Reactome | cttn [cytosol]

cttn [cytosol]

Stable Identifier

R-XTR-201894

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

CTTN, F6UFG9

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Xenopus tropicalis)

- Membrane Trafficking (Xenopus tropicalis)
  - Clathrin-mediated endocytosis (Xenopus tropicalis)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - BAR domain proteins recruit dynamin (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Xenopus tropicalis)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - Endophilins recruit synaptojanins to the clathrin-coated pit (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Xenopus tropicalis)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Xenopus tropicalis)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Xenopus tropicalis)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - RAB5 and GAPVD1 bind AP-2 (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - SNX9 recruits components of the actin polymerizing machinery (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
    - SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Xenopus tropicalis)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Xenopus tropicalis)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Xenopus tropicalis)
        
        WASL,CTTN [cytosol] (Xenopus tropicalis)
        
        cttn [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6UFG9

Gene Names

cttn

Reference Genes

BioGPS Gene:100490678 cttn

ENSEMBL:ENSXETG00000003797

KEGG Gene (Xenopus tropicalis):100490678 cttn

Monarch:100490678 cttn

NCBI Gene:100490678 cttn

Reference Transcript

RefSeq:XM_002941229.2 cttn

Other Identifiers

100038122

GO:0000139

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005794

GO:0005856

GO:0005884

GO:0005886

GO:0007010

GO:0008076

GO:0008092

GO:0008150

GO:0016757

GO:0022607

GO:0030027

GO:0030041

GO:0030427

GO:0030833

GO:0030864

GO:0032991

GO:0043226

GO:0051015

GO:0065003

StrEns.2513.1.S1_a_at

Participant Of

hasMember

WASL,CTTN [cytosol]

Inferred From

CTTN [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_002941275.1

Ensembl

ENSXETT00000008263, ENSXETP00000008263, ENSXETG00000003797

Cite Us!