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PAK3 [cytosol]
Stable Identifier
R-XTR-428457
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
A0A6I8R511
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
EPH-Ephrin signaling (Xenopus tropicalis)
Ephrin signaling (Xenopus tropicalis)
PAK binds RAC and bPIX (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAKs autophosphorylate (Xenopus tropicalis)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Semaphorin interactions (Xenopus tropicalis)
Sema3A PAK dependent Axon repulsion (Xenopus tropicalis)
Activation of PAK by Rac1 (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1,2,3 dimer [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Autophosphorylation of PAK (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Costimulation by the CD28 family (Xenopus tropicalis)
CD28 co-stimulation (Xenopus tropicalis)
CD28 dependent Vav1 pathway (Xenopus tropicalis)
Activation of PAKs by RAC1 and CDC42 (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1,2,3 dimer [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
TCR signaling (Xenopus tropicalis)
Generation of second messenger molecules (Xenopus tropicalis)
NCK binds PAK (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
p-SLP-76:NCK:PAK [cytosol] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
C-type lectin receptors (CLRs) (Xenopus tropicalis)
CD209 (DC-SIGN) signaling (Xenopus tropicalis)
PAK phosphorylates p21 RAF1 on S338 (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK6/MAPK4 signaling (Xenopus tropicalis)
Activation of PAKs by RAC1 and CDC42 (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1,2,3 dimer [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Autophosphorylation of PAK1,2,3 (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
VEGFR2 mediated vascular permeability (Xenopus tropicalis)
PAK1-3 autophosphorylates (Xenopus tropicalis)
PAK1,2,3 dimer [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1-3 dimer disassociates (Xenopus tropicalis)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 dimer [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
RAC1 binds PAK1-3 (Xenopus tropicalis)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Xenopus tropicalis)
PAK1,2,3 dimer [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK1,2,3 dimer [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase Effectors (Xenopus tropicalis)
RHO GTPases activate PAKs (Xenopus tropicalis)
Autophosphorylation of PAK1,2,3 (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
RAC1 and CDC42 activate PAK3 (Xenopus tropicalis)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
RHO GTPase cycle (Xenopus tropicalis)
RAC1 GTPase cycle (Xenopus tropicalis)
RAC1 binds effectors at the plasma membrane (Xenopus tropicalis)
RAC1 effectors [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
RAC1:GTP:RAC1 effectors [plasma membrane] (Xenopus tropicalis)
RAC1 effectors [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
RHOU GTPase cycle (Xenopus tropicalis)
RHOU binds effectors at the plasma membrane (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
RHOU:GTP:RHOU effectors [plasma membrane] (Xenopus tropicalis)
RHOU effectors [cytosol] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
PAK3 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A6I8R511
Reference Genes
BioGPS Gene:100495025
ENSEMBL:ENSXETG00000012421
Monarch:100495025
NCBI Gene:100495025
Reference Transcript
RefSeq:XM_012969188.3
RefSeq:XM_004916850.4
Other Identifiers
100495025
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005737
GO:0016301
GO:0016310
GO:0016740
GO:0140096
Participates
as an output of
RAC1 and CDC42 activate PAK3 (Xenopus tropicalis)
as a component of
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Xenopus tropicalis)
PAK3 dimer [cytosol] (Xenopus tropicalis)
as a member of
PAK1,2,3 [cytosol] (Xenopus tropicalis)
Other forms of this molecule
phospho-p-S154,T436-PAK3 [plasma membrane]
phospho-p-S154,T436-PAK3 [cytosol]
Inferred From
PAK3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_004916907.1
,
XP_012824642.1
Xenbase
XB-GENE-961764
Ensembl
ENSXETG00000012421
,
ENSXETT00000087041
,
ENSXETP00000076291
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