Reactome | p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]

p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]

Stable Identifier

R-XTR-205310

Type

Complex

Species

Xenopus tropicalis

Compartment

plasma membrane

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 2 phospho-p-7Y-KIT [plasma membrane] (Xenopus tropicalis)
sSCF dimer [extracellular region] (Xenopus tropicalis)

Participates

as an input of

Interaction of other adapter proteins with p-KIT (Xenopus tropicalis)
Interaction of other tyrosine kinases with p-KIT (Xenopus tropicalis)
LNK binds to p-KIT and inhibit downstream signaling (Xenopus tropicalis)
GRB2:SOS interacts with p-KIT (Xenopus tropicalis)
Direct recruitment of PI3K to p-KIT (Xenopus tropicalis)

as a component of

Adapter proteins:p-KIT complex [plasma membrane] (Xenopus tropicalis)
Tyrosine kinases:p-KIT complex [plasma membrane] (Xenopus tropicalis)
LNK:p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] (Xenopus tropicalis)
SFKs:p-KIT complex [plasma membrane] (Xenopus tropicalis)
GRB2:SOS1:p-KIT complex [plasma membrane] (Xenopus tropicalis)
PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Xenopus tropicalis)

as an output of

Autophosphorylation of KIT (Xenopus tropicalis)

This entity regulates

Positively

RPS6KA1-dependent phosphorylation of MITF-M (Xenopus tropicalis)
MAPK1-dependent phosphorylation of MITF-M (Xenopus tropicalis)

Inferred From

p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] (Homo sapiens)