Reactome | cd3g [plasma membrane]

cd3g [plasma membrane]

Stable Identifier

R-XTR-198171

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

CD3D, F6VBE7

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Adaptive Immune System (Xenopus tropicalis)
  - TCR signaling (Xenopus tropicalis)
    - Phosphorylation of CD3 and TCR zeta chains (Xenopus tropicalis)
      - Activation of Lck (Xenopus tropicalis)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Xenopus tropicalis)
        
        T-cell receptor complex [plasma membrane] (Xenopus tropicalis)
        
        CD3 epsilon delta [plasma membrane] (Xenopus tropicalis)
        
        cd3g [plasma membrane] (Xenopus tropicalis)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Xenopus tropicalis)
        
        T-cell receptor complex [plasma membrane] (Xenopus tropicalis)
        
        CD3 epsilon delta [plasma membrane] (Xenopus tropicalis)
        
        cd3g [plasma membrane] (Xenopus tropicalis)
      - Inactivation of Lck by Csk (Xenopus tropicalis)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Xenopus tropicalis)
        
        T-cell receptor complex [plasma membrane] (Xenopus tropicalis)
        
        CD3 epsilon delta [plasma membrane] (Xenopus tropicalis)
        
        cd3g [plasma membrane] (Xenopus tropicalis)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Xenopus tropicalis)
        
        T-cell receptor complex [plasma membrane] (Xenopus tropicalis)
        
        CD3 epsilon delta [plasma membrane] (Xenopus tropicalis)
        
        cd3g [plasma membrane] (Xenopus tropicalis)
      - Phosphorylation of ITAM motifs in CD3 complexes (Xenopus tropicalis)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Xenopus tropicalis)
        
        T-cell receptor complex [plasma membrane] (Xenopus tropicalis)
        
        CD3 epsilon delta [plasma membrane] (Xenopus tropicalis)
        
        cd3g [plasma membrane] (Xenopus tropicalis)
    - Translocation of ZAP-70 to Immunological synapse (Xenopus tropicalis)
      - Phosphorylation of ZAP-70 by Lck (Xenopus tropicalis)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Xenopus tropicalis)
        
        T-cell receptor complex [plasma membrane] (Xenopus tropicalis)
        
        CD3 epsilon delta [plasma membrane] (Xenopus tropicalis)
        
        cd3g [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6VBE7

Gene Names

cd3g

Reference Genes

BioGPS Gene:100216101 cd3g

ENSEMBL:ENSXETG00000010117

KEGG:xtr:100216101 cd3g

Monarch:100216101 cd3g

NCBI Gene:100216101 cd3g

UCSC:F6VBE7 cd3g

Reference Transcript

RefSeq:NM_001142083.1 cd3g

Other Identifiers

100216101

GO:0002376

GO:0004888

GO:0007166

GO:0009897

GO:0016020

GO:0042105

GO:0045059

Participates

as a member of

AP-2 dileucine-containing cargo [plasma membrane] (Xenopus tropicalis)

as a component of

CD3 epsilon delta [plasma membrane] (Xenopus tropicalis)

Other forms of this molecule

cd3g [plasma membrane]

phospho-cd3g [plasma membrane]

Inferred From

CD3D [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001135555.1

ENSEMBL

ENSXETT00000022306, ENSXETP00000022306, ENSXETG00000010117

Xenbase

XB-GENE-480422

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