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AKR1C4 [cytosol]
Stable Identifier
R-XTR-192142-3
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
Q0VGY1
Locations in the PathwayBrowser
Expand all
Drug ADME (Xenopus tropicalis)
Prednisone ADME (Xenopus tropicalis)
AKR1C1 hydrogenates PREDN,PREDL (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Arachidonic acid metabolism (Xenopus tropicalis)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Xenopus tropicalis)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
PGH2 is reduced to PGF2a by AKR1C3 (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
Metabolism of steroids (Xenopus tropicalis)
Bile acid and bile salt metabolism (Xenopus tropicalis)
Synthesis of bile acids and bile salts (Xenopus tropicalis)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Xenopus tropicalis)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Xenopus tropicalis)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Xenopus tropicalis)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of fat-soluble vitamins (Xenopus tropicalis)
Retinoid metabolism and transport (Xenopus tropicalis)
AKRs reduce RBP2:atRAL to RBP2:atROL (Xenopus tropicalis)
AKRs [cytosol] (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
Sensory Perception (Xenopus tropicalis)
Visual phototransduction (Xenopus tropicalis)
Retinoid metabolism and transport (Xenopus tropicalis)
AKRs reduce RBP2:atRAL to RBP2:atROL (Xenopus tropicalis)
AKRs [cytosol] (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
Signaling by Retinoic Acid (Xenopus tropicalis)
RA biosynthesis pathway (Xenopus tropicalis)
AKR1C3 reduces atRAL to atROL (Xenopus tropicalis)
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
AKR1C4 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q0VGY1
Reference Genes
BioGPS Gene:779627
ENSEMBL:ENSXETG00000049306
KEGG Gene (Xenopus tropicalis):779627
Monarch:779627
NCBI Gene:779627
Reference Transcript
RefSeq:NM_001078713.1
Other Identifiers
100490956
734139
779627
779650
GO:0003824
GO:0016491
Participates
as a member of
Homologues of AKR1C4 [cytosol] (Xenopus tropicalis)
Inferred From
AKR1C4 [cytosol]
(Homo sapiens)
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001072181.1
Ensembl
ENSXETT00000084191
,
ENSXETG00000049306
,
ENSXETP00000087783
Xenbase
XB-GENE-5821909
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