Reactome | htr2a [plasma membrane]

htr2a [plasma membrane]

Stable Identifier

R-XTR-390947

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

HTR2A, A0A6I8PRA9

Locations in the PathwayBrowser

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Signal Transduction (Xenopus tropicalis)

- Signaling by GPCR (Xenopus tropicalis)
  - GPCR downstream signalling (Xenopus tropicalis)
    - G alpha (q) signalling events (Xenopus tropicalis)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C:5HT [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C [plasma membrane] (Xenopus tropicalis)
        
        htr2a [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C:5HT [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C [plasma membrane] (Xenopus tropicalis)
        
        htr2a [plasma membrane] (Xenopus tropicalis)
      - The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)
        
        GPCRs that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C [plasma membrane] (Xenopus tropicalis)
        
        htr2a [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C:5HT [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C [plasma membrane] (Xenopus tropicalis)
        
        htr2a [plasma membrane] (Xenopus tropicalis)
  - GPCR ligand binding (Xenopus tropicalis)
    - Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
      - Amine ligand-binding receptors (Xenopus tropicalis)
        
        Serotonin receptors (Xenopus tropicalis)
        
        5-HT2 receptor can bind serotonin (Xenopus tropicalis)
        
        HTR2A-C [plasma membrane] (Xenopus tropicalis)
        
        htr2a [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C:5HT [plasma membrane] (Xenopus tropicalis)
        
        HTR2A-C [plasma membrane] (Xenopus tropicalis)
        
        htr2a [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A6I8PRA9

Gene Names

htr2a

Reference Genes

BioGPS Gene:100492782 htr2a

ENSEMBL:ENSXETG00000032623

KEGG Gene (Xenopus tropicalis):100492782 htr2a

Monarch:100492782 htr2a

NCBI Gene:100492782 htr2a

Reference Transcript

RefSeq:XM_018091674.2 htr2a

Other Identifiers

100492782

GO:0004930

GO:0004993

GO:0005886

GO:0005901

GO:0007165

GO:0007186

GO:0016020

GO:0023052

GO:0030424

GO:0030425

GO:0031410

GO:0031982

GO:0042995

GO:0043226

GO:0045202

GO:0060089

GO:0098664

GO:0098793

Participates

as a member of

HTR2A-C [plasma membrane] (Xenopus tropicalis)

Inferred From

HTR2A [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_017947163.1

Ensembl

ENSXETP00000060342, ENSXETT00000062464, ENSXETG00000032623

Xenbase

XB-GENE-986221

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