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phospho-p-S176,S180-CHUK [cytosol]
Stable Identifier
R-XTR-177667
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
Q28DZ1
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
TNFR2 non-canonical NF-kB pathway (Xenopus tropicalis)
NIK-->noncanonical NF-kB signaling (Xenopus tropicalis)
Active NIK phosphorylates IKKA dimer (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Xenopus tropicalis)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
C-type lectin receptors (CLRs) (Xenopus tropicalis)
CLEC7A (Dectin-1) signaling (Xenopus tropicalis)
Dectin-1 mediated noncanonical NF-kB signaling (Xenopus tropicalis)
Active NIK phosphorylates IKKA dimer (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer:p100:RELB [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Xenopus tropicalis)
Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [cytosol] (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer [cytosol] (Xenopus tropicalis)
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
phospho-p-S176,S180-CHUK [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q28DZ1
Reference Genes
BioGPS Gene:101732839
BioGPS Gene:549654
ENSEMBL:ENSXETG00000017643
KEGG Gene (Xenopus tropicalis):549654
Monarch:101732839
Monarch:549654
NCBI Gene:101732839
NCBI Gene:549654
Reference Transcript
RefSeq:NM_001310117.1
RefSeq:NM_001016900.2
Other Identifiers
101732839
549654
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005634
GO:0005737
GO:0008384
GO:0016740
GO:0023052
GO:0036211
GO:0043226
GO:0050896
GO:0140096
Participates
as a component of
p-S176,S180-IKKA dimer [cytosol] (Xenopus tropicalis)
Other forms of this molecule
phospho-p-T23-CHUK [cytosol]
CHUK [cytosol]
Inferred From
p-S176,S180-CHUK [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 176 (in Homo sapiens)
Coordinate
176
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 180 (in Homo sapiens)
Coordinate
180
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001016900.1
,
NP_001297046.1
IntEnz
2.7.11.10
Xenbase
XB-GENE-5910008
Ensembl
ENSXETT00000038296
,
ENSXETP00000038296
,
ENSXETG00000017643
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