Reactome | cenpm [cytosol]

cenpm [cytosol]

Stable Identifier

R-XTR-375290

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

CENPM, A4IHL0

Locations in the PathwayBrowser

Expand all

Cell Cycle (Xenopus tropicalis)

- Cell Cycle Checkpoints (Xenopus tropicalis)
  - Mitotic Spindle Checkpoint (Xenopus tropicalis)
    - Amplification of signal from the kinetochores (Xenopus tropicalis)
      - Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Xenopus tropicalis)
        
        MAD2 associates with the Mad1 kinetochore complex (Xenopus tropicalis)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Xenopus tropicalis)
        
        Mad1:kinetochore complex [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Mad1:kinetochore complex [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        MAD2 converted to an inhibitory state via interaction with Mad1 (Xenopus tropicalis)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Xenopus tropicalis)
        
        Mad1:kinetochore complex [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Release of activated MAD2 from kinetochores (Xenopus tropicalis)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Xenopus tropicalis)
        
        Mad1:kinetochore complex [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Mad1:kinetochore complex [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
- Cell Cycle, Mitotic (Xenopus tropicalis)
  - M Phase (Xenopus tropicalis)
    - Mitotic Metaphase and Anaphase (Xenopus tropicalis)
      - Mitotic Anaphase (Xenopus tropicalis)
        
        Separation of Sister Chromatids (Xenopus tropicalis)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Xenopus tropicalis)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Separation of sister chromatids (Xenopus tropicalis)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Sister Centromere:Kinetochore:Microtubules [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
    - Mitotic Prometaphase (Xenopus tropicalis)
      - EML4 and NUDC in mitotic spindle formation (Xenopus tropicalis)
        
        EML4 recruits NUDC to mitotic spindle (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
      - Resolution of Sister Chromatid Cohesion (Xenopus tropicalis)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Xenopus tropicalis)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Kinetochore assembly (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Xenopus tropicalis)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Xenopus tropicalis)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Xenopus tropicalis)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Xenopus tropicalis)
        
        Microtubule-bound kinetochore [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by Rho GTPases (Xenopus tropicalis)
  - RHO GTPase Effectors (Xenopus tropicalis)
    - RHO GTPases Activate Formins (Xenopus tropicalis)
      - AURKB phosphorylates DIAPH2-2 at kinetochores (Xenopus tropicalis)
        
        Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)
        
        Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Xenopus tropicalis)
        
        Kinetochore [cytosol] (Xenopus tropicalis)
        
        CCAN network [cytosol] (Xenopus tropicalis)
        
        cenpm [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A4IHL0

Gene Names

cenpm

Reference Genes

BioGPS Gene:549929 cenpm

ENSEMBL:ENSXETG00000003692 cenpm

ENSEMBL:ENSXETG00000027331

KEGG Gene (Xenopus tropicalis):549929 cenpm

Monarch:549929 cenpm

NCBI Gene:549929 cenpm

Reference Transcript

RefSeq:NM_001017175.2 cenpm

Other Identifiers

100485889

GO:0000139

GO:0003674

GO:0003824

GO:0004571

GO:0005509

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0005737

GO:0005783

GO:0005794

GO:0006491

GO:0008150

GO:0016020

GO:0016798

GO:0043167

GO:0043226

Str.21661.1.A1_s_at

StrEns.4908.1.S1_at

Participant Of

hasComponent

CCAN network [cytosol]

Inferred From

CENPM [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001017175.1

Ensembl

ENSXETG00000003692, ENSXETT00000007975, ENSXETP00000007975

Cite Us!