Reactome | FCER1A [plasma membrane]

FCER1A [plasma membrane]

Stable Identifier

R-XTR-197802

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

F6PVZ1

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Innate Immune System (Xenopus tropicalis)
  - Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
    - Allergen dependent IgE bound FCERI aggregation (Xenopus tropicalis)
      - FCERI:IgE [plasma membrane] (Xenopus tropicalis)
        
        FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
      - FCERI:IgE:allergin aggregate [plasma membrane] (Xenopus tropicalis)
        
        FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        FCERI:IgE [plasma membrane] (Xenopus tropicalis)
        
        FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
    - FCERI mediated Ca+2 mobilization (Xenopus tropicalis)
      - Phosphorylation of TEC kinases by p-SYK (Xenopus tropicalis)
        
        Clustered p:LYN:p-FCERI:IgE:allergin:p-6Y-SYK [plasma membrane] (Xenopus tropicalis)
        
        Allergin:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
    - FCERI mediated MAPK activation (Xenopus tropicalis)
      - Phosphorylation of SHC by SYK kinase (Xenopus tropicalis)
        
        Clustered p:LYN:p-FCERI:IgE:allergin:p-6Y-SYK [plasma membrane] (Xenopus tropicalis)
        
        Allergin:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
      - Phosphorylation of SLP-76 by p-SYK (Xenopus tropicalis)
        
        Clustered p:LYN:p-FCERI:IgE:allergin:p-6Y-SYK [plasma membrane] (Xenopus tropicalis)
        
        Allergin:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
    - FCERI mediated NF-kB activation (Xenopus tropicalis)
      - Phosphorylation of PKC-theta (Xenopus tropicalis)
        
        Allergin:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
    - Phosphorylation of beta and gamma subunits by LYN (Xenopus tropicalis)
      - Allergin:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
      - FCERI:IgE:allergin aggregate [plasma membrane] (Xenopus tropicalis)
        
        FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        FCERI:IgE [plasma membrane] (Xenopus tropicalis)
        
        FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
    - Recruitment of SYK to p-FCERI gamma subunit (Xenopus tropicalis)
      - Allergin:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)
      - Clustered p:LYN:p-FCERI:IgE:allergin:SYK [plasma membrane] (Xenopus tropicalis)
        
        Allergin:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI aggregate [plasma membrane] (Xenopus tropicalis)
        
        p-FCERI [plasma membrane] (Xenopus tropicalis)
        
        Homologues of FCER1A [plasma membrane] (Xenopus tropicalis)
        
        FCER1A [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6PVZ1

Reference Genes

ENSEMBL:ENSXETG00000013088

Other Identifiers

100490964

ENSXETG00000008235

ENSXETP00000028670

ENSXETT00000018225

EntrezGene:100490964

EntrezGene:LOC100490964

GO:0006259

GO:0006281

GO:0006950

GO:0008150

GO:0022607

GO:0034641

GO:0051276

GO:0051382

GO:0065003

IPR018552

LOC100490964

PF09415

XM_002942767

XM_004918563

XP_002942813

XP_004918620

Participant Of

hasMember

Homologues of FCER1A [plasma membrane]

Other forms of this molecule

cleaved GPI-FCGR3B [extracellular region]

GPI-FCGR3B [plasma membrane]

FCGR2B [plasma membrane]

FCGR1B [plasma membrane]

FCGR1A [clathrin-coated endocytic vesicle membrane]

FCGR1B [clathrin-coated endocytic vesicle membrane]

FCGR1A [early endosome membrane]

FCGR1B [early endosome membrane]

FCGR3B [plasma membrane]

FCGR3B [secretory granule membrane]

FCGR2A [secretory granule membrane]

FCGR2A [plasma membrane]

phospho-p-Y288,Y304-FCGR2A [plasma membrane]

FCGR1A [plasma membrane]

FCGR3A [plasma membrane]

Inferred From

FCER1A [plasma membrane] (Homo sapiens)