV (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Recruitment of VAV to p-SLP-76 (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
p75 NTR receptor-mediated signalling (Xenopus tropicalis)
Cell death signalling via NRAGE, NRIF and NADE (Xenopus tropicalis)
NRAGE signals death through JNK (Xenopus tropicalis)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Xenopus tropicalis)
GEFs [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (12/13) signalling events (Xenopus tropicalis)
GEFs activate RhoA,B,C (Xenopus tropicalis)
GEFs [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
VAV exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)
VAV family [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase cycle (Xenopus tropicalis)
CDC42 GTPase cycle (Xenopus tropicalis)
CDC42 GEFs activate CDC42 (Xenopus tropicalis)
CDC42 GEFs [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
RAC1 GTPase cycle (Xenopus tropicalis)
RAC1 GEFs activate RAC1 (Xenopus tropicalis)
RAC1 GEFs [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
RAC2 GTPase cycle (Xenopus tropicalis)
RAC2 GEFs activate RAC2 (Xenopus tropicalis)
RAC2 GEFs [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
RHOA GTPase cycle (Xenopus tropicalis)
RHOA GEFs activate RHOA (Xenopus tropicalis)
RHOA GEFs [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
RHOG GTPase cycle (Xenopus tropicalis)
RHOG GEFs activate RHOG (Xenopus tropicalis)
RHOG GEFs [cytosol] (Xenopus tropicalis)
vav3 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F6USI5
Gene Names
vav3
Reference Genes
BioGPS Gene:100493918 vav3
ENSEMBL:ENSXETG00000009944
Monarch:100493918 vav3
NCBI Gene:100493918 vav3
UCSC:F6USI5 vav3
Reference Transcript
RefSeq:XM_012962510.3 vav3
Other Identifiers
100493918
GO:0005085
GO:0007165
GO:0023052
GO:0035556
GO:0046872
GO:0098772
Participates
as a member of
RHOA GEFs [cytosol] (Xenopus tropicalis)
RAC2 GEFs [cytosol] (Xenopus tropicalis)
RHOG GEFs [cytosol] (Xenopus tropicalis)
GEFs [cytosol] (Xenopus tropicalis)
VAV1,2,3 [cytosol] (Xenopus tropicalis)
as a candidate of
CDC42 GEFs [cytosol] (Xenopus tropicalis)
RAC1 GEFs [cytosol] (Xenopus tropicalis)
VAV family [cytosol] (Xenopus tropicalis)
as an input of
p-EPHs bind VAV2,3 (Xenopus tropicalis)
Recruitment of VAV and BTK to p-SLP-76 (Xenopus tropicalis)
as a component of
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Xenopus tropicalis)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Xenopus tropicalis)
Other forms of this molecule
phospho-vav3 [cytosol]
Inferred From
VAV2,VAV3 [cytosol]
(Homo sapiens)
VAV3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_012817964.1
ENSEMBL
ENSXETP00000021911
,
ENSXETT00000021911
Xenbase
XB-GENE-6075609
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