Reactome | lpar1 [plasma membrane]

lpar1 [plasma membrane]

Stable Identifier

R-XTR-419354

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

LPAR1, A4IHT5

Locations in the PathwayBrowser

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Signal Transduction (Xenopus tropicalis)

- Signaling by GPCR (Xenopus tropicalis)
  - GPCR downstream signalling (Xenopus tropicalis)
    - G alpha (i) signalling events (Xenopus tropicalis)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
      - The Ligand:GPCR:Gi complex dissociates (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
    - G alpha (q) signalling events (Xenopus tropicalis)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
      - The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)
        
        GPCRs that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
  - GPCR ligand binding (Xenopus tropicalis)
    - Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
      - Lysosphingolipid and LPA receptors (Xenopus tropicalis)
        
        LPA-binding receptors bind LPA (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
        
        LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)
        
        lpar1 [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A4IHT5

Gene Names

lpar1

Reference Genes

BioGPS Gene:100124893 lpar1

ENSEMBL:ENSXETG00000002597

KEGG Gene (Xenopus tropicalis):100124893 lpar1

Monarch:100124893 lpar1

NCBI Gene:100124893 lpar1

Reference Transcript

Other Identifiers

100124893

GO:0004930

GO:0005768

GO:0005886

GO:0007165

GO:0007186

GO:0009986

GO:0016020

GO:0023052

GO:0031410

GO:0043226

GO:0060089

GO:0070915

Participates

as a member of

LPAR1,2,3,5 [plasma membrane] (Xenopus tropicalis)

Inferred From

LPAR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001096313.1, XP_012819199.1, XP_012819232.1

Xenbase

XB-GENE-958415

Ensembl

ENSXETG00000002597, ENSXETP00000100592, ENSXETT00000069403

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