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JAK2 [cytosol]
Stable Identifier
R-XTR-210620
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
A0JM01
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Growth hormone receptor signaling (Xenopus tropicalis)
JAK2 phosphorylation (Xenopus tropicalis)
PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Xenopus tropicalis)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Interferon Signaling (Xenopus tropicalis)
Interferon gamma signaling (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Xenopus tropicalis)
IFNGR2:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Xenopus tropicalis)
IFNGR2:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Prolactin receptor signaling (Xenopus tropicalis)
JAK2 phosphorylation (Xenopus tropicalis)
PRLR ligands:Activated PRLR:JAK2 dimer:SH2B1 beta [plasma membrane] (Xenopus tropicalis)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR activation (Xenopus tropicalis)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR binds SCF beta-TrCP complex (Xenopus tropicalis)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Xenopus tropicalis)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR is phosphorylated at Ser-349 (Xenopus tropicalis)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR:JAK2 dimerizes (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Prolactin receptor is internalized (Xenopus tropicalis)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Xenopus tropicalis)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Prolactin receptor ligands bind the prolactin receptor (Xenopus tropicalis)
PRLR ligands:PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Xenopus tropicalis)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
PRLR:JAK2 dimer [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-12 family signaling (Xenopus tropicalis)
Interleukin-27 signaling (Xenopus tropicalis)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Xenopus tropicalis)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Interleukin-35 Signalling (Xenopus tropicalis)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Xenopus tropicalis)
IL12RB2:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Xenopus tropicalis)
IL12RB2:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Xenopus tropicalis)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Xenopus tropicalis)
IL35:(IL12RB2:JAK2 dimer) [plasma membrane] (Xenopus tropicalis)
IL12RB2:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Interleukin-4 and Interleukin-13 signaling (Xenopus tropicalis)
IL4R binds JAK2 (Xenopus tropicalis)
IL4R:JAK2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Interleukin-6 family signaling (Xenopus tropicalis)
IL-6-type cytokine receptor ligand interactions (Xenopus tropicalis)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Xenopus tropicalis)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAKs bind LIFR (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAKs:LIFR [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAKs bind OSMR (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAKs:OSMR [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Interleukin-6 signaling (Xenopus tropicalis)
Assembly of hexameric IL-6 receptor (Xenopus tropicalis)
IL6 receptor hexamer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6 receptor trimer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
IL6 receptor trimer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAK activation (Xenopus tropicalis)
IL6 receptor hexamer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6 receptor trimer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Signaling by Erythropoietin (Xenopus tropicalis)
EPOR binds EPOR agonists (Xenopus tropicalis)
EPOR agonists:EPOR:JAK2:LYN:IRS2 [plasma membrane] (Xenopus tropicalis)
EPOR:JAK2:LYN:IRS2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
EPOR:JAK2:LYN:IRS2 [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by SCF-KIT (Xenopus tropicalis)
JAK2 binds to p-KIT (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAK2:SFKS:p-KIT complex [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
Phosphorylation of JAK2 (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
JAK2:SFKS:p-KIT complex [plasma membrane] (Xenopus tropicalis)
JAK2 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0JM01
Reference Genes
BioGPS Gene:100036599
ENSEMBL:ENSXETG00000000586
KEGG Gene (Xenopus tropicalis):100036599
Monarch:100036599
NCBI Gene:100036599
Reference Transcript
RefSeq:NM_001097165.1
Other Identifiers
100036599
GO:0000166
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005524
GO:0005634
GO:0005856
GO:0006325
GO:0007165
GO:0008284
GO:0012505
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0035556
GO:0036211
GO:0042393
GO:0043226
GO:0140096
Participates
as a component of
IL12RB2:JAK2 [plasma membrane] (Xenopus tropicalis)
p(S349)-PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
PRLR:JAK2 [plasma membrane] (Xenopus tropicalis)
EPOR:JAK2:LYN:IRS2 [plasma membrane] (Xenopus tropicalis)
JAK2:SFKS:p-KIT complex [plasma membrane] (Xenopus tropicalis)
IL4R:JAK2 [plasma membrane] (Xenopus tropicalis)
IFNGR2:JAK2 [plasma membrane] (Xenopus tropicalis)
as a candidate of
JAK2, JAK3 [cytosol] (Xenopus tropicalis)
as a member of
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
as an input of
JAK2 binds to p-KIT (Xenopus tropicalis)
IL4R binds JAK2 (Xenopus tropicalis)
Other forms of this molecule
phospho-p-JAK2 [cytosol]
phospho-p-Y813-JAK2 [cytosol]
JAK2 [endosome lumen]
phospho-p-12Y-JAK2 [cytosol]
phospho-p-Y1007-JAK2 [cytosol]
Inferred From
JAK2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001090634.1
Xenbase
XB-GENE-483712
Ensembl
ENSXETG00000000586
,
ENSXETT00000001294
,
ENSXETP00000001294
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