Reactome | elmo1 [cytosol]

elmo1 [cytosol]

Stable Identifier

R-XTR-200932

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

ELMO1, A0A6I8RDI5

Locations in the PathwayBrowser

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Signal Transduction (Xenopus tropicalis)

- Signaling by Non-Receptor Tyrosine Kinases (Xenopus tropicalis)
  - Signaling by PTK6 (Xenopus tropicalis)
    - PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Xenopus tropicalis)
      - Activation of RAC1 by the PXN:CRK complex (Xenopus tropicalis)
        
        p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        elmo1 [cytosol] (Xenopus tropicalis)
- Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
  - Signaling by VEGF (Xenopus tropicalis)
    - VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
      - DOCK180:ELMO binds CRK (Xenopus tropicalis)
        
        CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Xenopus tropicalis)
        
        CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        elmo1 [cytosol] (Xenopus tropicalis)
        
        DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        elmo1 [cytosol] (Xenopus tropicalis)
      - DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Xenopus tropicalis)
        
        CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        elmo1 [cytosol] (Xenopus tropicalis)
        
        CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Xenopus tropicalis)
        
        CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)
        
        elmo1 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A6I8RDI5

Gene Names

elmo1

Reference Genes

ENSEMBL:ENSXETG00000031168

Reference Transcript

RefSeq:XM_031903800.1 elmo1

Other Identifiers

100380096

GO:0005737

GO:0006909

GO:0006915

GO:0012501

GO:0016192

GO:0017124

Participates

as a member of

ELMO1,ELMO2 [cytosol] (Xenopus tropicalis)

Inferred From

ELMO1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_031759660.1

Xenbase

XB-GENE-1013559

Ensembl

ENSXETP00000079131, ENSXETT00000084103, ENSXETG00000031168

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