Reactome | s1pr2 [plasma membrane]

s1pr2 [plasma membrane]

Stable Identifier

R-XTR-419419

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

S1PR2, A0A803J917

Locations in the PathwayBrowser

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Signal Transduction (Xenopus tropicalis)

- Signaling by GPCR (Xenopus tropicalis)
  - GPCR downstream signalling (Xenopus tropicalis)
    - G alpha (i) signalling events (Xenopus tropicalis)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5:S1P [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5 [plasma membrane] (Xenopus tropicalis)
        
        s1pr2 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5:S1P [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5 [plasma membrane] (Xenopus tropicalis)
        
        s1pr2 [plasma membrane] (Xenopus tropicalis)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5:S1P [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5 [plasma membrane] (Xenopus tropicalis)
        
        s1pr2 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5:S1P [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5 [plasma membrane] (Xenopus tropicalis)
        
        s1pr2 [plasma membrane] (Xenopus tropicalis)
      - The Ligand:GPCR:Gi complex dissociates (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5:S1P [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5 [plasma membrane] (Xenopus tropicalis)
        
        s1pr2 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5:S1P [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5 [plasma membrane] (Xenopus tropicalis)
        
        s1pr2 [plasma membrane] (Xenopus tropicalis)
  - GPCR ligand binding (Xenopus tropicalis)
    - Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
      - Lysosphingolipid and LPA receptors (Xenopus tropicalis)
        
        S1PR2-5 bind S1P (Xenopus tropicalis)
        
        S1PR2-5 [plasma membrane] (Xenopus tropicalis)
        
        s1pr2 [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5:S1P [plasma membrane] (Xenopus tropicalis)
        
        S1PR2-5 [plasma membrane] (Xenopus tropicalis)
        
        s1pr2 [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A803J917

Gene Names

s1pr2

Reference Genes

BioGPS Gene:100497836 s1pr2

ENSEMBL:ENSXETG00000041702

KEGG Gene (Xenopus tropicalis):100497836 s1pr2

Monarch:100497836 s1pr2

NCBI Gene:100497836 s1pr2

Reference Transcript

RefSeq:XM_004918817.4 s1pr2

Other Identifiers

100497836

GO:0003376

GO:0004930

GO:0005886

GO:0007186

GO:0016020

GO:0023052

GO:0038036

GO:0060089

Participates

as a member of

S1PR2-5 [plasma membrane] (Xenopus tropicalis)

Inferred From

S1PR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_004918874.1

Xenbase

XB-GENE-6037489

Ensembl

ENSXETT00000120695, ENSXETG00000041702, ENSXETP00000104370